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1.
Diagn Cytopathol ; 51(6): E181-E184, 2023 Jun.
Article in English | MEDLINE | ID: mdl-36880217

ABSTRACT

Myoepitheliomas are rare tumours of salivary glands. Mucinous myoepithelioma (MM) is a newly described variant with rare cases reported in the literature. This case report highlights cytopathologic features with histologic follow up of MM.


Subject(s)
Myoepithelioma , Parotid Neoplasms , Humans , Myoepithelioma/pathology , Biopsy, Fine-Needle , Parotid Neoplasms/pathology , Follow-Up Studies , Parotid Gland/pathology
2.
Int J Surg Pathol ; 25(7): 592-598, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28530163

ABSTRACT

Histoplasmosis is an invasive mycosis caused by inhalation of the spores of dimorphic fungi Histoplasma capsulatum. The disease manifests in the lung as acute or chronic pulmonary histoplasmosis and in severe cases gets disseminated in multiple organs like skin, adrenal gland, central nervous system, lymph node, liver, spleen, bone marrow, and gastrointestinal tract. It occurs most commonly in immunodeficient patients like HIV-positive patients and transplant recipients, while immunocompetent hosts are affected rarely. In cases of gastrointestinal histoplasmosis, the samples are collected for culture and biopsy should be sent for histopathological examination for definitive diagnosis. We conducted a retrospective study of colonic biopsies performed in the department of gastroenterology in a tertiary care hospital of north India from January 2014 to December 2015. Five cases of colonic histoplasmosis were diagnosed on histopathology out of which 4 patients were from north India while 1 patient was from Myanmar. The patients presented with various complaints, including loose stools, diarrhea, altered bowel habits, and gastrointestinal bleeding. The prognosis is very good after early and aggressive treatment while the disease is fatal if it remains untreated. In our study, 2 patients died within few days of diagnosis due to delay in the diagnosis, dissemination, and associated complications. Other patients were started on amphotericin B deoxycholate and are under follow-up. An early diagnosis of gastrointestinal histoplasmosis is important as appropriate treatment leads to long-term survival while untreated cases are almost fatal.


Subject(s)
Antifungal Agents/therapeutic use , Colon/pathology , Diarrhea/pathology , Gastrointestinal Hemorrhage/pathology , Histoplasmosis/pathology , Adult , Aged , Amphotericin B/therapeutic use , Biopsy , Colonoscopy , Deoxycholic Acid/therapeutic use , Diarrhea/drug therapy , Diarrhea/microbiology , Diarrhea/mortality , Drug Combinations , Female , Follow-Up Studies , Gastrointestinal Hemorrhage/drug therapy , Gastrointestinal Hemorrhage/microbiology , Gastrointestinal Hemorrhage/mortality , Histoplasma/isolation & purification , Histoplasmosis/drug therapy , Histoplasmosis/microbiology , Histoplasmosis/mortality , Humans , India , Male , Middle Aged , Prognosis , Retrospective Studies , Time Factors
4.
Indian J Radiol Imaging ; 26(3): 383-385, 2016.
Article in English | MEDLINE | ID: mdl-27857467

ABSTRACT

We report the eighth case of eosinophilic mastitis and the first one without an association with peripheral eosinophilia or systemic involvement. A 51-year-old diabetic presented with a painful right breast lump. The mammogram, ultrasound, and magnetic resonance imaging suggested a diagnosis of periductal mastitis, however, a sinister etiology of breast carcinoma could not be ruled out. Diagnosis was made by vacuum assisted biopsy which revealed features of eosinophilic mastitis.

6.
Southeast Asian J Trop Med Public Health ; 40(5): 1087-91, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19842393

ABSTRACT

Blood donors are deferred from donating blood for several reasons, either permanently or temporarily. Losses related to disease marker rates are well established. Donor and donation losses for other reasons, however, have not been extensively quantified. This study quantified the rate of and reasons for donor deferral among Delhi donors. A retrospective study was conducted by reviewing the deferral donor records from 1 January 2007 to 31 December 2008. The percentage of deferred donors was 9% with majority of them (91.0%) being deferred for temporary reasons. