1.
J Rheumatol
; 23(9): 1550-2, 1996 Sep.
Article
in English
| MEDLINE
| ID: mdl-8877923
ABSTRACT
OBJECTIVE: To examine the efficacy and steroid sparing potential of methotrexate (MTX) in the treatment of polymyalgia rheumatica (PMR) without giant cell arteritis. METHODS: 43 patients with PMR were treated with MTX 7.5 mg/wk for 3 months. This dose was raised to 10 and finally 12.5 mg/wk MTX if the desired response was not obtained. RESULTS: No patient benefitted clinically or statistically from treatment with MTX. CONCLUSION: MTX is of no benefit in the treatment of PMR.
Subject(s)
Methotrexate/therapeutic use , Polymyalgia Rheumatica/drug therapy , Aged , Aged, 80 and over , Blood Sedimentation/drug effects , Drug Therapy, Combination , Female , Humans , Male , Middle Aged , Polymyalgia Rheumatica/blood , Prednisone/therapeutic use , Treatment Outcome
2.
Arthritis Rheum
; 38(12): 1862-3, 1995 Dec.
Article
in English
| MEDLINE
| ID: mdl-8849363