Preoperative MR imaging for ESMO-ESGO-ESTRO classification of endometrial cancer.

OBJECTIVE: To retrospectively investigate whether magnetic resonance imaging (MRI) findings could contribute to predict histologic type, tumor grade and lymphovascular space invasion (LVSI) to improve preoperative assessment of endometrial cancer using the European Society for Medical Oncology (ESMO) European Society for Radiotherapy & Oncology (ESTRO) and European Society of Gynecological Oncology (ESGO) classification. METHODS: Between January 2008 and August 2014, 104 women (mean age, 65±11 [SD] years; range, 32-84 years) with International Federation of Gynecology and Obstetrics (FIGO) stage I endometrial cancer underwent preoperative MRI of the pelvis. Two independent readers evaluated tumor heterogeneity and measured tumor size on T2-weighted, diffusion-weighted and T1-weighted images obtained after gadolinium chelate administration at 2minutes. The apparent diffusion coefficient (ADC) was generated from pixel ADC from the whole tumor volume. RESULTS: A short axis>24mm on MRI was associated with histopathologic type 2, grade 3 tumor and presence of LVSI (P<0.01). There were no significant differences in minimum, mean and maximum ADC between presence/absence of LVSI. In 9.1% women (9/99), the accuracy of the ESMO-ESGO-ESTRO classification with the inclusion of the MRI short-axis criterion was higher than that of the conventional ESMO classification to predict high-risk recurrence endometrial cancer (P=0.02). CONCLUSION: Tumor size reflects histologic type, tumor grade and LVSI in endometrial cancer. FIGO stage 1 endometrial cancer>24mm should be classified preoperatively in the high-intermediate or high-risk recurrence risk groups.

Severe hemoptysis: From diagnosis to embolization.

Severe hemoptysis is life-threatening to patients because of the asphyxia it causes. The diagnosis and treatment are therefore urgent and chest imaging is essential. Multidetector CT-angiography provides an exhaustive non-invasive assessment which includes localization, mechanisms, causes and severity of the hemoptysis. It is an invaluable step in preparation for endovascular treatment which is the first line invasive therapy, particularly with bronchial arteriography embolization in the majority of cases (over 90%) and erosion or rupture of the pulmonary artery in less than 10% of cases. Hemoptysis control is achieved in 65 to 92% of cases depending on the cause.

Risk of sural nerve injury during lateral distal Achilles tendinoscopy: a cadaver study.

BACKGROUND: The risk of damage to cutaneous sensory nerves located near portals has been evaluated for both conventional arthroscopy and extra-articular posterior ankle endoscopy. The objective of the anatomic study reported here was to assess the risk of injury to the sural nerve or lateral calcaneal nerve while using the distal lateral portal for the Achilles tendinoscopy procedure described by Vega et al. in 2008. MATERIALS AND METHODS: We dissected the sural nerve and its branch, the lateral calcaneal nerve, of 13 human cadaver ankles in the prone position. We defined P as the point where the Achilles peritendon was opened during the distal lateral approach used for the study technique. P was adjacent to the lateral edge of the Achilles tendon, 2 cm proximal to the postero-superior edge of the calcaneal tuberosity. T was defined as the attachment site of the most lateral fibres of the Achilles tendon to the postero-superior edge of the calcaneal tuberosity. We evaluated the origin of the lateral calcaneal nerve relative to T and we measured the shortest distances separating P from the sural nerve and lateral calcaneal nerve. RESULTS: A lateral calcaneal nerve was identified in 10 (77%) ankles and originated a mean of 39.1mm (range, 25.0-65.0mm) proximal to T. P was at a mean distance from the sural nerve of 12.3mm (range, 5.0-18.0mm) and from the lateral calcaneal nerve of 6.8mm (range, 4.0-9.0mm). The median difference between these two distances was statistically significant (P=0.002). DISCUSSION: While using the distal lateral portal for Achilles tendinoscopy, the lateral calcaneal nerve is at greater risk for injury than is the sural nerve. LEVEL OF EVIDENCE: Level IV. Anatomic Study.

Cruciate-sacrificing total knee arthroplasty and insert design: A radiologic study of sagittal laxity.

INTRODUCTION: Ultracongruent inserts avoid some of the drawbacks of central spine postero-stabilized inserts. However, early wear has been reported, and may be due to increased sagittal laxity. The principal objective of the present study was to compare sagittal laxity in rotating platform total knee replacements (TKR) according to insert design: ultracongruent versus central spine. The principal hypothesis was that insert design influences global sagittal laxity. MATERIAL AND METHODS: A retrospective comparative study recruited 3 consecutive series of patients treated for primary osteoarthritis of the knee, with a minimum 1 year's follow-up. The UC series comprised 35 knees in 34 patients, receiving a Total Knee Triathlon™ (Stryker Orthopaedics, Mahwah, NJ) TKR with ultracongruent insert, at a mean 2.0 years' follow-up. The UC+ series comprised 36 knees in 34 patients, receiving the BalanSys™ (Mathys Ltd, Bettlach, Switzerland) TKR with ultracongruent insert, at a mean 2.5 years' follow-up; in this model, the anterior edge of the insert is higher than in the UC series ("deep-dish" design). The PS series comprised 43 knees in 40 patients, receiving a Total Knee Triathlon™ (Stryker Orthopaedics, Mahwah, NJ) TKR with central spine posterior stabilization, at a mean 1.5 years' follow-up. The principal assessment criterion was sagittal laxity at 90° flexion as measured by the Telos Stress Device® (Metax GmbH, Hungen, Germany). RESULTS: Sagittal laxity did not significantly differ between the UC and UC+ series: mean 8.2mm (range: 0-19.5mm) and 8.4mm (4.5-15.8mm), respectively. Sagittal laxity in the PS series was significantly less: 1.4mm (0.2-3.9) (P<0.0001). CONCLUSION: Sagittal laxity was greater in ultracongruent than central spine posterior stabilized TKR. This anteroposterior movement may induce polyethylene wear. The ideal degree of sagittal laxity for ultracongruent inserts remains to be determined. LEVEL OF EVIDENCE: IV - retrospective study.