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1.
Behav Ther ; 55(4): 698-711, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38937044

ABSTRACT

Because social anxiety and depression commonly co-occur, it can be challenging to disentangle the emotional and motivational features of these conditions in everyday life contexts. In this daily diary study, we sought to understand the interplay between daily social anxiety and depression symptoms and emotion and motivation, determining whether daily symptoms are independently linked with positive affect, negative affect, and social motivation (desire to approach or to withdraw from others). Community-dwelling adults (N = 269) with a wide range of social anxiety and depression symptoms completed daily assessments for 14 consecutive days (a total of 2,986 daily surveys). Within-person analyses found that increases in social anxiety and depression symptoms were uniquely associated with elevated negative affect; only increases in depression symptoms were associated with diminished positive affect. Increases in social anxiety symptoms were associated with an elevated desire to approach others but not a desire to withdraw from others. By contrast, increases in depression symptoms were associated with a diminished desire to approach others and an elevated desire to withdraw from others. Desire for social connection may distinguish social anxiety from depression. Examining patterns of daily social motivation may enhance clinicians' ability to differentiate the difficulties that arise from social anxiety from those that arise from depression.


Subject(s)
Anxiety , Depression , Motivation , Humans , Female , Male , Adult , Depression/psychology , Depression/diagnosis , Middle Aged , Anxiety/psychology , Anxiety/diagnosis , Social Behavior , Young Adult , Aged , Affect , Diaries as Topic , Emotions , Adolescent
2.
Clin Psychol Sci ; 12(2): 237-252, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38645420

ABSTRACT

Research using psychophysiological methods holds great promise for refining clinical assessment, identifying risk factors, and informing treatment. Unfortunately, unique methodological features of existing approaches limit inclusive research participation and, consequently, generalizability. This brief overview and commentary provides a snapshot of the current state of representation in clinical psychophysiology, with a focus on the forms and consequences of ongoing exclusion of Black participants. We illustrate issues of inequity and exclusion that are unique to clinical psychophysiology, considering intersections among social constructions of Blackness and biased design of current technology used to measure electroencephalography, skin conductance, and other signals. We then highlight work by groups dedicated to quantifying and addressing these limitations. We discuss the need for reflection and input from a wider variety of stakeholders to develop and refine new technologies, given the risk of further widening disparities. Finally, we provide broad recommendations for clinical psychophysiology research.

3.
J Consult Clin Psychol ; 91(12): 731-743, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38032622

ABSTRACT

OBJECTIVE: Improvement in emotion regulation is a proposed transdiagnostic mechanism of change. However, treatment research is limited by disorder-specific investigations that assess a narrow number of emotion regulation strategies. Moreover, most assess pre-to-post-treatment change without examining short-term changes throughout psychotherapy that might influence treatment response. METHOD: To address these gaps, this study uses daily diary methodology to examine trajectories of change in use of six emotion regulation strategies during partial hospitalization psychiatric treatment. Treatment was rooted in cognitive behavioral principles and included skills adapted from empirically supported cognitive behavioral therapy (CBT) and dialectical behavior therapy (DBT) manuals. Participants were adults (N = 364; Mage = 34.6 years; 60% female; 85% non-Hispanic White) with various profiles of mood, anxiety, and obsessive-compulsive disorders who completed symptom measures at baseline and discharge and daily measures of emotion regulation. RESULTS: In the first 7 treatment days, patients increased use of engagement strategies (reappraisal, acceptance) and decreased use of disengagement (expressive suppression) and cognitive perseveration (experiential avoidance, rumination) strategies. Day-to-day trajectories found that decreased use of experiential avoidance predicted next-day changes in distraction and suppression use. In predicting treatment outcomes, steeper rates of decreased suppression use predicted reductions in anxiety, depression, and general psychopathology symptoms; similar patterns were observed for decreased rumination and experiential avoidance use and increased reappraisal use. CONCLUSION: Results add to a growing literature on the value of intentional, constructive engagement with emotional experiences as a mechanism of psychological health. (PsycInfo Database Record (c) 2023 APA, all rights reserved).


