ABSTRACT
A considerable incidence of colonic strictures after oncologic low anterior resections has been reported. The present paper describes a colonic stricture 5 years after the surgery, and not related to radiotherapy, that required a challenging differential diagnosis with local recurrence of rectal cancer. The role of endoscopy in the management of this condition is discussed.
Subject(s)
Colitis, Ischemic/complications , Colonic Diseases/diagnosis , Colonic Diseases/etiology , Intestinal Obstruction/diagnosis , Intestinal Obstruction/etiology , Postoperative Complications/diagnosis , Postoperative Complications/etiology , Rectum/surgery , Aged , Humans , Male , Time FactorsABSTRACT
Existe una incidencia no despreciable de lesiones de colon deorigen isquémico tras resecciones anteriores bajas por cáncer.Presentamos un caso de estenosis isquémica de colon, no relacionadacon radioterapia, a los 5 años de la cirugía. Se discute la dificultaddel diagnóstico diferencial con recidiva tumoral, así como elimportante papel que desempeña la endoscopia en el abordaje deestos pacientes
A considerable incidence of colonic strictures after oncologiclow anterior resections has been reported. The present paper describesa colonic stricture 5 years after the surgery, and not relatedto radiotherapy, that required a challenging differential diagnosiswith local recurrence of rectal cancer. The role of endoscopyin the management of this condition is discussed
Subject(s)
Humans , Male , Aged , Colitis, Ischemic/complications , Colonic Diseases/diagnosis , Colonic Diseases/etiology , Intestinal Obstruction/diagnosis , Intestinal Obstruction/etiology , Postoperative Complications/diagnosis , Postoperative Complications/etiology , Rectum/surgery , Time FactorsABSTRACT
We report the case of thyroid dysfunction that developed in a 36-year-old female patient who required combination therapy with interferon and ribavirine for chronic hepatitis C. Firstly, she suffered a hyperthyroidism followed by a hypothyroidism stage requiring thyroxine replacement therapy. Nevertheless, combination treatment was not discontinued, reaching a sustained biochemical and virological response. The pathogenesis of autoimmune diseases in patients with Hepatitis C virus infection and interferon therapy is not clear, but usually these disorders are reversible and only require supervision and treatment if clinical or laboratory abnormalities are present.
Subject(s)
Antiviral Agents/adverse effects , Hepatitis C/complications , Interferon-alpha/adverse effects , Thyroid Diseases/chemically induced , Antiviral Agents/therapeutic use , Female , Hepatitis C/drug therapy , Humans , Interferon alpha-2 , Interferon-alpha/therapeutic use , Middle Aged , Recombinant Proteins , Thyroid Diseases/complicationsABSTRACT
Describimos un caso de alteración de la función tiroidea que se presentó en una mujer de 36 años que requirió tratamiento combinado con interferón y ribavirina para su hepatitis crónica C. En primer lugar, presentó un hipertiroidismo seguido por un hipotiroidismo que requirió tratamiento con tiroxina. Sin embargo, el tratamiento combinado no fue suspendido, alcanzando una respuesta mantenida bioquímica y virológica. La patogenia de las enfermedades autoinmunes en pacientes con infección por el virus C de la hepatitis tratados con interferón no está clara, pero generalmente estos trastornos son reversibles y sólo requiere supervisión y tratamiento si se presentaran anormalidades clínicas o bioquímicas (AU)
