Propiedades psicométricas de un instrumento para evaluar signos y síntomas relacionados con VIH / Psychometric properties of an instrument to evaluate HIV-related signs and symptoms

Objetivo: analizar las propiedades psicométricas del instrumento The Revised Sign and Symptom Checklist for HIV (SSC-HIVrev) en función del contexto, las poblaciones y las muestras en que se ha aplicado el instrumento.Método: revisión bibliográfica realizada en las bases CINAHL, PubMed y Scielo de artículos publicados entre 2001 y 2019 en idioma inglés, español o portugués aplicando los conceptos de búsqueda “HIV” AND “Signs and aymptoms” según correspondiese en cada base. Se excluyeron aquellos que no utilizasen el cuestionario SSC-HIVrev o no reportasen sus propiedades psicométricas. Se evaluaron y analizaron los resultados por parte de dos investigadoras. Se extrajeron las distintas propiedades psicométricas.Resultados: se localizaron 1.124 registros de los cuales 16 cumplieron los criterios de selección. Los alfa de Cronbach reportados tras evaluar la consistencia interna oscilaron entre 0,76 y 0,97. Tres estudios reportaron validez de contenido mediante expertos en distintos contextos, uno validez de constructo (capacidad de explicación del 73% de la varianza estableciendo once factores) y uno indicó sensibilidad al cambio adecuada en las escalas de fatiga y depresión.Conclusión: se encontraron valores confiables de alfa de Cronbach (superiores a 0,70) en los distintos contextos donde se ha aplicado el SSC-HIVrev. La validez de contenido, de constructo, discriminante y la sensibilidad al cambio están escasamente estudiadas.(AU)

Objective: to analyze the psychometric properties of The Revised Sign and Symptom Checklist for HIV (SSC-HIVrev) based on the setting, populations and samples where this instrument has been applied.Method: a bibliographic review conducted in the CINAHL, PubMed and Scielo databases, including articles published between 2001 and 2019 in English, Spanish or Portuguese, using the search concepts “HIV” AND “Signs and symptoms”, as relevant in each database. Those articles not using the SSC-HIVrev questionnaire or not reporting their psychometric properties were excluded. Results were assessed and analyzed by two researchers; the different psychometric properties were extracted.Results: in total 1.124 records were located, and 16 of these met the selection criteria. After evaluating internal consistency, the Cronbach’s Alpha values reported ranged between 0.76 and 0.97. Three studies reported content validity through experts in different settings, one reported construct validity (ability of explaining 73% of the variance by determining eleven factors), and one stated adequate sensitivity to change in the fatigue and depression scales.Conclusion: reliable Cronbach’s Alpha values (> 0.70) were found in the different settings where the SSC-HIVrev was applied. There are limited studies about the content validity, construct validity, discriminant validity, and sensitivity to change.(AU)

Association between pelvic floor disorder symptoms and QoL scores with depressive symptoms among pelvic organ prolapse patients.

BACKGROUND: There is no consensus on the relationship between depressive symptoms (DS) and pelvic organ prolapse (POP) symptoms and quality of life (QoL). Our hypothesis was that women with DS and POP have worse symptoms and QoL than those without DS and POP. AIM: Our aim was to compare two groups of POP patients, those with depressive symptoms and those without, and evaluate the association of symptoms and QoL. MATERIALS AND METHODS: This planned report is part of a prospective study evaluating the impact of pessary use among symptomatic POP patients. Patients were evaluated by POP quantification (POP-Q), pelvic ultrasound (US), voiding diaries, stress test, pad test, Pelvic Floor Distress Inventory (PFDI-20), Prolapse QoL (P-QoL) and the Goldberg Health Questionnaire (GHQ-12) (psychological health screening for DS when score ≥5). A sample size of 78 patients was required to demonstrate a 50-point difference in the global PFDI-20 score with 80% power and 95% probability. RESULTS: Ninety-one women with POP were included. GHQ-12 was positive in 47 (51.6%) patients. No differences were found in POP-Q, pad and stress test between those with a positive GHQ-12 and those without. However, GHQ-12 was associated with higher PFDI-20 scores and higher scores in seven of nine P-QoL domains. GHQ-12 persisted as an independent risk factor for worse P-QoL scores after multivariable analysis. CONCLUSION: A 'positive' screening for DS was associated with worse PFDI-20 and P-QoL scores despite no difference in objective measurements. It may be that depressed patients interpret their symptoms differently.

Validation of the Spanish-language version of the Prolapse Quality of Life questionnaire in Chilean women.

INTRODUCTION AND HYPOTHESIS: The Prolapse Quality of Life (P-QOL) questionnaire is a specific health-related quality of life (HRQL) instrument to assess the impact of POP on women. It has been validated in English-speaking women and to date has been translated into several other languages. However, currently there is no Spanish translation of the P-QOL questionnaire. The aim of this study was to translate the P-QOL questionnaire into Spanish and to assess its feasibility, validity, and reliability. METHODS: Following a forward- and back-translation of the original English P-QOL questionnaire into Spanish language, the translated questionnaire was reviewed by a group of patients as well as an expert panel to assess its comprehensibility. In this cross-sectional study women with POP symptoms were recruited from a tertiary referral teaching hospital. Women were defined as symptomatic if they report feeling a lump/bulge/pressure in the vagina. The Spanish translated P-QOL questionnaire was self-administered to all women. Reliability, content, and construct validity were evaluated using the Cronbach's alpha coefficient, ANOVA, and Spearman's correlation tests. RESULTS: One hundred and twenty-eight women were studied. There were no missing items. The Cronbach's alpha ranged from 0.626 to 0.866 across domains, demonstrating the good reliability of the Spanish P-QOL. The severity of symptoms was related to the worst quality of life, but the severity of POP was not related to poorer QoL. CONCLUSIONS: The Spanish translated version of the P-QOL is a reliable, consistent and valid instrument to assess symptom severity and QoL impact in Chilean women with POP.