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1.
Am J Obstet Gynecol MFM ; 6(4): 101318, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38417552

ABSTRACT

BACKGROUND: Outpatient term preinduction cervical ripening with mechanical agents has been associated with reduced length of stay, decreased cesarean delivery rates, low maternal and neonatal complications, and increased incidence of vaginal delivery within 24 hours. OBJECTIVE: This study aimed to demonstrate equivalent efficacy between synthetic hygroscopic dilators and the single-balloon catheter for outpatient cervical ripening. STUDY DESIGN: This randomized control equivalence trial compared synthetic hygroscopic dilators with the 30-mL silicone single-balloon catheter in primiparous and multiparous patients undergoing labor induction. The primary outcome was time from admission to delivery, with a prespecified 3-hour margin of equivalence. The secondary objectives were patient outcomes and perspectives. RESULTS: Between March 1, 2019, and May 31, 2021, 1605 patients met the screening criteria, and 174 patients completed the study. The mean admission-to-delivery time was equivalent at 18.01 hours for the dilator group vs 17.55 hours for the balloon group (P=.04). The cesarean delivery rate of primiparous patients was similar at 28.1% with dilators vs 29.7% with the balloon. The groups had similar median cervical dilation and pain scores on insertion and admission. Overall patient satisfaction was high, 92.8% with dilators vs 96.2% with the balloon. The balloon group had significantly higher rates of early admission and device expulsion. CONCLUSION: Although the enrollment goal was not met, our study suggests that synthetic hygroscopic dilators and the single-balloon catheter for outpatient cervical ripening are both efficacious with similar time from admission to delivery, pain scores, and patient satisfaction with the procedure.


Subject(s)
Cervical Ripening , Labor, Induced , Humans , Female , Cervical Ripening/drug effects , Pregnancy , Adult , Labor, Induced/methods , Cesarean Section/methods , Cesarean Section/statistics & numerical data , Patient Satisfaction , Dilatation/methods , Dilatation/instrumentation , Ambulatory Care/methods , Outpatients/statistics & numerical data
2.
Article in English | MEDLINE | ID: mdl-36981757

ABSTRACT

Recent research on the subject of information-gathering processes among pregnant women has revealed a shift towards online sources. Health professionals' knowledge about sources of information has been shown to improve the understanding and counseling of patients. The objective of this study was to create an overview of all types of sources relevant to information gathering and to put their role and perception into perspective. METHODS: A total of 249 women were included in this study and recruited over a period of one month at the University Hospital of Zurich (USZ). Exclusion criteria included cases of fetal demise and late abortions. The survey on information-gathering processes was divided into three stages: pregnancy, birth, and puerperium. The different sources of information were compared based on women's characteristics. RESULTS: The response rate was 78% (n = 197). The main findings include a significant difference in information gathering based on varying levels of education, with women at the lowest educational level using the Internet the least during pregnancy (p = 0.029). During puerperium, significant differences could be observed in the involvement of the gynecologist. Primipara women as well as women of lower educational levels contacted their gynecologist less in contrast to multipara women (p = 0.006) and women of higher educational levels (p = 0.011). Overall, health professionals were considered to be the most important source of information. CONCLUSIONS: This study demonstrates that parity and educational level influence the information-gathering process. As the most important source for information gathering, health professionals must use this advantage to better assist their patients in accessing reliable information.


Subject(s)
Parturition , Pregnant Women , Pregnancy , Female , Humans , Pregnant Women/psychology , Postpartum Period , Parity , Surveys and Questionnaires
3.
Horm Mol Biol Clin Investig ; 41(3)2019 Nov 06.
Article in English | MEDLINE | ID: mdl-31693493

ABSTRACT

Background Ovarian carcinoma is a poor prognosis cancer mainly due to its late diagnosis. Its incidence is relatively low but mortality is high. The symptomatology is only slightly specific, which complicates diagnostic management. It would therefore be interesting to be able to establish a diagnosis as early as possible in order to improve the prognosis of patients suffering from ovarian cancer. Materials and methods Currently, the combination of an ultrasound examination with a cancer antigen (CA)-125 assay is the most effective diagnostic technique, but not already admitted as a screening method. Therefore, we realized an exhaustive analysis of the most important studies in the last 15 years, in order to find new approaches in ovarian cancer screening. Results The age for initiating screening and its frequency are issues that are not fully resolved. The false positives and morbidity that result from screening are currently notable limitations. Conclusions The latest data do not support effective screening in the general population.


Subject(s)
Carcinoma/diagnostic imaging , Early Detection of Cancer/standards , Ovarian Neoplasms/diagnostic imaging , Practice Guidelines as Topic , CA-125 Antigen/blood , Carcinoma/blood , Carcinoma/epidemiology , Early Detection of Cancer/statistics & numerical data , False Positive Reactions , Female , Humans , Membrane Proteins/blood , Ovarian Neoplasms/blood , Ovarian Neoplasms/epidemiology , Ultrasonography/methods , Ultrasonography/standards
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