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1.
Trop Anim Health Prod ; 56(3): 110, 2024 Mar 22.
Article in English | MEDLINE | ID: mdl-38517584

ABSTRACT

The hypothesis was tested that the performance of lactating ewes is affected by the supplementation level and pasture management. Two supplementation levels (0.5 and 1.0% of body weight, BW) and two pasture managements (mowed and non-mowed) were tested. Forty adult ewes (2 years old) with an average weight at lambing of 62.97 ± 7.0 kg (day 0) and an average the body condition score of 2.5 points (day 0) were evaluated. Verminosis was monitored with periodic deworming. The number of eggs per gram of feces (EPG) of ewes at lambing was used as a covariate for performance assessments. Ewes lost an average of 7.5 kg over the 90 days post-partum (12% BW). The weaning rate was 53%. The body condition of the ewes was influenced by the post-partum period. The ewes mobilized their body reserves in the first 30 days of lactation. Mowing management negatively affected the nutritive value of the forage. Supplementation with 0.5% BW was sufficient for nutritional management post-partum. Pasture management (mowed vs. not mowed) cannot prevent post-partum weight loss. Supplementation levels and pasture management altered the morphological and chemical components of the pasture.


Subject(s)
Lactation , Ovum , Sheep , Animals , Female , Postpartum Period , Weaning , Dietary Supplements
2.
Trop Anim Health Prod ; 55(5): 330, 2023 Sep 26.
Article in English | MEDLINE | ID: mdl-37749453

ABSTRACT

Our objective was to evaluate the productive parameters of ewes and their lambs in relation to ewe age and to develop models for predicting lamb weight at birth and weaning in a tropical warm-climate pasture. Individual data were collected from 273 ewes and 273 lambs, between 2013 and 2021. During this period all animals were kept on pastures of Brachiaria brizantha cv. Marandu All lambs in the experiments were supplemented in creep-feeding. A descriptive statistical analysis was performed using the PROC SUMMARY procedure in SAS (SAS University Edition, SAS Institute Inc. Cary, CA, USA). Pearson correlation coefficients between variables were estimated using the PROC CORR procedure in SAS (SAS University Edition, SAS Institute Inc. Cary, CA, USA). Model adjustments and variable selection were performed using PROC REG in SAS (SAS University Edition, SAS Institute Inc. Cary, CA, USA). The STEPWISE option and Mallow's C(p) were used to select the variables included in the equations. Outliers were identified by evaluating the studentized residuals based on the predicted values from the equations. Residual analysis was predicted by regression minus observed values and those that fell outside the range of -2.5 to 2.5 were removed. Several statistics were used to assess the predictability of the equations, including the coefficients of determination (r2) and mean standard error (RMSE). The average ewe age at lambing was 3.4 ± 1.7 years, with an average weight of 56.9 ± 8,9 kg and average body condition score (BCS) of 2,4 ± 0.8 points. The average ewe age at weaning was 51.1 ± 7.9, with average BCS of 1.8 ± 0.8 points. The average lamb at birthing was 3.9 ± 0.9 kg. The average lamb at weaning was 21.0 ± 4.9, with daily gain of 0.2 ± 0.1 kg/day and total gain of 17.1 ± 4.7 kg birth to weaning. The lamb produced by ewe at lambing was 5.3 ± 1.7 kg/ewe. The lamb weaned by ewe at weaning was 28.7 ± 10.8 kg/ewe. The ratios of lamb produced per ewe at birth and at weaning were 0.1 ± 0.03 and 0.6 ± 0.2, respectively. The lamb's birth weight showed a positive linear relationship with the age of the ewe, increasing by 115 g per year of age. The regression equations adjusted for ewe age had maximum points ranging from 4.2 to 5.2, occurring at average age of 4,7 years. The other characteristics showed a quadratic tendency. The results suggest the culling of ewes at five years of age to generate lambs with ideal weight at birth and at weaning raised in warm tropical pastures.


Subject(s)
Brachiaria , Sheep, Domestic , Humans , Sheep , Animals , Female , Birth Weight , Weaning , Models, Theoretical
3.
Trop Anim Health Prod ; 55(2): 109, 2023 Mar 14.
Article in English | MEDLINE | ID: mdl-36917307

ABSTRACT

The objective was to evaluate the effect of the supplementation with natural antioxidants from Yerba mate (Ilex paraguariensis St. Hil.) on the performance, carcass and meat characteristics, and fatty acid profile in meat and fat of Texel × Ile de France lambs kept in Brachiaria-grass pasture. Twenty lambs with a mean age of 90 days and 26.3 kg of BW were distributed in a completely randomized design in two treatments with 10 replicates/treatment: Control-protein-energy supplement based on corn and soybean meal (150 g/kg DM of crude protein) without the addition of natural antioxidant yerba mate and Yerba Mate - energy protein supplement with the addition of yerba mate (110 g/kg DM). There was no treatment effect on animal performance and carcass characteristics. The subcutaneous fat thickness was significantly higher for lambs treated without yerba mate. There was no effect of nutritional treatments on the oxidative markers of lamb meat. The muscle of the animals treated with yerba mate showed a higher concentration of unsaturated and polyunsaturated fatty acids elaidic, linolenic, thymnodonic, docosadienoic, and ceorvonic. The fat of the animals treated with yerba mate showed a higher concentration of palmitoleic acid, linoelaidic acid, heneicosanoic acid, dihomo-γ-linolenic acid, and arachidonic acid. The concentration of polyunsaturated fatty acids was significantly higher in meat and fat of lambs treated with yerba mate. Including yerba mate in the diet of lambs kept on Brachiaria pastures improves the lipid profile of polyunsaturated fatty acids in meat and fat, without altering the performance of the animals.