Subject(s)
Cognitive Behavioral Therapy , Emotional Regulation , Humans , Adult , Female , Male , Day Care, Medical , Psychotherapy , Emotions
4.
Am Psychol ; 2023 Nov 20.
Article in English | MEDLINE | ID: mdl-37982782

ABSTRACT

Theoretically, purpose serves as a basic dimension of healthy psychological functioning and an important protective factor from psychopathology. Theory alone, however, is insufficient to answer critical questions about human behavior and functioning; we require empirical evidence that explores the parameters of purpose with respect to measurement, prediction, and modification. Here, we provide empirically supported insights about how purpose can operate as a beneficial outcome (e.g., marker of well-being), a predictor or mechanism that accounts for benefits that a person derives (such as from an intervention), or a moderator that offers insight into when benefits arise. Advancing the study of purpose requires careful consideration of how purpose is conceptualized, manipulated, and measured across the lifespan. Our aim is to help scientists understand, specify, and conduct high-quality studies of purpose in life. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

5.
Suicide Life Threat Behav ; 53(6): 968-980, 2023 12.
Article in English | MEDLINE | ID: mdl-37638764

ABSTRACT

INTRODUCTION: Social anxiety is associated with elevated suicidal ideation (SI). One potential explanation is that socially anxious persons experience frequent interpersonal stressors that elicit SI. Longitudinal designs with temporal ordering are needed to adequately test this hypothesis. Therefore, this study leveraged a longitudinal design combining trait and daily reports. METHODS: Two hundred eleven community adult participants with elevated levels of depression and/or social anxiety completed social anxiety and SI measures at baseline and again at a 1.5-month follow-up. Between these assessments, participants completed a 14-day diary study that assessed three forms of interpersonal distress: unfavorable social comparisons, perceived barriers to seeking social support, and loneliness. RESULTS: As predicted, simple mediation models revealed that baseline social anxiety had a significant indirect effect on SI severity at 1.5 months postbaseline via unfavorable social comparisons (indirect effect: ß = 0.07, p < 0.05) and barriers to seeking support (indirect effect: ß = 0.08, p < 0.05); however, social anxiety did not have a significant indirect effect on SI severity through loneliness. CONCLUSION: Study results are consistent with the proposition that increases in interpersonal distress may explain socially anxious persons' vulnerability to SI. Implications of these findings for the research, assessment, and treatment of suicidality in social anxiety are discussed.


Subject(s)
Depression , Suicidal Ideation , Adult , Humans , Anxiety , Social Support , Loneliness , Risk Factors
6.
JCO Clin Cancer Inform ; 7: e2300015, 2023 06.
Article in English | MEDLINE | ID: mdl-37279409

ABSTRACT

PURPOSE: Remote symptom monitoring (RSM) using electronic patient-reported outcomes enables patients with cancer to communicate symptoms between in-person visits. A better understanding of key RSM implementation outcomes is crucial to optimize efficiency and guide implementation efforts. This analysis evaluated the association between the severity of patient-reported symptom alerts and time to response by the health care team. METHODS: This secondary analysis included women with stage I-IV breast cancer who received care at a large academic medical center in the Southeastern United States (October 2020-September 2022). Symptom surveys with at least one severe symptom alert were categorized as severe. Response time was categorized as optimal if the alert was closed by a health care team member within 48 hours. Odds ratios (ORs), predicted probabilities, and 95% CIs were estimated using a patient-nested logistic regression model. RESULTS: Of 178 patients with breast cancer included in this analysis, 63% of patients identified as White and 85% of patients had a stage I-III or early-stage cancer. The median age at diagnosis was 55 years (IQR, 42-65). Of 1,087 surveys included, 36% reported at least one severe symptom alert and 77% had an optimal response time by the health care team. When compared with surveys that had no severe symptom alerts, surveys with at least one severe symptom alert had similar odds of having an optimal response time (OR, 0.97; 95% CI, 0.68 to 1.38). The results were similar when stratified by cancer stage. CONCLUSION: Response times to symptom alerts were similar for alerts with at least one severe symptom compared with alerts with no severe symptoms. This suggests that alert management is being incorporated into routine workflows and not prioritized based on disease or symptom alert severity.


