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1.
Toxicon ; 230: 107151, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37187226

ABSTRACT

The trend of replacing antimicrobials as growth promoters in animal nutrition is growing. Functional oils emerge as an alternative because of their richness in bioactive compounds and bioavailability. The present study aims to evaluate the fatty acid profile, antioxidant capacity, composition of phenolic compounds, and toxic capacity in Wistar rats of pracaxi oil (Pentaclethra macroloba). DDPH (2,2-diphenyl-1-picrylhydrazyl), FRAP (Ferric Reducing Antioxidant Power), and ABTS (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) were performed to assess antioxidant capacity. The composition of phenolic compounds was determined by specific reagents. For the evaluation of subchronic oral toxicity, 40 Wistar albino rats (20 males and 20 females) were randomized into 10 groups with different levels of pracaxi oil administered orally. The doses administered were 0, 300, 600, 1200 and 2400 mg/kg (Group 1 to 5 females and Group 6 to 10 males). The animals were submitted to evaluations described in the OECD manual (Guide 407). The analytical results showed that pracaxi oil has different fatty acids in its chemical composition: oleic, linoleic, arachidic, and behenic acids, which account for more than 90% of its composition. In a smaller percentage, lauric acid (0.17%), myristic (0.09%), palmitic (1.49%), stearic (3.45%), and linolenic acid (1.39%) were also found. According to the results of the antioxidant tests, pracaxi oil has a high antioxidant capacity and is a product with a high presence of phenolic compounds. Regarding the toxicity assessment, there were no alterations in the clinical signs and weight of organs. However, in histology, there were mild alterations of a possible toxic process with the increase in the oil dose. This research is extremely valuable since pracaxi oil is a product with little information about its potential use in animal nutrition.


Subject(s)
Antioxidants , Plant Oils , Animals , Rats , Fatty Acids , Plant Oils/chemistry , Rats, Wistar
2.
Anim Sci J ; 92(1): e13539, 2021.
Article in English | MEDLINE | ID: mdl-33682281

ABSTRACT

The objective is to evaluate different bedding materials, including dehydrated grass, on performance and carcass yield and verify the physicochemical and microbiological characteristics of materials. The completely randomized experiment comprised 1,080 chicks in a 3 × 2 factorial design with three levels of dehydrated grass (0%, 25%, and 50%) and two bedding materials (rice husks and shavings). Total microorganism count and physicochemical characteristics, surface temperature of birds, and performance of birds were analyzed up to 42 days of age, when birds were slaughtered, and carcass yield was evaluated. The inclusion of grass showed a higher microbiological count after 1 day, stabilizing with materials after 28 days. The inclusion of 50% of dehydrated grass resulted in a higher surface bed temperature at 42 days. Inclusions above 25% of grass have a lower density and a greater water retention capacity, pH, moisture, and total nitrogen, in addition to a lower FDA in its structure. The highest ammonia emissions occurred with the inclusion of 25% of grass. The inclusion of dehydrated grass did not affect performance and carcass yield, favoring feed conversion at the initial stages. The inclusion of grass can replace up to 25% of shavings without harming physicochemical parameters of materials and birds' performance.


Subject(s)
Bedding and Linens/veterinary , Chickens/growth & development , Poaceae , Ammonia/analysis , Animals , Bedding and Linens/microbiology , Chemical Phenomena , Desiccation , Humidity , Hydrogen-Ion Concentration , Male , Nitrogen/analysis , Oryza , Temperature , Water/analysis
3.
Braz. j. vet. res. anim. sci ; 48(2): 141-146, 2011. tab
Article in Portuguese | LILACS | ID: lil-654023

ABSTRACT

Em dois ensaios experimentais avaliou-se efeito dietético da suplementação de acidificantes sobre o desempenho (ensaio1) e coeficientes de digestibilidade aparente de nutrientes (ensaio 2) em suínos. No ensaio 1, com duração de 42 dias,120 leitões desmamados aos 21 dias foram distribuídos em oit8 blocos experimentais com três leitões por baia, foramaplicados cinco tratamentos, sendo um controle e4quatro com a inclusão de acidificantes. No ensaio 2,0dez leitões compeso médio inicial de 16,4 kg foram distribuídos em dois blocos experimentais, cada um com cinco repetições, sob doistratamentos (ração sem acidificante ou com 1,0% de ácido fumárico). No estudo de desempenho, a adição de ácidofumárico nas rações determinou aumentos no consumo de ração nos períodos de 0 aos 15 dias, 0 aos 32 dias e ganhode peso de 0 aos 42 dias, quando comparado ao tratamento controle. No ensaio 2, a adição de 1,0% de ácido fumáricona ração não alterou os coeficientes de digestibilidade aparente da matéria seca e demais componentes químicos dasdietas. A ausência de diferenças nos coeficientes de digestibilidade aparente dos nutrientes dietéticos com a inclusão doacidificante provavelment, deveu-se ao curto período de avaliação. A inclusão de ácido fumárico nas rações de leitõesdesmamados favoreceu o desempenho dos leitões.


In two experimental assays it was evaluated the diet acidifier supplementation effect on performance (assay 1) and onnutrient apparent digestibility coefficients (assay 2). During 42 days in assay 1, 120 piglets weaned at 21-days years oldwere allotted in8eight experimental block design with3three pigs per experimental unit. The treatments were a controland4four acidified diets. In assay 2,0ten piglets with an average weight of 16,4 kg were allotted in two experimentalblock design receiving two treatments under five replications (control diet without acidifier or supplied with 1,0%fumaric acid). On performance study the fumaric acid inclusion in the diet permitted a feed intake increase from 0 to15 days, and weight gain from 0 to 32 days and from 0 to 42 days. In assay 2, the diet 1,0% of fumaric acid inclusion didnot modified the apparent digestibility coefficients of dry matter and moreover diet chemical compounds. The similarapparent digestibility coefficient of dietetic nutrients with the acidifier inclusio, probabl, occurred due to the shortperiod of evaluation. The fumaric acid inclusion in weaned piglet diets improved performance of piglets.


Subject(s)
Animals , Animal Nutritional Physiological Phenomena , Fumaricum Acidum/administration & dosage , Swine/physiology , Weaning , Diarrhea/veterinary , Digestion/physiology , Weight Gain/physiology
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