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1.
Nat Commun ; 9(1): 1089, 2018 03 14.
Article in English | MEDLINE | ID: mdl-29540718

ABSTRACT

Information transport and processing by pure magnonic spin currents in insulators is a promising alternative to conventional charge-current-driven spintronic devices. The absence of Joule heating and reduced spin wave damping in insulating ferromagnets have been suggested for implementing efficient logic devices. After the successful demonstration of a majority gate based on the superposition of spin waves, further components are required to perform complex logic operations. Here, we report on magnetization orientation-dependent spin current detection signals in collinear magnetic multilayers inspired by the functionality of a conventional spin valve. In Y3Fe5O12|CoO|Co, we find that the detection amplitude of spin currents emitted by ferromagnetic resonance spin pumping depends on the relative alignment of the Y3Fe5O12 and Co magnetization. This yields a spin valve-like behavior with an amplitude change of 120% in our systems. We demonstrate the reliability of the effect and identify its origin by both temperature-dependent and power-dependent measurements.

2.
Sci Total Environ ; 533: 290-6, 2015 Nov 15.
Article in English | MEDLINE | ID: mdl-26172596

ABSTRACT

Levels of organohalogen compounds (PCBs, chlordane, PBB 153, PBDEs, HCB) were determined in adipose tissue, liver, kidney and muscle of four polar bears which swam and/or drifted to Iceland in extremely malnourished condition. Since the colonization in the 9th century polar bears have been repeatedly observed in Iceland. However, in recent years three of the animals have clearly left their natural habitat in poor condition in May or June, i.e. at the end of the major feeding season. The fourth bear is believed to have drifted with melting ice to North-Eastern Iceland in mid-winter. The concentrations of the POPs were within the range or higher than the typical concentrations measured in polar bears from the East Greenland population. In addition to the targeted compounds, we tentatively detected Dechlorane 602 and its potential hydrodechlorinated Cl11-metabolite in all samples. Moreover, a polychlorinated compound which partly co-eluted with PCB 209 was detected in all liver samples but not in adipose tissue, kidney or muscle. The mass spectrum of the potential metabolite did not allow determining its structure. Polar bears are good swimmers and can reach Iceland from the ice edge of East Greenland within a few days. Potential reasons for the swims are briefly discussed.


Subject(s)
Chlordan/metabolism , Environmental Monitoring , Environmental Pollutants/metabolism , Hexachlorobenzene/metabolism , Polychlorinated Biphenyls/metabolism , Ursidae/metabolism , Adipose Tissue/metabolism , Animals , Greenland , Iceland , Swimming
3.
Respir Care ; 56(8): 1115-21, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21801578

ABSTRACT

BACKGROUND: Diffusing capacity of the lung for carbon monoxide (D(LCO)) can be affected by abnormal hemoglobin (Hb) or carboxyhemoglobin (COHb) levels. Predicted D(LCO) can be adjusted to reflect abnormal Hb or COHb levels. Until recently, blood sampling was required to determine Hb and COHb levels, but a new pulse oximeter, the Masimo RAD-57, can measure Hb and COHb noninvasively. We hypothesized that there would be no significant difference between the invasive and noninvasive Hb and COHb measurements for adjusting D(LCO). METHODS: In patients referred to our university hospital for D(LCO) testing, we simultaneously took arterial blood gas samples and measured Hb and COHb with the RAD-57 (SpHb and SpCOHb, respectively). We analyzed the paired values and the Hb-adjusted and COHb-adjusted predicted D(LCO) values with t tests and Bland-Altman plots. We compared the differences in predicted D(LCO) to a clinical threshold of 3 mL/min/mm Hg. RESULTS: SpHb differed from Hb measured via arterial blood analysis (12.1 ± 2.4 g/dL vs 13.3 ± 2.1 g/dL, P < .001). SpCOHb did not differ significantly from COHb (ie, measured via arterial blood analysis) (2.1 ± 4.0 vs 2.5 ± 2.3, P = .25), but there was wide variability. There were small but statistically significant differences in the adjusted predicted D(LCO), depending on whether blood or pulse oximetry values were used. Predicted D(LCO) adjusted for both Hb and COHb was 22.5 ± 4.8 mL/min/mm Hg measured with the RAD-57 and 23.5 ± 4.5 mL/min/mm Hg via arterial blood analysis (P < .001). The limits of agreement for pulse oximetry adjusted D(LCO) exceeded the clinical threshold of 3 mL/min/mm Hg for Hb adjustments and combined Hb + COHb. Predicted D(LCO) values differed by > 3 mL/min/mm Hg in 17% of patients. CONCLUSIONS: Pulse oximetry may be of limited usefulness for adjusting either predicted or measured D(LCO) values, but might be useful to screen patients for invasive testing, particularly if the D(LCO) is close to the lower limit of normal.


Subject(s)
Carbon Monoxide/analysis , Carboxyhemoglobin/analysis , Lung/metabolism , Oximetry/instrumentation , Pulmonary Diffusing Capacity/instrumentation , Equipment Design , Follow-Up Studies , Humans , Male , Middle Aged , Reproducibility of Results
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