Subject(s)
Breast Neoplasms , Nurses , Humans , Female , Adult , Middle Aged , Aged , Breast Neoplasms/diagnosis , Breast Neoplasms/therapy , Palliative Care , Surveys and Questionnaires
7.
Cogn Emot ; 37(3): 371-377, 2023.
Article in English | MEDLINE | ID: mdl-37132217

ABSTRACT

Much of the scientific work on emotion regulation has examined strategies in isolation. Now that we have a better understanding of emotion regulatory strategy use and frequency, there is an opportunity to explore new psychological territory. As a starting point, we illustrate how a highly touted strategy, cognitive reappraisal, supercharges a critical component of well-being: purpose in life. We also examine how purpose in life offers a framework to better understand when and how cognitive reappraisal is adaptive. Examining emotion regulation in the context of a sense of purpose in life opens portals to new questions and testable hypotheses. We end with a reconsideration of emotion regulation flexibility over hyper specialization on singular strategies such as reappraisal. Our aim is to inspire research that examines how emotion regulation facilitates or hinders important elements of the good life, as well as how elements of well-being inform regulation choice and success.


Subject(s)
Emotional Regulation , Emotions , Humans , Emotions/physiology , Emotional Regulation/physiology , Cognition/physiology
8.
J Affect Disord ; 329: 285-292, 2023 05 15.
Article in English | MEDLINE | ID: mdl-36801422

ABSTRACT

BACKGROUND: Stress generation theory suggests that people engage in certain behaviors that causally generate "dependent" stressful life events. Stress generation has primarily been studied in the context of depression with limited consideration of anxiety. People with social anxiety exhibit maladaptive social and regulatory behaviors that may uniquely generate stress. METHOD: Across two studies, we examined if people with elevated social anxiety experienced more dependent stressful life events than those lower in social anxiety. On an exploratory basis, we examined differences in perceived intensity, chronicity, and self-blame of stressful life events. As a conservative test, we examined whether observed relationships held after covarying depression symptoms. Community adults (Ns = 303; 87) completed semi-structured interviews about recent stressful life events. RESULTS: Participants with higher social anxiety symptoms (Study 1) and social anxiety disorder (SAD; Study 2) reported more dependent stressful life events than those with lower social anxiety. In Study 2, healthy controls rated dependent events as less impactful than independent events; those with SAD rated dependent and independent events as equally impactful. Regardless of social anxiety symptoms, participants placed greater blame on themselves for the occurrence of dependent than independent events. LIMITATIONS: Life events interviews are retrospective and preclude conclusions about short-term changes. Mechanisms of stress generation were not assessed. CONCLUSIONS: Results provide initial evidence for the role of stress generation in social anxiety that may be distinct from depression. Implications for assessing and treating unique and shared features of affective disorders are discussed.


Subject(s)
Depression , Phobia, Social , Adult , Humans , Depression/psychology , Stress, Psychological/psychology , Retrospective Studies , Anxiety/psychology , Phobia, Social/psychology
9.
JCO Oncol Pract ; 18(12): e1943-e1952, 2022 12.
Article in English | MEDLINE | ID: mdl-36306496

ABSTRACT

PURPOSE: Despite evidence of clinical benefits, widespread implementation of remote symptom monitoring has been limited. We describe a process of adapting a remote symptom monitoring intervention developed in a research setting to a real-world clinical setting at two cancer centers. METHODS: This formative evaluation assessed core components and adaptations to improve acceptability and fit of remote symptom monitoring using Stirman's Framework for Modifications and Adaptations. Implementation outcomes were evaluated in pilot studies at the two cancer centers testing technology (phase I) and workflow (phase II and III) using electronic health data; qualitative evaluation with semistructured interviews of clinical team members; and capture of field notes from clinical teams and administrators regarding barriers and recommended adaptations for future implementation. RESULTS: Core components of remote symptom monitoring included electronic delivery of surveys with actionable symptoms, patient education on the intervention, a system to monitor survey compliance in real time, the capacity to generate alerts, training nurses to manage alerts, and identification of personnel responsible for managing symptoms. In the pilot studies, while most patients completed > 50% of expected surveys, adaptations were identified to address barriers related to workflow challenges, patient and clinician access to technology, digital health literacy, survey fatigue, alert fatigue, and data visibility. CONCLUSION: Using an implementation science approach, we facilitated adaptation of remote symptom monitoring interventions from the research setting to clinical practice and identified key areas to promote effective uptake and sustainability.


