Subject(s)
Humans , Male , Adult , Heart Diseases/diagnostic imaging , Hemangiosarcoma/mortality , Hemangiosarcoma/prevention & control , Echocardiography/methods , Cardiac Tamponade/diagnosis , Echocardiography, Transesophageal/methods , Pericardiocentesis/methods , Positron Emission Tomography Computed Tomography/methodsABSTRACT
ABSTRACT: A 67-year-old man with rapidly neurologic deterioration and 15 kg weight loss in 2 months was extensively evaluated by several medical specialties and conventional image examinations, with no diagnostic definition. 18F-FDG PET/CT was performed, showing glycolytic hypermetabolism in the hippocampus, cerebral hypometabolism with posterior temporoparietal pattern, multiple cervical and supraclavicular lymph nodes, and mediastinal hypermetabolic and enlarged lymph nodes, suggesting paraneoplastic limbic encephalitis, Alzheimer dementia, and lymphoma. Lymph node biopsy resulted in small cell lung carcinoma. The patient presented rapid clinical deterioration and died.
Subject(s)
Fluorodeoxyglucose F18 , Limbic Encephalitis/complications , Limbic Encephalitis/diagnostic imaging , Lung Neoplasms/complications , Positron Emission Tomography Computed Tomography , Small Cell Lung Carcinoma/complications , Aged , Humans , MaleABSTRACT
A 35-year-old woman with rectal neuroendocrine tumor, Ki-67 proliferation index less than 2%, and a mediastinal mass on CT postoperatively was referred for restaging with PET/CT Ga-DOTATATE. The examination showed uptake on the pelvic lymph node and mediastinal mass. Because of differences in lesions' SUVs and clinical presentation, the hypothesis of lymphoma for the mediastinal mass was raised, and F-FDG PET/CT was performed, which showed glycolytic hypermetabolism in the mediastinal mass and absence of hypermetabolism in pelvic lymph nodes. Transthoracic biopsy of the mass revealed atypical large-cell lymphoid proliferation, and immunohistochemistry study was compatible with Castleman disease.
