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Intern Med ; 59(5): 733-737, 2020.
Article in English | MEDLINE | ID: mdl-32115520

ABSTRACT

A 74-year-old man underwent intravesical bacillus Calmette-Guerin (BCG) therapy for bladder cancer and later presented with lower left back pain. Magnetic resonance imaging of the spine showed high signal intensity, diagnosed as a cystic lesion in the epidural and bilateral intestinal psoas muscle. A computed tomography-guided needle biopsy and histological examination revealed bacteria from the family Mycobacteriaceae, and Mycobacterium bovis was identified using multiplex polymerase chain reaction. If lower back pain appears in a patient who has undergone BCG therapy, it is necessary to test for tuberculous spondylitis. In addition, QuantiFERON is useful for the differential diagnosis of M. bovis BCG infection.


Subject(s)
Adjuvants, Immunologic/adverse effects , Antineoplastic Agents, Immunological/adverse effects , BCG Vaccine/adverse effects , Spondylitis/chemically induced , Tuberculosis, Spinal/chemically induced , Urinary Bladder Neoplasms/drug therapy , Adjuvants, Immunologic/administration & dosage , Administration, Intravesical , Aged , Antineoplastic Agents, Immunological/administration & dosage , BCG Vaccine/administration & dosage , Humans , Image-Guided Biopsy , Magnetic Resonance Imaging/adverse effects , Male , Mycobacterium bovis , Tomography, X-Ray Computed/adverse effects
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