Subject(s)
Patient Reported Outcome Measures , Humans , Surveys and Questionnaires , Pilot Projects
10.
J Affect Disord ; 314: 34-43, 2022 10 01.
Article in English | MEDLINE | ID: mdl-35803391

ABSTRACT

BACKGROUND: Most people who survive suicide attempts neither re-attempt suicide nor die by suicide. Research on suicide attempt survivors has primarily focused on negative endpoints (e.g., increased suicide risk) rather than positive outcomes. One important outcome is psychological well-being (PWB), defined as positive functioning across emotional, intrapersonal, and interpersonal domains. We compared PWB among US military veterans with (i.e., attempt survivors) and without (i.e., non-attempters) a history of suicide attempt(s) using data from three nationally representative cohorts. METHODS: Each US veteran cohort (Cohort1: N = 3148; Cohort2: N = 1474; Cohort3: N = 4042) completed measures of suicidality (e.g., attempt history), character strengths (e.g., curiosity, optimism), psychological symptoms (e.g., depression), and indicators of PWB (e.g., happiness). t-Tests were conducted to examine group differences in PWB; hierarchical regressions were conducted to examine suicide attempt status as a predictor of PWB controlling for symptoms and demographics. Multivariable regressions were conducted to identify predictors of PWB among attempt survivors. RESULTS: In each cohort, reported PWB was markedly lower among suicide attempt survivors than non-attempters (ds = 0.9-1.2), even after adjusting for mental health symptoms. Individual differences in PWB were observed, with a subset of suicide attempt survivors reporting higher PWB levels than non-attempters (1.4-7.4 %). Curiosity and optimism were positively associated with PWB among suicide attempt survivors (rs = 0.60-0.78). LIMITATIONS: Data were cross-sectional, limiting inferences about causation and directionality of associations. CONCLUSIONS: Findings highlight diminished PWB as an important and understudied concern among veteran attempt survivors. Collectively, our findings underscore the importance of considering PWB in the research, assessment, and treatment of suicidality.


Subject(s)
Suicide, Attempted , Veterans , Emotions , Humans , Risk Factors , Suicidal Ideation , Suicide, Attempted/psychology , Survivors , Veterans/psychology
11.
Behav Ther ; 53(4): 571-584, 2022 07.
Article in English | MEDLINE | ID: mdl-35697423

ABSTRACT

Bisexual, pansexual, and queer (bi+) individuals are at increased risk for depression and anxiety. These disparities are hypothesized to be due to the unique, minority-specific stressors that they experience. Prior research supports that bi+ stressors are associated with depression and anxiety, but nearly all studies have been cross-sectional, limiting our understanding of how experiencing bi+ stress influences individuals' levels of depression and anxiety as they occur in their day-to-day lives. To address this gap, we examined the daily associations between bi+ stressors (discrimination, internalized stigma, rejection sensitivity, and identity concealment) and depressed/anxious mood in a 28-day diary study. Participants were 208 bi+ individuals who completed daily measures of bi+ stressors and depressed/anxious mood. We tested unlagged (same-day) and lagged (next-day) associations, and we also tested whether internalized stigma, rejection sensitivity, and identity concealment functioned as mechanisms underlying the daily associations between discrimination and depressed/anxious mood. Participants reported higher depressed/anxious mood on days when they reported higher discrimination, internalized stigma, rejection sensitivity, and identity concealment. There were significant unlagged indirect effects of discrimination on depressed and anxious mood via internalized stigma and rejection sensitivity, and there was also a significant unlagged indirect effect of discrimination on anxiety via identity concealment. However, none of the lagged associations were significant. Results suggest that bi+ stress is related to same-day, but not next-day, depressed/anxious mood. The nonsignificant lagged associations could reflect that bi+ individuals are using adaptive coping skills in response to bi+ stress, or that other experiences throughout the day have stronger influences on next-day mood.


Subject(s)
Bisexuality , Sexual and Gender Minorities , Adult , Bisexuality/psychology , Cross-Sectional Studies , Humans , Minority Groups/psychology , Sexual Behavior/psychology , Stress, Psychological/psychology
12.
Behav Ther ; 53(4): 600-613, 2022 07.
Article in English | MEDLINE | ID: mdl-35697425

