1.
J Natl Cancer Inst
; 66(5): 849-58, 1981 May.
Article
in English
| MEDLINE
| ID: mdl-6939929
ABSTRACT
Bronchi, pancreatic ducts, and colons from adult human were maintained as xenografts in congenitally athymic nude N:NIH(S) mice for 715, 145, and 89 days, respectively. After an ischemic crisis and revascularization of the human tissue, the epithelium regenerated to a normal differentiated morphology. The long-term survival of normal adult human epithelial tissues as xenografts provides model systems for the study of the interactions of chemical and/or physical carcinogens with human tissues.
Subject(s)
Bronchi/immunology , Colon/immunology , Graft Survival , Pancreatic Ducts/immunology , Animals , Bronchi/pathology , Bronchi/transplantation , Carcinogens , Colon/pathology , Colon/transplantation , Disease Models, Animal , Humans , Mice , Mice, Nude , Neoplasms/chemically induced , Pancreatic Ducts/pathology , Pancreatic Ducts/transplantation , Pilot Projects , Time Factors , Transplantation, Heterologous
2.
Biochim Biophys Acta
; 304(3): 660-8, 1973 May 28.
Article
in English
| MEDLINE
| ID: mdl-4726851