Development and Evaluation of a Manganese and Iron Food Frequency Questionnaire for Pediatrics.

Manganese (Mn) is an essential nutrient, but overexposure can lead to neurotoxicity. Given the essentiality of Mn in the diet, particularly during children's growth and development, it is imperative to quantify dietary Mn intake in populations that may be exposed to industrial sources of Mn. Dietary absorption of Mn is inversely associated with iron (Fe) stores, yet there is currently no food frequency questionnaire (FFQ) to assess dietary Mn and Fe intake. The study objective was to develop and evaluate the validity of a FFQ to measure dietary Mn and Fe intake in pediatrics by comparing the estimated intakes of Mn and Fe with biomarkers: Mn in blood and hair and Fe in serum. This study utilized a subset of the Communities Actively Researching Exposure Study (CARES) population residing in Guernsey County, Ohio. Dietary Mn was not correlated with either blood or hair Mn; however, dietary Mn and serum ferritin were significantly correlated, with a correlation coefficient of 0.51, p < 0.01. Moreover, dietary Fe and serum ferritin were also significantly correlated, with a correlation coefficient of 0.51, p < 0.01. This FFQ is a valid measurement tool for Fe intake as measured by serum ferritin; however, Mn intake did not correlate with either blood or hair Mn.

Social capital, social support, and food insecurity in food pantry users.

The purpose of this study was to examine the relationship between food security, social capital, and social support among urban food pantry users in Cincinnati. In-person interviews with 53 participants were completed using the U.S. Household Food Security Survey Module, Social Capital questionnaire, and Social Support questionnaire. Social capital was assessed through four subscales using a Likert scale, with a response range 1 to 4, and social support was measured by rating significant others' emotional, informational, and instrumental support as well as companionship (ranged from 0 to 4). The findings suggested that there were no significant associations among them. This may be due to a small sample size. Thus, the associations need to be examined with a larger sample. Further, a qualitative approach may be necessary to explore the contextual nature of social capital and social support related to food security.

Sociocultural influences on the determinants of breast-feeding by Latina mothers in the Cincinnati area.

While breast-feeding initiation and duration among US Latina women appear to decrease with acculturation, health care providers in the Greater Cincinnati area have noted lower rates of breast-feeding among even first-generation Latina immigrants. This study's purpose was to identify determinants of breast-feeding for Latina mothers in Cincinnati through qualitative interviews and Spanish Breastfeeding Self-Efficacy Scale ratings. Our findings suggest that, along with similar levels of breast-feeding self-confidence, foreign-born Latina women in the Greater Cincinnati area share similar breast-feeding determinants with the general population. However, characteristics of these determinants and their impact vary because of unique pressures experienced by this community.

Assessing dietary variety in children: development and validation of a predictive equation.

BACKGROUND: Research indicates that the length of time needed to describe dietary diversity is approximately 2 weeks. This is the first study conducted to develop a dietary variety measurement tool that is sensitive to the effect of time on dietary variety without the burden of gathering data for 2 weeks. OBJECTIVE: To determine whether 3 days of 24-hour dietary recall logs collected during a 15-day period would predict food variety as well as 15 consecutive days. The study also determined which set of 3 days (consecutive vs interval days) within a 15-day period would better predict 15-day food variety. DESIGN: Prospective survey of the dietary practices of children. SUBJECTS/SETTING: Seventy-two children aged 9 to 12 years attending fourth and fifth grades in a public elementary school in a Midwestern town in the fall of 2005. MAIN OUTCOME MEASURES: Predicted 15-day cumulative dietary variety score from 3 consecutive days and 3 interval days of dietary data. STATISTICAL ANALYSIS PERFORMED: Two prediction models were obtained from multiple linear regression analyses in which natural log-transformed (log(e)) 15-day variety scores were regressed on log(e) 3-day variety scores (consecutive and interval days). The ability of each model to predict the 15-day cumulative variety score was assessed by comparisons of mean bias, mean-squared error, coefficient of determination (R(2)), and Pearson product-moment correlation coefficients. RESULTS: Three days of dietary data accurately estimated dietary variety over time for this sample of 9- to 12-year-old children using the predictive equation generated in this study. Three interval days predicted 15-day food variety more precisely than 3 consecutive days. CONCLUSIONS: The predictive equation is accurate in estimating food variety over time for this population and, if validated in independent samples, could be applied to similar populations.

Short-term exposure to a high-protein diet differentially affects glomerular filtration rate but not Acid-base balance in older compared to younger adults.