ABSTRACT

People with social anxiety disorder (SAD) are at increased risk for alcohol-related problems. Most research exploring social anxiety and alcohol use has examined negative drinking consequences, with less consideration of positive consequences-namely positive social experiences-that may reinforce alcohol use. In this daily diary study, we examined how adults diagnosed with SAD (N = 26) and a psychologically healthy control group (N = 28) experienced positive drinking consequences in naturally occurring drinking episodes during the study period. For 14 consecutive days, participants answered questions about alcohol use, motives for drinking, and positive consequences of drinking. On days when participants drank, those with SAD were more likely than healthy controls to perceive a reduction in anxiety, but the two groups did not differ in their likelihood of experiencing positive social drinking consequences. For both groups, on days when they were more motivated to drink to enhance social experiences (affiliation motives) or cope with distress (coping motives), they were more likely to obtain positive consequences from drinking. Compared to controls, participants with SAD endorsed stronger trait and daily coping motives (anxiety-coping, social anxiety-coping, and depression-coping). Results are discussed in the context of reinforcement mechanisms that may maintain social anxiety and alcohol use.


Subject(s)
Phobia, Social , Adaptation, Psychological , Adult , Alcohol Drinking , Anxiety , Humans , Motivation
13.
J Abnorm Psychol ; 130(5): 468-489, 2021 Jul.
Article in English | MEDLINE | ID: mdl-34472884

ABSTRACT

Judgments about the self compared to internalized standards are central to theoretical frameworks of social anxiety. Yet, empirical research on social comparisons-how people view themselves relative to others-and social anxiety is sparse. This research program examines the nature of everyday social comparisons in the context of social anxiety across 2 experience-sampling studies containing 8,396 unique entries from 273 adults. Hypotheses and analyses were preregistered with the Open Science Foundation (OSF) prior to data analysis. Study 1 was a 3-week daily diary study with undergraduates, and Study 2 was a 2-week ecological momentary assessment (EMA) study with a clinical sample of adults diagnosed with social anxiety disorder (SAD) and a psychologically healthy comparison group. In both studies, social anxiety was associated with less favorable, more unstable social comparisons. In both studies, favorable social comparisons were associated with higher positive affect and lower negative affect and social anxiety. In both studies, social comparisons and momentary affect/social anxiety were more strongly linked in people with elevated trait social anxiety/SAD compared to less socially anxious participants. Participants in Study 2-even those with SAD-made more favorable social comparisons when they were with other people than when alone. Taken together, results suggest that social anxiety is associated with unfavorable, unstable self-views that are linked to compromised well-being. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Ecological Momentary Assessment , Phobia, Social , Adult , Anxiety , Anxiety Disorders , Humans , Social Comparison
14.
J Anxiety Disord ; 84: 102474, 2021 12.
Article in English | MEDLINE | ID: mdl-34509949

ABSTRACT

Quality contact with other people serves as a reliable mood enhancement strategy. We wondered if the emotional benefits of socializing are present even for those with a psychological disorder defined by social distress and avoidance: social anxiety disorder (SAD). We conducted two ecological momentary assessment (EMA) studies and analyzed 7243 total surveys. In both studies, community adults diagnosed with SAD and healthy controls received five surveys each day for 2 weeks. Consistent with research on positivity deficits in SAD, between-person analyses in both studies suggest that, on average, participants with SAD reported lower positive and higher negative affect in social and non-social situations than healthy controls. Within-person analyses, however, revealed that in both studies participants with SAD and healthy controls reported higher positive affect when with others than when alone; no differences were found for negative affect for those with SAD. The difference in positive affect between social and nonsocial situations was smaller for participants with SAD in Study 1, suggesting that people with SAD may experience diminished reward responding when socializing. Our results suggest that even those with a mental illness defined by interpersonal distress can and do derive positive emotions from social interactions.


Subject(s)
Phobia, Social , Adult , Anxiety , Ecological Momentary Assessment , Emotions , Happiness , Humans , Social Behavior
15.
J Posit Psychol ; 16(2): 272-281, 2021.
Article in English | MEDLINE | ID: mdl-34239597

ABSTRACT

People with social anxiety disorder (SAD) display maladaptive attitudes towards emotions. In this experience-sampling study, we explored the extent to which people with SAD viewed anxiety and pain as an impediment to pursuing personal strivings and deriving meaning in life. Participants were adults diagnosed with SAD and a control comparison group who completed baseline questionnaires and daily surveys for 14 consecutive days. People with SAD perceived anxiety and pain as interfering with progress towards their strivings to a greater degree than healthy controls. Perception of emotion-related goal interference was inversely associated with daily meaning. This relationship was moderated by diagnostic group such that there was a strong, inverse association with daily meaning in life for people with SAD; for controls, no association was found. Results suggest that negative beliefs about the value of anxiety and pain are pronounced in people with SAD and may impede derivation of meaning in life.

