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Rev Gastroenterol Mex ; 73(1): 33-5, 2008.
Article in Spanish | MEDLINE | ID: mdl-18792672

ABSTRACT

GIST is the most common mesenchymal tumor of the gastrointestinal tract. The discovery of KIT proto-oncogene mutations in the pathogenesis of this tumor, and the development of imatinib mesylate, a specific inhibitor of KIT tyrosine kinase function have revolutionized the treatment of GIST. We present the clinical case of a patient with an upper digestive bleeding secondary to a jejunal GIST. Therapeutic options are highlighted.


Subject(s)
Gastrointestinal Stromal Tumors/diagnosis , Gastrointestinal Stromal Tumors/surgery , Jejunal Neoplasms/diagnosis , Jejunal Neoplasms/surgery , Humans , Male , Middle Aged , Proto-Oncogene Mas
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