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1.
Bioelectron Med ; 9(1): 7, 2023 Mar 31.
Article in English | MEDLINE | ID: mdl-36998060

ABSTRACT

BACKGROUND: There is emerging evidence that the nervous system regulates immune and metabolic alterations mediating Metabolic syndrome (MetS) pathogenesis via the vagus nerve. This study evaluated the effects of transcutaneous auricular vagus nerve stimulation (TAVNS) on key cardiovascular and inflammatory components of MetS. METHODS: We conducted an open label, randomized (2:1), two-arm, parallel-group controlled trial in MetS patients. Subjects in the treatment group (n = 20) received 30 min of TAVNS with a NEMOS® device placed on the cymba conchae of the left ear, once weekly. Patients in the control group (n = 10) received no stimulation. Hemodynamic, heart rate variability (HRV), biochemical parameters, and monocytes, progenitor endothelial cells, circulating endothelial cells, and endothelial micro particles were evaluated at randomization, after the first TAVNS treatment, and again after 8 weeks of follow-up. RESULTS: An improvement in sympathovagal balance (HRV analysis) was observed after the first TAVNS session. Only patients treated with TAVNS for 8 weeks had a significant decrease in office BP and HR, a further improvement in sympathovagal balance, with a shift of circulating monocytes towards an anti-inflammatory phenotype and endothelial cells to a reparative vascular profile. CONCLUSION: These results are of interest for further study of TAVNS as treatment of MetS.

2.
Article in English | LILACS, Index Psychology - journals | ID: biblio-845946

ABSTRACT

Depression is a common disorder among health professionals, in particular in nurses. GOALS: Verify the presence and intensity of depression symptoms; analyze triggering factors and evaluate the perception of nurses regarding their psychological distress and their working conditions. METHOD: Exploratory and descriptive study, quantitative, performed with Family Health Strategy nurses in the city of São Paulo, interviews by means of a semi-structured questionnaire using three psychometric scales, statistical analysis by Fisher’s exact test and the t-Student test. RESULTS: 59 nurses participated and an expressive majority presented depression symptoms without realizing they were ill. The key factors mentioned were related to their working conditions. CONCLUSION: A high prevalence of depression symptoms was observed due to working conditions.


Depressão é transtorno comum entre profissionais da saúde, em específico nos de Enfermagem. OBJETIVOS: Verificar a presença e intensidade da sintomatologia depressiva; analisar os fatores desencadeantes e avaliar a percepção dos enfermeiros sobre seu sofrimento psíquico e as condições de trabalho. MÉTODO: Estudo exploratório e descritivo, quantitativo, realizado com enfermeiros da Estratégia de Saúde da Família em município de São Paulo. Entrevistas por meio de questionário semiestruturado, utilizadas três escalas psicométricas. Análise estatística pelo teste exato de Fisher e teste t-Student. RESULTADOS: Participaram 59 enfermeiros, expressiva maioria apresentou sintomatologia depressiva, não se percebiam doentes. Principais fatores apontados estavam relacionados às condições do trabalho. CONCLUSÃO: Observou-se alta prevalência de sintomas depressivos devido às condições de trabalho.


Depresión es trastorno común entre profesionales de la salud, en específico en los de Enfermería. OBJETIVOS: Verificar la presencia e intensidad de la sintomatología depresiva; analizar los factores desencadenantes y evaluar la percepción de los enfermeros sobre su sufrimiento psíquico y las condiciones de trabajo. MÉTODO: Estudio exploratorio y descriptivo, cuantitativo, realizado con enfermeros de la Estrategia de Salud de la Familia en el municipio de São Paulo. Entrevistas por medio de cuestionario semiestruturado, utilizadas tres escalas psicométricas. Análisis estadístico por la prueba exacta de Fisher y prueba t-Student. RESULTADOS: Participaron 59 enfermeros, expresiva mayoría presentó sintomatología depresiva, no se percibían enfermos. Principales factores apuntados estaban relacionados a las condiciones del trabajo. CONCLUSIÓN: Se observó alta superioridad de síntomas depresivos debido a las condiciones de trabajo.


Subject(s)
Humans , Male , Female , Depression , National Health Strategies , Nurses , Occupational Health , Professional Practice
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