Subject(s)
Ilex paraguariensis , Animals , Animal Feed/analysis , Antioxidants , Fatty Acids/metabolism , Fatty Acids, Unsaturated , Ilex paraguariensis/metabolism , Meat/analysis , Sheep , Sheep, Domestic/metabolism
4.
Trop Anim Health Prod ; 55(1): 13, 2022 Dec 19.
Article in English | MEDLINE | ID: mdl-36534328

ABSTRACT

The hypothesis tested is that the association of soybean grain and yerba mate as an antioxidant source can increase the concentration of polyunsaturated fatty acids (PUFA) with lower oxidation of milk from lactating ewes reared in tropical pastures. Sixteen ewes were randomly distributed in a 2x2 factorial scheme (with or without yerba mate at 110 g / kg of dry matter (DM); with or without soybean grain at 210 g/kg of DM). Yerba mate intake reduced DM intake, and concentrations of ether extract (EE), protein, lactose, defatted dry extract, density, omega-3 concentrations, and the ratio between saturated/monounsaturated fatty acids (FA), but increased the concentration of monounsaturated FA and the sequestering power of free radicals by DPPH without altering the concentrations of conjugated dienes and the concentrations of substances reactive to thiobarbituric acid in milk. Supplementation with soybean grain decreased the birth weight of the lambs and increased the concentrations of conjugated linoleic acid (CLA), PUFA, omega - 6, omega ratio - 6/omega - 3, and total blood cholesterol. The addition of yerba mate did not influence the oxidative profile of milk. Supplementation with soybean grain improved the FA profile of milk, increasing the concentrations of CLA and PUFA. The results suggest that the association of yerba mate and soybean grain helps to improve the fat quality of milk from ewes raised in tropical pastures, as shown by the enhanced antioxidant activity, although it does not help prevent oxidation of milk rich in PUFA.


Subject(s)
Antioxidants , Ilex paraguariensis , Animals , Female , Antioxidants/metabolism , Dietary Supplements , Edible Grain , Fatty Acids/analysis , Fatty Acids, Unsaturated/analysis , Ilex paraguariensis/chemistry , Lactation , Milk/chemistry , Plant Extracts/chemistry , Sheep , Glycine max
5.
Trop Anim Health Prod ; 53(5): 481, 2021 Sep 25.
Article in English | MEDLINE | ID: mdl-34562171

ABSTRACT

Studies on the rearing of ewe lambs in the Cerrado are scarce, so the objective was to evaluate the effects of protein-energy supplementation with 1.6 and 2.4% BW on the productive and reproductive performance of ewe lambs raised on pastures of Brachiaria brizantha cv. Marandu. Twenty-four Texel ewe lambs, with a mean age of 5 months, were distributed in two treatments with provision of energy protein supplementation at levels of 1.6 and 2.4% BW, formulated for average daily gains of 150 and 200 g/day for ewe lambs weighing 20 kg, respectively. The experimental delineation adopted was the completely randomized design, with fifteen repetitions per treatment. The performance of the ewe lambs was evaluated by weight at the beginning and end of the breeding season (BS), average daily gain (ADG), and total weight gain (TWG). The count of fecal eggs was performed monthly. The evaluation of the ewe lambs reproductive organs took place at 8 months of age. The fertility of the ewe lambs was detected by transrectal ultrasonography at the end of the BS. The supplementation level of 2.4% BW was higher for ADG and TWG; however, it did not influence the other performance characteristics. There was no effect of supplementation on the reproductive characteristics, parasite load, and nutrients of the pasture. Pasture nutrients were influenced by the month of use. Supplementation levels were not effective to ensure the reproductive success of 8-month-old ewe lambs.


Subject(s)
Ovum , Plant Breeding , Animals , Dietary Supplements , Female , Reproduction , Sheep , Sheep, Domestic
6.
Logoped Phoniatr Vocol ; 46(2): 55-62, 2021 Jul.
Article in English | MEDLINE | ID: mdl-32138570

ABSTRACT

PURPOSE: At a worldwide level, suicide is a public health problem that, despite displaying downward trends in several areas of the world, in many countries these rates have increased. One of the elements that contributes to its prevention is an early and dynamic evaluation. Due to this, the objective is to determine the association between acoustic parameters of voice and speech (F0, F1, F2, F3, dB, and Jitter) and suicidal ideation arousal amongst some university students from the city of Temuco, Chile. METHODS: Attending to this issue, a cross-sectional design study was conducted through a non-probabilistic sampling of sixty 18- and 19-year-old adolescents from the city of Temuco, that went through an acoustic evaluation of their voice and speech after taking a test to determine suicidal ideation. Afterwards, data were analyzed through IBM SPSS version 23.0 software (IBM SPSS Statistics, Armonk, NY), by means of exploratory, descriptive, and inferential statistics taking the variable's levels of measurements and the types of distributions into account. RESULTS: The results point out that 30% of the adolescents, from both genders, displayed suicidal ideation. Taking into account the acoustic results of their voice, it is possible to recognize that the fundamental frequency (F0), the formants (F1, F2), and Jitter, are the ones that majorly link to the presence of suicidal ideation, both in women and men (p < .05). The characteristics that describe F3 were only linked to the presence of suicidal ideation in men (p < .05). CONCLUSIONS: It is concluded that the acoustic parameters of voice and speech differ in adolescents with suicidal behavior, opening the possibility of representing a useful tool in the diagnosis of suicide.


