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1.
ESC Heart Fail ; 8(6): 4409-4424, 2021 12.
Article in English | MEDLINE | ID: mdl-34523254

ABSTRACT

The improvement in left ventricular assist device (LVAD) technology and scarcity of donor hearts have increased dramatically the population of the LVAD-supported patients and the probability of those patients to present to the emergency department with expected and non-expected device-related and patient-device interaction complications. The ageing of the LVAD-supported patients, mainly those supported with the 'destination therapy' indication, increases the risk for those patients to suffer from other co-morbidities common in the older population. In this second part of the trilogy on the management of LVAD-supported patients for the non-LVAD specialist healthcare provider, definitions and structured approach to the LVAD-supported patient presenting to the emergency department with bleeding, neurological event, pump thrombosis, chest pain, syncope, and other events are presented. The very challenging issue of declaring death in an LVAD-supported patient, as the circulation is artificially preserved by the device despite no other signs of life, is also discussed in detail.


Subject(s)
Cardiology , Heart Failure , Heart Transplantation , Heart-Assist Devices , Emergency Service, Hospital , Health Personnel , Heart Failure/epidemiology , Heart-Assist Devices/adverse effects , Humans , Tissue Donors
2.
ESC Heart Fail ; 8(6): 4394-4408, 2021 12.
Article in English | MEDLINE | ID: mdl-34519177

ABSTRACT

The accepted use of left ventricular assist device (LVAD) technology as a good alternative for the treatment of patients with advanced heart failure together with the improved survival of the LVAD-supported patients on the device and the scarcity of donor hearts has significantly increased the population of LVAD-supported patients. The expected and non-expected device-related and patient-device interaction complications impose a significant burden on the medical system exceeding the capacity of the LVAD implanting centres. The ageing of the LVAD-supported patients, mainly those supported with the 'destination therapy' indication, increases the risk for those patients to experience comorbidities common in the older population. The probability of an LVAD-supported patient presenting with medical emergency to a local emergency department, internal, or surgical ward of a non-LVAD implanting centre is increasing. The purpose of this trilogy is to supply the immediate tools needed by the non-LVAD specialized physician: ambulance clinicians, emergency ward physicians, general cardiologists, internists, anaesthesiologists, and surgeons, to comply with the medical needs of this fast-growing population of LVAD-supported patients. The different issues discussed will follow the patient's pathway from the ambulance to the emergency department and from the emergency department to the internal or surgical wards and eventually to the discharge home from the hospital back to the general practitioner. In this first part of the trilogy on the management of LVAD-supported patients for the non-LVAD specialist healthcare provider, after the introduction on the assist devices technology in general, definitions and structured approach to the assessment of the LVAD-supported patient in the ambulance and emergency department is presented including cardiopulmonary resuscitation for LVAD-supported patients.


Subject(s)
Heart Transplantation , Heart-Assist Devices , Health Personnel , Heart-Assist Devices/adverse effects , Hospitals , Humans , Tissue Donors
3.
Sleep Breath ; 16(3): 855-63, 2012 Sep.
Article in English | MEDLINE | ID: mdl-21938436

ABSTRACT

OBJECTIVES: There is no consensus in the literature about the impact of complete denture wear on obstructive sleep apnea (OSA). The goal of this randomized clinical study was to assess if complete denture wear during sleep interferes with the quality of sleep. MATERIALS AND METHODS: Elderly edentulous OSA patients from a complete denture clinic were enrolled and received new complete dentures. An objective sleep analysis was determined with polysomnography performed at the sleep laboratory for all patients who slept either with or without their dentures. RESULTS: Twenty-three patients (74% females) completed the study with a mean age of 69.6 years and a mean body mass index of 26.7 kg/m(2). The apnea and hypopnea index (AHI) was significantly higher when patients slept with dentures compared to without (25.9 ± 14.8/h vs. 19.9 ± 10.2/h; p > 0.005). In the mild OSA group, the AHI was significantly higher when patients slept with the dentures (16.6 ± 6.9 vs. 8.9 ± 2.4; p < 0.05), while in moderate to severe OSA patients, the AHI was not significantly different when sleeping with dentures (.30.8 ± 15.6 vs. 25.7 ± 7.5; p = 0.2). The supine AHI in mild patients was related to a higher increase in AHI while wearing dentures (12.7 ± 8.4/h vs. 51.9 ± 28.6/h; p < 0.001). A limitation of the study is that the mild OSA patients had a higher BMI when compared to the moderate to severe OSA patients. Ten out of 14 patients who preferred to sleep with their upper and lower dentures showed an increase in their AHI while wearing dentures to sleep. CONCLUSIONS: Contrary to previous studies, we found that OSA patients may experience more apneic events if they sleep with their dentures in place. Specifically, in mild OSAS patients, the use of dentures substantially increases the AHI especially when in the supine position.


Subject(s)
Denture, Complete , Sleep Apnea, Obstructive/epidemiology , Sleep Apnea, Obstructive/etiology , Sleep , Aged , Aged, 80 and over , Cross-Sectional Studies , Disorders of Excessive Somnolence/epidemiology , Disorders of Excessive Somnolence/etiology , Female , Humans , Male , Middle Aged , Mouth, Edentulous/epidemiology , Mouth, Edentulous/therapy , Polysomnography , Risk Factors , Surveys and Questionnaires
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