ABSTRACT
Telomere biology disorders (TBD) are a complex set of inherited illnesses characterized by short telomeres. Dyskeratosis congenita (DC), which is now considered a severe TBD phenotype, is characterized by reticulated pigmentary changes, nail dystrophy, premalignant oral leukoplakia, and systemic involvement. This case describes a 2-year-old female with reticulated pigmentary changes and Terry's nails who was found to have a TERT variant and short telomeres; she lacked other mucocutaneous and systemic features of TBD. This report describes a unique clinical presentation of TBD and highlights the importance of upholding suspicion for TBD in individuals with limited or subtle features of classic DC.
ABSTRACT
are that the contents of this article are their own original unpublished findings. Title: Comparison of potential contact allergens in best-selling adult and baby cleansers Authors: Jayden Galamgam1 MD, Sasan D Noveir2 BA, Carol E Cheng1 MD Affiliations: 1Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA, 2 David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA Corresponding Author: Jayden Galamgam MD, Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, Email: jgalamgam@mednet.ucla.edu.
Subject(s)
Allergens , Humans , Allergens/adverse effects , Dermatitis, Allergic Contact/etiology , Adult , Infant , Detergents/adverse effectsSubject(s)
DEET , Insect Repellents , Insect Repellents/adverse effects , Humans , DEET/adverse effects , Child , Pyrazines/adverse effects , Female , PiperidinesABSTRACT
Many baby cleansers are promoted as hypoallergic products; however, these claims are not typically validated. This study assessed the 50 best-selling baby cleansers from online retailer Amazon for potential allergens. We found that the presence of most marketing claims, including "hypoallergenic" or "allergy-tested," did not correlate with the number of potential allergens in a cleanser. Furthermore, the total number of marketing claims of a cleanser was positively correlated with the number of allergens, highlighting the discordance between marketing claims and allergen content in baby cleansers.
Subject(s)
Allergens , Humans , Allergens/adverse effects , Infant , Prevalence , Dermatitis, Allergic Contact/etiology , Detergents/adverse effects , Infant Care/methodsABSTRACT
Social media platforms such as TikTok allow patients to exchange and share health information. In this study, we sought to understand how teenagers and young adults utilize TikTok to engage with acne and isotretinoin information. Analysis of the top 50 TikTok videos on an isotretinoin trend demonstrated over 18-million likes and 137-thousand comments. Most videos focused on before and after improvement in acne severity while video comments primarily discussed side effects and personal anecdotes. Dermatologists should be aware of trending content on social media to better understand how youth patients and patient's families may receive medical information regarding isotretinoin outside of dermatology clinics.