Subject(s)
Speech , Suicidal Ideation , Acoustics , Adolescent , Adult , Cross-Sectional Studies , Female , Humans , Male , Pilot Projects , Students , Universities , Voice Quality , Young Adult
7.
ACS Omega ; 5(26): 16003-16009, 2020 Jul 07.
Article in English | MEDLINE | ID: mdl-32656421

ABSTRACT

The application of solid electrolyte reactors for methane oxidation to co-generation of power and chemicals could be interesting, mainly with the use of materials that could come from renewable sources and abundant metals, such as the [6,6'- (2, 2'-bipyridine-6, 6'-diyl)bis (1,3,5-triazine-2, 4-diamine)](nitrate-O)copper (II) complex. In this study, we investigated the optimal ratio between this complex and carbon to obtain a stable, conductive, and functional reagent diffusion electrode. The most active Cu-complex compositions were 2.5 and 5% carbon, which were measured with higher values of open circuit and electric current, in addition to the higher methanol production with reaction rates of 1.85 mol L-1 h-1 close to the short circuit potential and 1.65 mol L-1 h-1 close to the open circuit potential, respectively. This activity was attributed to the ability of these compositions to activate water due to better distribution of the Cu complex in the carbon matrix as observed in the rotating ring disk electrode experiments.

8.
Photomed Laser Surg ; 36(7): 370-376, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29768084

ABSTRACT

OBJECTIVE: This is a randomized, sham-controlled, blind clinical trial that aimed to evaluate the effect of phototherapy on bite force, mandibular range of motion, sensitivity to palpation, and fatigue in the masseter and anterior temporal muscles of young patients when administered before the induction of fatigue. MATERIALS AND METHODS: Fifty-two healthy volunteers aged 18-23 years were randomly allocated to a laser group and sham group. Both groups were submitted to a clinical evaluation to record mandibular range of motion, bite force, muscle sensitivity to palpation, and muscle fatigue. The laser group was then submitted to phototherapy (780 nm, 25 J/cm2, 50 mW, 20 sec, and 1 J per point) on three points of the masseter and one point of the anterior temporal muscle on each side. The sham group was submitted to the same procedure, but with the device switched off. The volunteers were then instructed to chew two pieces of gum (one on each side) for 6 min, with the pace set by a metronome calibrated to 80 bpm, followed by the reevaluation of all variables. The results were submitted to t-test and Wilcoxon test. A significance level of 5% (p < 0.05) was considered in all analyses. RESULTS: No statistically significant intergroup or intragroup differences were found for the variables analyzed. CONCLUSIONS: With the proposed protocol, phototherapy administered before the induction of fatigue did not lead to any changes in bite force and mandibular range of motion, indicating that further studies are needed with different phototherapy dosimetric parameters.


Subject(s)
Masseter Muscle/radiation effects , Muscle Fatigue/radiation effects , Phototherapy , Temporal Muscle/radiation effects , Adolescent , Bite Force , Female , Humans , Male , Mastication , Single-Blind Method , Young Adult
9.
BMJ Open ; 8(5): e018326, 2018 05 05.
Article in English | MEDLINE | ID: mdl-29730613

ABSTRACT

INTRODUCTION: Epidemiological data show that the signs and symptoms of temporomandibular disorder (TMD) start becoming apparent from 6 years of age, and during adolescence these signs and symptoms are similar to those of adults. The present study aims to estimate the direct costs for treatment of chronic muscle pain with photobiomodulation therapy, occlusal splint and placebo in patients with TMD; to evaluate the effectiveness of photobiomodulation therapy and occlusal splint for treatment of muscle pain in patients with TMD; to analyse the cost-effectiveness of the two proposed treatments for pain; and to describe and compare the results of the analyses of these treatments. METHODS AND ANALYSIS: This is a prospective trial of clinical and economic analyses that will include 135 patientswith TMD aged between 15 years and 25 years, randomly assigned to a treatment group: G1 (photobiomodulation), G2 (occlusal splint) and G3 (placebo). The analyses will be based on the cost of each treatment during the 12-month period. The outcome of the analysis of effectiveness will be pain, measured periodically by means of clinical examination of Research Diagnostic Criteria for Temporomandibular Disorders. The cost-effectiveness ratio will be calculated using, as end points, pain and the ratio of the differences in costs between the groups studied. The evaluation of the impact of the treatment on quality of life will be determined by applying the adapted EuroQol-5D. ETHICS AND DISSEMINATION: This protocol has been ethically approved by the local medical ethical committee, protocol number 2.014.339. Results will be submitted to international peer-reviewed journals and presented at international conferences. TRIAL REGISTRATION NUMBER: NCT03096301.