16.
Emotion ; 21(5): 1000-1012, 2021 Aug.
Article in English | MEDLINE | ID: mdl-33829837

ABSTRACT

Much is known about the types of strategies people use to regulate emotions. Less is known about individual differences that influence emotion regulation strategy selection. In this study, we tested the moderating role of negative emotion differentiation (NED; i.e., the ability to label and describe subtle differences among negative emotions) on the relationship between the intensity of stressful daily events and the strategies used to regulate distress arising from these events. Prior research shows that NED is associated with low endorsement of disengagement emotion regulation (e.g., substance use), but less is known about the link to engagement regulation (e.g., problem-solving, seeking social support). Participants were college students (N = 502) completing a 30-day daily diary survey for each of four college years. We preregistered hypotheses that 1) the intensity of each day's most stressful event would be associated with greater use of disengagement and engagement regulation strategies, and 2) people higher in NED would be less likely to use disengagement and more likely to use engagement strategies when highly stressed. Results suggest that higher stress intensity is associated with greater use of all regulation strategies. Greater NED is associated with less use of disengagement regulation strategies, whereas NED was unrelated to engagement regulation strategies and did not moderate the relationship between stress and engagement strategies. The majority of hypothesized moderation effects of NED were nonsignificant, prompting a reconsideration of whether, when, and how NED plays a role in stress responding. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Emotional Regulation , Emotions , Humans , Problem Solving , Social Support , Students
17.
Emotion ; 21(4): 842-855, 2021 Jun.
Article in English | MEDLINE | ID: mdl-32191093

ABSTRACT

This study examines relationships between emotion beliefs and emotion regulation strategy use among people with social anxiety disorder (SAD) and a psychologically healthy control group. Using experience-sampling methodology, we tested group differences in 2 types of emotion beliefs (emotion control values and emotion malleability beliefs) and whether emotion beliefs predicted trait and daily use of cognitive reappraisal and emotion suppression. People with SAD endorsed higher emotion control values and lower emotion malleability beliefs than did healthy controls. Across groups, emotion control values were positively associated with suppression (but unrelated to reappraisal), and emotion malleability beliefs were negatively associated with suppression and positively associated with reappraisal. We also addressed 2 exploratory questions related to measurement. First, we examined whether trait and state measures of emotion regulation strategies were related to emotion control values in different ways and found similar associations across measures. Second, we examined whether explicit and implicit measures of emotion control values were related to daily emotion regulation strategy use in different ways-and found that an implicit measure was unrelated to strategy use. Results are discussed in the context of growing research on metaemotions and the measurement of complex features of emotion regulation. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Attitude , Emotional Regulation , Phobia, Social/psychology , Adult , Ecological Momentary Assessment , Female , Humans , Male , Middle Aged , Young Adult
18.
Emotion ; 21(3): 595-606, 2021 Apr.
Article in English | MEDLINE | ID: mdl-31944786

ABSTRACT

Understanding how individuals with varying levels of social anxiety respond to daily positive events is important. Psychological processes that increase positive emotions are being widely used as strategies to not only enhance well-being but also reduce the symptoms and impairment tied to negative emotional dispositions and conditions, including excessive social anxiety. At present, it is unclear whether and how levels of social anxiety impact the psychological benefits derived from momentary positive events. We used ecological momentary assessment to examine the impact of trait social anxiety on momentary changes in emotions, sense of belonging, and social approach versus avoidance motivation following positive events in daily life. Over the course of a week, people with elevated social anxiety experienced greater momentary anxiety and social avoidance motivation and lower momentary happiness and sense of belonging on average. Despite these impairments, individuals with elevated social anxiety experienced greater psychological benefits-in the form of reduced anxiety and motivation to avoid social situations, and an increased sense of belonging-following positive events during the past hour that were rated as particularly intense. This pattern of findings was not specific to social anxiety, with evidence of similar effects for other forms of internalizing psychopathology (general anxiety and depression). These observations detail circumstances in which individuals with social anxiety, and other emotional disturbances, can thrive-creating potentially important targets for intervention. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Affect/physiology , Anxiety/psychology , Ecological Momentary Assessment/standards , Emotions/physiology , Adult , Female , Humans , Male
19.
Front Endocrinol (Lausanne) ; 12: 777831, 2021.
Article in English | MEDLINE | ID: mdl-34975753

