ABSTRACT
The iStent (Glaukos Corporation, Laguna Hills, CA) is a 1-mm, titanium trabecular bypass stent implanted across the inner wall of Schlemm's canal under direct gonioscopy. This study was designed to determine the best modality to identify iStent placement when gonioscopic visualization is not possible. In this in vitro study on a human cadaver eye, ultrasound biomicroscopy (UBM), anterior segment optical coherence tomography (AS-OCT), and B-scan ultrasonography were done to visualize and precisely locate two intentionally misplaced iStents. UBM could localize both intentionally misplaced stents, whereas AS-OCT could not visualize the iStent that was lodged in the sulcus. B-scan ultrasonography was unable to detect either of the stents. UBM may be a useful imaging modality to identify iStent in the anterior or posterior chamber, whereas AS-OCT is limited to detection of stents in the anterior chamber alone. B-scan ultrasonography is unable to identify iStent in either the anterior or posterior chamber.