Subject(s)
Chronic Pain/radiotherapy , Low-Level Light Therapy/economics , Low-Level Light Therapy/methods , Temporomandibular Joint Disorders/complications , Adolescent , Adult , Brazil , Cost-Benefit Analysis , Female , Humans , Male , Occlusal Splints , Pain Management , Pain Measurement , Prospective Studies , Quality of Life , Randomized Controlled Trials as Topic , Treatment Outcome , Young Adult
10.
Clinics (Sao Paulo) ; 72(3): 161-170, 2017 Mar.
Article in English | MEDLINE | ID: mdl-28355362

ABSTRACT

OBJECTIVES:: To evaluate the colorimetric change in incisors and canines of adolescents aged 12 to 20 years submitted to at-home whitening and to evaluate satisfaction, sensitivity and discomfort during the procedures through a questionnaire. METHOD:: Thirty adolescents were randomly assigned to the following groups: 1) 6.0% hydrogen peroxide (White Class with calcium - FGM); 2) 7.5% hydrogen peroxide (White Class with calcium - FGM); 3) 10% hydrogen peroxide (Oral B 3D White - Oral-B); 4) Control group - placebo. Assessments were performed prior to treatment as well as at 7, 30, 180 and 360 days after treatment. Friedman's ANOVA was used to analyze color. The Kruskal-Wallis test followed by Dunn's post hoc test was used to compare the groups at the different evaluation times. Answers on the questionnaires were ranked, and non-parametrical tests were employed. The groups were compared in each period using the Kruskal-Wallis test followed by the Student-Newman-Keuls test. Categorical data were analyzed using Fisher's exact test, and the Wilcoxon test was used for the analysis of different periods. P-values were corrected using the Hyan-Holm step-down Bonferroni procedure. Clinicaltrials.gov: NCT01998386. RESULTS:: Similar results were obtained one month after treatment with both tooth whitening gels and whitening strips. Patients were partially satisfied with the treatment after the first and second weeks and would recommend it. All products demonstrated color stability after 12 months of follow-up. CONCLUSIONS:: The bleaching procedure was efficient, and the patients could perceive its result. Further investigations are needed to determine the effects of bleaching on young teeth.


Subject(s)
Hydrogen Peroxide , Tooth Bleaching Agents , Tooth Bleaching/methods , Adolescent , Analysis of Variance , Calcium , Child , Color , Colorimetry , Dentin Sensitivity/chemically induced , Female , Follow-Up Studies , Humans , Male , Patient Satisfaction , Reproducibility of Results , Self Administration , Statistics, Nonparametric , Surveys and Questionnaires , Time Factors , Treatment Outcome , Young Adult
11.
Clinics ; 72(3): 161-170, Mar. 2017. tab, graf
Article in English | LILACS | ID: biblio-840054

ABSTRACT

OBJECTIVES: To evaluate the colorimetric change in incisors and canines of adolescents aged 12 to 20 years submitted to at-home whitening and to evaluate satisfaction, sensitivity and discomfort during the procedures through a questionnaire. METHOD: Thirty adolescents were randomly assigned to the following groups: 1) 6.0% hydrogen peroxide (White Class with calcium - FGM); 2) 7.5% hydrogen peroxide (White Class with calcium - FGM); 3) 10% hydrogen peroxide (Oral B 3D White - Oral-B); 4) Control group - placebo. Assessments were performed prior to treatment as well as at 7, 30, 180 and 360 days after treatment. Friedman’s ANOVA was used to analyze color. The Kruskal-Wallis test followed by Dunn’s post hoc test was used to compare the groups at the different evaluation times. Answers on the questionnaires were ranked, and non-parametrical tests were employed. The groups were compared in each period using the Kruskal-Wallis test followed by the Student-Newman-Keuls test. Categorical data were analyzed using Fisher's exact test, and the Wilcoxon test was used for the analysis of different periods. P-values were corrected using the Hyan-Holm step-down Bonferroni procedure. Clinicaltrials.gov: NCT01998386. RESULTS: Similar results were obtained one month after treatment with both tooth whitening gels and whitening strips. Patients were partially satisfied with the treatment after the first and second weeks and would recommend it. All products demonstrated color stability after 12 months of follow-up. CONCLUSIONS: The bleaching procedure was efficient, and the patients could perceive its result. Further investigations are needed to determine the effects of bleaching on young teeth.