ABSTRACT

Human environmental exposures to toxicants, such as polychlorinated biphenyls (PCBs), increase oxidative stress and disease susceptibility. Such exposures during pregnancy and/or nursing have been demonstrated to adversely affect offspring health outcomes. Nuclear factor erythroid-2-related factor 2 (Nrf2) regulates the antioxidant response and is involved in the detoxification of coplanar PCBs, like PCB126. The purpose of this study was to investigate glucose tolerance and body composition in PCB-exposed offspring expressing or lacking Nrf2. We hypothesized that offspring lacking Nrf2 expression would be more susceptible to the long-term health detriments associated with perinatal PCB exposure. During gestation, whole-body Nrf2 heterozygous (Het) and whole-body Nrf2 knockout (KO) mice were exposed to vehicle or PCB126. Shortly after birth, litters were cross-fostered to unexposed dams to prevent PCB exposure during nursing. Offspring were weaned, and their body weight, body composition, and glucose tolerance were recorded. At two months of age, PCB exposure resulted in a significant reduction in the average body weight of offspring born to Nrf2 Het dams (p < 0.001) that primarily arose from the decrease in average lean body mass in offspring (p < 0.001). There were no differences in average body weight of PCB-exposed offspring born to Nrf2 KO dams (p > 0.05), and this was because offspring of Nrf2 KO dams exposed to PCB126 during pregnancy experienced a significant elevation in fat mass (p = 0.002) that offset the significant reduction in average lean mass (p < 0.001). Regardless, the lack of Nrf2 expression in the offspring themselves did not enhance the differences observed. After an oral glucose challenge, PCB-exposed offspring exhibited significant impairments in glucose disposal and uptake (p < 0.05). Offspring born to Nrf2 Het dams exhibited these impairments at 30 min and 120 min, while offspring born to Nrf2 KO dams exhibited these impairments at zero, 15, 30, 60 and 120 min after the glucose challenge. Again, the interactions between offspring genotype and PCB exposure were not significant. These findings were largely consistent as the offspring reached four months of age and demonstrate that the lack of offspring Nrf2 expression does not worsen the metabolic derangements caused by in utero PCB exposure as we expected. Future directions will focus on understanding how the observed maternal Nrf2 genotypic differences can influence offspring metabolic responses to in utero PCB exposure.


Subject(s)
Energy Metabolism/genetics , NF-E2-Related Factor 2/genetics , Polychlorinated Biphenyls/toxicity , Prenatal Exposure Delayed Effects , Animals , Animals, Newborn , Body Composition/genetics , Diabetes Mellitus/chemically induced , Diabetes Mellitus/genetics , Diabetes Mellitus/metabolism , Disease Susceptibility/chemically induced , Female , Genotype , Male , Mice , Mice, Inbred ICR , Mice, Knockout , Pregnancy , Prenatal Exposure Delayed Effects/chemically induced , Prenatal Exposure Delayed Effects/genetics , Prenatal Exposure Delayed Effects/metabolism
20.
Behav Ther ; 51(5): 728-738, 2020 09.
Article in English | MEDLINE | ID: mdl-32800301

ABSTRACT

One potential factor that could influence how individuals with at least moderate symptoms of depression cope with upsetting events in their daily lives is the beliefs that these individuals hold about whether emotions are malleable or fixed. The current study adopted an experience sampling approach to examine how the beliefs about emotion's malleability related to daily positive and negative affect and daily emotion regulation efforts among individuals with at least moderate symptoms of depression (N = 84). Results demonstrated that individuals having at least moderate symptoms of depression who held more malleable beliefs about emotions reported decreased negative affect both overall during the day and specifically in response to daily upsetting events. Additionally, these individuals who held more malleable beliefs about their emotions also reported more daily use of cognitive reappraisal to regulate their emotions in response to upsetting daily events. Results from the current study extend previous work examining the relationship between emotion malleability beliefs, emotional experiences, and emotion regulation to examine these relationships in people who are moderately depressed as they navigate the emotional landscape of their daily lives.


Subject(s)
Adaptation, Psychological , Emotional Regulation , Emotions , Ecological Momentary Assessment , Humans
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