There is conflicting evidence regarding the effects of high protein intake on kidney health, especially as it relates to age. We investigated the short-term effects of a high-protein diet on kidney function and systemic acid-base homeostasis in older compared to younger adults. The subjects were healthy men and women either between the ages of 25 and 40 years (n=12) or 55 and 70 years (n=10). They underwent a two-period crossover trial with each period consisting of 2 weeks of usual diet followed by a 1-week experimental diet. During the experimental diet period subjects consumed metabolic meals that provided either low protein content (0.5 g protein/kg/day) or high protein content (2.0 g protein/kg/day). Outcome measures included blood and urine markers of renal function and acid-base balance. An analysis of variance was used to assess differences between age groups with respect to experimental diet. The older group, mainly women, showed an increase in glomerular filtration rate after the high-protein compared to low-protein diet; the younger group did not. Urinary pH was significantly lower, and ammonium excretion was significantly higher after the high-protein diet in both age groups, but neither group developed a clinically detectable acidosis after the week of receiving a high-protein diet.

A clinical-based intervention improves diet in patients with head and neck cancer at risk for second primary cancer.

A diet rich in fruits and vegetables is associated with a reduced risk of head and neck cancer. This study was designed to assess the efficacy of an intervention to increase fruit and vegetable consumption and improve overall diet quality in patients with early stage head and neck cancer at risk for second primary cancer. The study was a crossover-controlled design with each patient being his or her own control. Patients received usual care during the control period followed by a clinical-based intervention grounded in the Social Learning Theory for 3 months. Measurements were taken at baseline, 6 months, and 12 months. The intervention consisted of a face-to-face counseling session, a phone call, and three mailings. Findings from this study indicate that these patients increased their intake of fruits (number of servings and variety), vegetables (number of servings), and improved overall diet quality while exposed to the intervention as compared with usual care.

Dietary variety increases as a function of time and influences diet quality in children.

OBJECTIVE: To investigate the changes in dietary variety over time in children and to determine the relationship between dietary variety and diet quality. DESIGN: Dietary data were collected from fourth and fifth grade students for 14 consecutive days by a registered dietitian. SETTING: Colerain School District of Cincinnati, Ohio. PARTICIPANTS: There were 33 children involved in the study. MAIN OUTCOME MEASURES: Two cumulative dietary variety scores were estimated. The first was based on the Food Guide Pyramid groups: grain, fruit, vegetable, dairy, and meat (GFVDM). The second was based on the groups highlighted by the 2000 Dietary Guidelines for variety: grain, fruit, and vegetable (GFV). Diets were analyzed for energy and nutrient content. ANALYSIS: Analysis of variance and Pearson correlation coefficients. RESULTS: Dietary variety increased over time up to 14 days. A significant difference (P <.0001) was found for the cumulative GFVDM and GFV variety scores on days 3, 7, and 14. Positive correlations were found between the GFVDM and GFV variety scores and vitamin C and fiber. CONCLUSIONS AND IMPLICATIONS: This study suggests that a 2-week period is necessary to capture food variety in children. Some associations were found between dietary variety and diet quality. New tools are needed to measure dietary variety in children.

Role of antioxidant nutrients and lipid peroxidation in premature infants with respiratory distress syndrome and bronchopulmonary dysplasia.

The objective of this study was to determine if newborn premature infants with severe respiratory distress syndrome (RDS) who developed bronchopulmonary dysplasia (BPD) demonstrate, within the first 3 days of life, lower blood levels of antioxidants and higher urine levels of lipid peroxidation products than premature infants who recovered from RDS. Perinatal variables (gestational age, birth weight, and Apgar scores) and antioxidant indices in cord and in third day of life plasma and red blood cell (RBC) samples from healthy premature infants (n = 35), infants with RDS (n = 23) and infants with BPD (n = 23) were examined. Antioxidant indices included selenium, alpha-tocopherol, total and oxidized glutathione, glutathione peroxidase, superoxide dismutase, and urinary malondialdehyde. By inferential statistics, only the perinatal variables and cord plasma selenium distinguished healthy premature infants from premature infants with RDS or BPD. From perinatal variables and antioxidant indices we calculated: (1) cord to third-day-of-life variable differences, (2) variable-to-variable ratios, and (3) ratios of a difference for one variable to a difference for any second variable. Subset regression analysis yielded an equation (adjusted R2 = 0.8839) that correctly predicted infants who developed BPD 100% of the time. Predictor variables for BPD were gestational age, Apgar at 1 min, cord and third-day-of-life RBC selenium, cord total glutathione, cord and third-day-of-life glutathione peroxidase and nine different ratios involving Apgar scores, RBC selenium, total and oxidized glutathione, alpha-tocopherol, glutathione peroxidase, and superoxide dismutase. In this study, there was no relationship between lipid peroxidation and BPD. There was a higher rate of patent ductus arteriosus, congestive heart failure, and retinopathy of prematurity in infants with BPD. This study confirms that low plasma selenium and alpha-tocopherol levels in premature infants (< or = 30 weeks' gestational age or lower) were significantly associated with an increased respiratory morbidity.