Subject(s)
Humans , Male , Female , Child , Adolescent , Young Adult , Hydrogen Peroxide , Tooth Bleaching Agents , Tooth Bleaching/methods , Analysis of Variance , Calcium , Color , Colorimetry , Dentin Sensitivity/chemically induced , Follow-Up Studies , Patient Satisfaction , Reproducibility of Results , Self Administration , Statistics, Nonparametric , Surveys and Questionnaires , Time Factors , Treatment Outcome
12.
J Phys Ther Sci ; 29(12): 2107-2111, 2017 Dec.
Article in English | MEDLINE | ID: mdl-29643585

ABSTRACT

[Purpose] Problems involving the temporomandibular joint and associated structures can lead to temporomandibular disorder (TMD). The aim of the present study was to evaluate muscle activity in individuals with a diagnosis of TMD before and after treatment with low-level laser therapy (LLLT) through the use of electromyography (EMG). [Subjects and Methods] Male and female individuals aged 14 to 23 years were evaluated. TMD was determined by a clinical examination and the administration of the Research Diagnostic Criteria for Temporomandibular Disorders, followed by the evaluation of sensitivity to palpation of the masseter and anterior temporal muscles as well as the EMG determination of muscle activity. The participants were randomly allocated to an active LLLT group (n=9) and sham group (n=7). Twelve sessions of LLLT were conducted using a wavelength of 780 nm, energy density of 25 J/cm2, power of 50 mW, power density of 1.25 W/cm2 and a 20-second exposure time or sham LLLT. Muscle activity was determined prior to treatment and after the last session. [Results] During the isometric evaluation of the masseter and anterior temporal muscles, an increase in the mean EMG signal was found in the group submitted to active LLLT. When evaluated individually, some participants in the active LLLT group demonstrated a reduction in muscle activity, but no significant differences were found in the mean EMG signal between the initial and final evaluations. [Conclusion] Further studies with a larger sample size are needed to confirm the present findings.

13.
ARS med. (Santiago, En línea) ; 42(2): 34-41, 2017. Tab, ilus
Article in Spanish | LILACS | ID: biblio-1016581

ABSTRACT

Resumen: El aprendizaje de los estudiantes de Medicina de Pregrado en ambiente simulado constituye una alternativa en la obtención de competencias técnicas y no técnicas. Objetivo: Desarrollar un fantoma e implementar un taller modular de entrenamiento de paracentesis abdominal en ambiente simulado para estudiantes de Medicina. Métodos: Se diseñaron y desarrollaron modelos para la realización de paracentesis abdominal en la Escuela de Diseño de la Pontificia Universidad Católica de Chile (PUC) y se implementó un taller para alumnos de 4to año de Medicina de la PUC, utilizando un enfoque constructivista, sesiones de entrenamiento simulado con debriefing basadas en el modelo plus-delta y evaluación pre y post-procedimiento siguiendo los principios de evaluación para el aprendizaje. Resultados: Se desarrollaron 3 prototipos hasta llegar a un modelo definitivo de alta fidelidad basado en la percepción de 20 expertos. 237 alumnos asistieron a un taller de paracentesis abdominal en el Centro de Cirugía Experimental y Simulación Universidad Católica (UC). Este consistió en una actividad práctica grupal (7-8 alumnos por sesión) que incluyó: una evaluación pre-sesión, un vídeo instruccional, una demostración en tiempo real en el fantoma por parte de un docente, la realización guiada del procedimiento por parte de los alumnos, debriefing y cierre de la sesión. Conclusiones: Un modelo de enseñanza en ambiente simulado es posible de ser diseñado e implementado exitosamente en un centro educacional para estudiantes de Medicina de Pregrado. Este taller de paracentesis permite entrenar a los alumnos en la realización de paracentesis abdominal en un ambiente seguro para los alumnos y pacientes y puede ser implementado a bajo costo en otros centros o instituciones. (AU)


Abstract: Simulated environments are an option in the learning process of undergraduate medical students in order to obtain technical and non-technical. Aim: To develop a mannequin for abdominal paracentesis and the implementation of a training workshop to perform abdominal paracentesis in a simulated environment for undergraduate medical students. Methods: The prototypes were designed and developed to perform abdominal paracentesis at the School of Design at the Pontificia Universidad Católica de Chile (PUC) and a workshop was implemented in a course with 4-year medical students at the PUC, using a constructivist approach and simulated training sessions and providing debriefing (based on plus-delta model) and pre-post training assessment following the principles of Assessment for Learning. Results: Three prototypes were developed until the final high-fidelity-mannequin was achieved. The abdominal paracentesis workshop was attended by 237 students at the Universidad Católica (UC) Experimental Surgery and Simulation Center. This was a hands-on group activity (7-8 students per session) including pre-session assessment, instructional video-tape, real-time demonstration of abdominal paracentesis procedure by the clinical teacher, followed by abdominal paracentesis performed by the students, debriefing and closing session. Conclusions: A teaching model in a simulated environment is feasible to be successfully designed and implemented in an educational center for undergraduate medical students. This workshop allows students training process to perform abdominal paracentesis in a safe environment for students and patients and it can be implemented in other centers or institutions with low cost.(AU)


Subject(s)
Humans , Male , Female , Adaptive Clinical Trials as Topic , Students, Medical , Paracentesis , Education, Medical , Abdomen
14.
Case Rep Dent ; 2016: 9685429, 2016.
Article in English | MEDLINE | ID: mdl-27478655

ABSTRACT

Background. Melnick-Needles Syndrome is rare congenital hereditary skeletal dysplasia caused by mutations in the FLNA gene, which codifies the protein filamin A. This condition leads to serious skeletal abnormalities, including the stomatognathic region. Case Presentation. This paper describes the case of a 13-year-old girl diagnosed with Melnick-Needles Syndrome presenting with different forms of skeletal dysplasia, such as cranial hyperostosis, short upper limbs, bowed long bones, metaphyseal thickening, genu valgum (knock-knee), shortened distal phalanges, narrow pelvis and shoulders, rib tapering and irregularities, elongation of the vertebrae, kyphoscoliosis, micrognathia, hypoplastic coronoid processes of the mandible, left stylohyoid ligament suggesting ossification, and dental development anomalies. Conclusion. Knowledge of this rare syndrome on the part of dentists is important due to the fact that this condition involves severe abnormalities of the stomatognathic system that cause an impact on the development of the entire face as well as functional and esthetic impairments.

