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The Ruminant Telomere-to-Telomere (RT2T) Consortium.

Kalbfleisch, Theodore S; McKay, Stephanie D; Murdoch, Brenda M; Adelson, David L; Almansa-Villa, Diego; Becker, Gabrielle; Beckett, Linda M; Benítez-Galeano, María José; Biase, Fernando; Casey, Theresa; Chuong, Edward; Clark, Emily; Clarke, Shannon; Cockett, Noelle; Couldrey, Christine; Davis, Brian W; Elsik, Christine G; Faraut, Thomas; Gao, Yahui; Genet, Carine; Grady, Patrick; Green, Jonathan; Green, Richard; Guan, Dailu; Hagen, Darren; Hartley, Gabrielle A; Heaton, Mike; Hoyt, Savannah J; Huang, Wen; Jarvis, Erich; Kalleberg, Jenna; Khatib, Hasan; Koepfi, Klaus-Peter; Koltes, James; Koren, Sergey; Kuehn, Christa; Leeb, Tosso; Leonard, Alexander; Liu, George E; Low, Wai Yee; McConnell, Hunter; McRae, Kathryn; Miga, Karen; Mousel, Michelle; Neibergs, Holly; Olagunju, Temitayo; Pennell, Matt; Petry, Bruna; Pewsner, Mirjam; Phillippy, Adam M.

Nat Genet ; 56(8): 1566-1573, 2024 Aug.

Article in English | MEDLINE | ID: mdl-39103649

ABSTRACT

Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously 'invisible' parts of the genome and allow comparative analyses of complete genomes across entire clades. We present here an open collaborative effort, termed the 'Ruminant T2T Consortium' (RT2T), that aims to generate complete diploid assemblies for numerous species of the Artiodactyla suborder Ruminantia to examine chromosomal evolution in the context of natural selection and domestication of species used as livestock.

Subject(s)

Ruminants , Telomere , Telomere/genetics , Animals , Ruminants/genetics , Evolution, Molecular , Genome/genetics , Selection, Genetic , Phylogeny , Diploidy

ABSTRACT

Subject(s)

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