15.
Trials ; 16: 551, 2015 Dec 03.
Article in English | MEDLINE | ID: mdl-26635011

ABSTRACT

BACKGROUND: The elimination of pathogenic microorganisms from the root canal system is one of the major steps required for successful endodontic treatment. The aim of the proposed study is to conduct a randomized, controlled, clinical trial for the clinical and radiographic evaluation of the effectiveness of photodynamic therapy during the endodontic treatment of primary teeth. METHODS: Thirty primary anterior teeth in children aged 3 to 6 years old will be randomly divided into 2 groups: a control group, which will receive conventional treatment, and an experimental group, which will be subjected to photodynamic therapy. Microbiological evaluations will be performed before and after endodontic treatment. Moreover, clinical and radiographic evaluations will be performed on the day of treatment as well as 1, 3 and 6 months after treatment. Comparisons will be made of the two study groups. The data will be tabulated and presented in a descriptive, analytical fashion. Depending on the distribution (normal or non-normal), either the t test, ANOVA or the Mann-Whitney test will be used for analysis of the variables. The Wilcoxon test will be used for comparisons before and after treatment. P values<0.05 (95% significance level) will be considered indicative of statistically significant differences. DISCUSSION: As successful endodontic treatment is directly related to intra-canal bacterial disinfection and considering the difficult task of endodontic treatment in primary teeth, often due to difficulties in controlling young children, the internal anatomy of root canals and root resorption, the alternative of using PDT is a painless,easy-to-administer method that does not lead to microbial resistance and can assist in the achievement of successful endodontic treatment in primary teeth by eliminating the pain children can experience due to retreatment as well as premature tooth loss. TRIAL REGISTRATION: The protocol for this study was registered with Clinical Trials number NCT02485210 on 30 july 2015.


Subject(s)
Dental Care for Children/methods , Dental Pulp Cavity/drug effects , Methylene Blue/therapeutic use , Periapical Periodontitis/drug therapy , Photochemotherapy , Photosensitizing Agents/therapeutic use , Root Canal Therapy/methods , Tooth, Deciduous/drug effects , Analysis of Variance , Brazil , Child , Child, Preschool , Clinical Protocols , Dental Pulp Cavity/diagnostic imaging , Dental Pulp Cavity/microbiology , Female , Humans , Male , Methylene Blue/adverse effects , Periapical Periodontitis/diagnostic imaging , Periapical Periodontitis/microbiology , Photochemotherapy/adverse effects , Photosensitizing Agents/adverse effects , Radiography , Research Design , Root Canal Therapy/adverse effects , Statistics, Nonparametric , Time Factors , Tooth, Deciduous/diagnostic imaging , Tooth, Deciduous/microbiology , Treatment Outcome
16.
Psicol. teor. pesqui ; 31(3): 389-395, tab
Article in Portuguese | LILACS | ID: lil-764608

ABSTRACT

RESUMOO objetivo do estudo foi determinar a prevalência de sinais e sintomas de disfunção temporomandibular (DTM), segundo o nível de ansiedade de adolescentes da cidade de São Roque-SP. Foi utilizado o Índice de Fonseca para determinar a presença e o grau de severidade da DTM. Para avaliar o nível de ansiedade, foi utilizado o Inventário de Ansiedade Traço-Estado. Os participantes foram 3538 adolescentes entre 10 e 19 anos. Os resultados revelaram que 73,3% dos adolescentes apresentavam DTM e 72,7%, apresentavam ansiedade. Foram observadas associações estatisticamente significativas entre a presença de DTM e a presença de ansiedade, mas apenas com o sexo feminino, e correlação positiva, embora baixa, entre o grau de DTM e o nível de ansiedade. Conclui-se que adolescentes do sexo feminino apresentam maior chance de desenvolver DTM que os do sexo masculino, e quanto maior o nível de ansiedade do adolescente, maior a chance de desenvolver DTM.


ABSTRACTThe aim of this study was to determine the prevalence of signs and symptoms of temporomandibular disorder (TMD), according to the level of anxiety in adolescents in the city of São Roque-SP. The Fonseca Index was used to determine the presence and severity of TMD. To assess the level of anxiety the State-Trait Anxiety Inventory it was used. The participants were 3,538 adolescents with ages varying between 10 and 19 years. The results revealed that 73.3% of the adolescents had TMD, and that a "slight" degree of TMD was the most prevalent category. Anxiety was present in 72.7% of the adolescents. The analysis showed the existence of a significant association among female students between the presence of TMD and anxiety. A significant positive correlation was observed between the degree of TMD and the level of anxiety. The results indicate that female adolescents have a higher chance of developing TMD than male adolescents, and that the chance of developing TMD augments with the level of anxiety.

17.
Rev. CEFAC ; 17(1): 111-116, Jan-Feb/2015. tab
Article in Portuguese | LILACS | ID: lil-741946

ABSTRACT

OBJETIVO: avaliar se há relação entre bruxismo e presença de ruídos articulares em crianças. MÉTODOS: participaram do estudo 48 crianças entre 6 e 9 anos atendidas na Clínica Infantil da Faculdade de Odontologia da Universidade Nove de Julho. Foram selecionadas 21 crianças com bruxismo e 27 crianças no grupo controle. Um único examinador previamente treinado e "cego" em relação aos grupos realizou exame de palpação manual e auscultação bilateral das Articulações Temporomandibulares com a utilização de estetoscópio, extra-auricular lateral e dorsal para a análise dos ruídos articulares, diferenciando-os em crepitação e estalidos. Foi realizado o número mínimo de 3 repetições nas mensurações dos ruídos para cada criança. Foram realizadas as análises descritivas de todas as variáveis e o teste qui-quadrado foi utilizado para avaliar a associação entre as variáveis, adotando-se um nível de significância de 5%. RESULTADOS: em relação à presença de ruído 37,5% (n=18) apresentaram algum tipo de ruído articular, sendo que 72,2% (n=13) apresentaram estalido e 27,8% (n=5) apresentaram crepitação. Das 18 crianças que apresentaram algum tipo de ruído, 66,7% (n=12) também eram bruxistas. Foi observada associação estatisticamente significante entre a presença de ruído e bruxismo. Ao analisar a associação entre ruído e as variáveis gênero e idade, o grupo estudado não houve associação entre ruído e gênero, porém em relação à idade, houve uma maior porcentagem de crianças sem a presença de ruído articular aos 6 anos de idade, sendo estatisticamente significante. CONCLUSÃO: os dados do presente estudo mostraram associação entre bruxismo e ruídos articulares em crianças. .


PURPOSE: the aim of the present study was to determine whether bruxism is associated with joint sounds in children. METHODS: children aged six to nine years were recruited from the pediatric clinic of the School of Dentistry of University Nove de Julho (Brazil). Twenty-one children with bruxism and 27 children without this condition (control group) were selected. The evaluation was performed by a previously trained examiner who was blinded to the allocation of the groups and involved manual palpation as well as lateral and dorsal extra-auricular auscultation of the temporomandibular joints with the aid of a stethoscope for the determination of joint sounds, differentiating a click/pop from crepitus. At least three readings were performed on each child. Descriptive statistics were conducted and the chi-square test was used to test associations among the variables, with the level of significance set to 5% (p < 0.05). RESULTS: a total of 37.5% (n = 18) of the sample exhibited some type of joint sound. Among these children, 72.2% (n = 13) exhibited a click/pop and 27.8% (n = 5) exhibited crepitus. Among the 18 children with joint sounds, 66.7% (n = 12) also had bruxism. A statistically significant association was found between joint sounds and bruxism. No association was found between joints sounds and sex. However, a significant association was found with regard to age, as a greater percentage of children at six years of age had no joint sounds. CONCLUSION: the present findings demonstrate an association between bruxism and joint sounds in children. .

18.
J Oral Maxillofac Surg ; 73(4): 622-9, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25542604

ABSTRACT

PURPOSE: The aim of this pilot study was to evaluate the effect of low-level laser therapy on pain, mandibular movements, and occlusal contacts in adolescents and young adults with temporomandibular disorder. MATERIALS AND METHODS: Individuals aged 14 to 23 years were evaluated. The Research Diagnostic Criteria for Temporomandibular Disorders were used for the diagnosis of temporomandibular disorders. Pain was assessed with a visual analog scale. Occlusal contacts were recorded using the T-Scan III program (Tekscan, Boston, MA). The participants were randomly allocated to 2 groups: active or placebo laser treatment. The laser parameters were as follows: wavelength of 780 nm, energy density of 33.5 J/cm(2), power of 50 mW, power density of 1.67 W/cm(2), and 20-second exposure time. The Kolmogorov-Smirnov test was used to determine the normality of the data distribution. The paired t test was used for the comparisons of the pretreatment and post-treatment results. The SPSS program for Windows (version 15.0; SPSS, Chicago, IL) was used for all analyses, with the level of significance set at 5% (P < .05). RESULTS: No statistically significant differences between groups were found for the right and left anterior temporal muscles (P = .3801 and P = .5595, respectively), superior masseter muscles (P = .087 and P = .1969, respectively), medial masseter muscles (P = .2241 and P = .076, respectively), or inferior masseter muscles (P = .5589 and P = .3268, respectively) after treatment. CONCLUSIONS: No statistically significant differences were found regarding pain, mandibular range of motion, or the distribution of occlusal contacts after treatment with low-level laser therapy. These preliminary results need to be verified in a larger sample of patients to confirm the lack of response to low-level laser therapy.


Subject(s)
Low-Level Light Therapy/methods , Temporomandibular Joint Disorders/radiotherapy , Temporomandibular Joint Dysfunction Syndrome/radiotherapy , Adolescent , Dental Occlusion , Facial Pain/radiotherapy , Female , Follow-Up Studies , Humans , Male , Masseter Muscle/radiation effects , Muscle Fatigue/radiation effects , Myalgia/radiotherapy , Pain Measurement/methods , Placebos , Radiotherapy Dosage , Range of Motion, Articular/radiation effects , Single-Blind Method , Sound , Temporal Muscle/radiation effects , Visual Analog Scale , Young Adult
19.
Trials ; 15: 443, 2014 Nov 14.
Article in English | MEDLINE | ID: mdl-25394474

ABSTRACT

BACKGROUND: Halitosis is a common problem that affects a large portion of the population worldwide. The origin of this condition is oral in 90% and systemic in 10% of cases. The unpleasant odor is mainly the result of volatile sulfur compounds produced by Gram-negative bacteria. However, it has recently been found that anaerobic Gram-positive bacteria also produce hydrogen sulfide (H2S) in the presence of amino acids, such as cysteine. Light, both with and without the use of chemical agents, has been used to induce therapeutic and antimicrobial effects. In photodynamic therapy, the antimicrobial effect is confined to areas covered by photosensitizing dye. The aim of the present study is to evaluate the antimicrobial effect of photodynamic therapy on halitosis in adolescents through the analysis of volatile sulfur compounds measured using gas chromatography and microbiological analysis of coated tongue. METHODS/DESIGN: A quantitative clinical trial will be carried out involving 60 adolescents randomly divided into the following groups: group 1 will receive treatment with a tongue scraper, group 2 will receive photodynamic therapy applied to the posterior two-thirds of the dorsum of the tongue, and group 3 will receive combined treatment (tongue scraper and photodynamic therapy). Gas chromatography (OralChromaTM) and microbiological analysis will be used for the diagnosis of halitosis at the beginning of the study. Post-treatment evaluations will be conducted at one hour and 24 hours after treatment. The statistical analysis will include the Shapiro-Wilk test for the determination of the distribution of the data. If normal distribution is demonstrated, analysis of variance followed by Tukey's test will be used to compare groups. The Kruskal-Wallis test followed by the Student-Newman-Keuls test will be used for data with non-normal distribution. Either the paired t-test or the Wilcoxon test will be used to compare data before and after treatment, depending on the distribution of the data. DISCUSSION: The results of this trial will determine the efficacy of using photodynamic therapy alone or in combination with a tongue scraper to treat bad breath in adolescents. TRIAL REGISTRATION: The protocol for this study was registered with Clinical Trials (registration number NCT02007993) on 10 December 2013.


Subject(s)
Halitosis/drug therapy , Photochemotherapy , Research Design , Tongue/microbiology , Adolescent , Age Factors , Bacteria/growth & development , Bacteria/metabolism , Biofilms/growth & development , Brazil , Chromatography, Gas , Clinical Protocols , Combined Modality Therapy , Dental Devices, Home Care , Female , Halitosis/diagnosis , Halitosis/microbiology , Humans , Male , Methylene Blue/administration & dosage , Oral Hygiene/instrumentation , Photosensitizing Agents/administration & dosage , Sulfur Compounds/metabolism , Time Factors , Treatment Outcome , Volatilization
20.
Trials ; 15: 395, 2014 Oct 14.
Article in English | MEDLINE | ID: mdl-25315893

ABSTRACT

BACKGROUND: Technological innovations in dental materials have been fueled by the desire of patients to improve the esthetics of their teeth. This emphasis on esthetics has led dentists to seek resources that respect the standards established by society, but without compromising the integrity of the teeth. METHODS/DESIGN: The aim of the proposed controlled clinical trial will be to assess colorimetric changes and increased dental sensitivity in adolescent patients submitted to tooth whitening with 6% and 7.5% hydrogen peroxide using home kits with whitening strips. Adolescents aged 12 to 20 years will be allocated to different groups based on treatment (n = 16 per group): (1) placebo; (2) 6.0% hydrogen peroxide (White Class with Calcium, FGM); (3) 7.5% hydrogen peroxide (White Class with Calcium, FGM); and (4) 7.5% hydrogen peroxide (Oral B 3D White, Oral-B). After the whitening procedures, the participants will be evaluated using a visual analog scale for tooth sensitivity and digital spectrophotometry to measure changes in color. Descriptive analysis of the data will be performed. Either the chi-squared test or Fisher's exact test will be used for the determination of associations among the categorical variables. Student's t-test and analysis of variance will be used to compare mean colorimetric data. Pearson's correlation coefficients will be calculated to determine the strength of correlations among the continuous variables. DISCUSSION: This randomized trial will provide an opportunity to evaluate products such as whitening strips in comparison to other self-administered methods, especially in adolescents. TRIAL REGISTRATION: The protocol for this study was submitted to Clinical Trials in November 2013 with registration number NCT01998386.


Subject(s)
Hydrogen Peroxide/therapeutic use , Research Design , Tooth Bleaching Agents/therapeutic use , Tooth Bleaching/methods , Tooth Discoloration/therapy , Adolescent , Age Factors , Brazil , Chi-Square Distribution , Child , Clinical Protocols , Female , Gels , Humans , Hydrogen Peroxide/adverse effects , Male , Pain Measurement , Time Factors , Tooth Bleaching/adverse effects , Tooth Bleaching Agents/adverse effects , Tooth Discoloration/diagnosis , Toothache/chemically induced , Toothache/diagnosis , Treatment Outcome , Young Adult
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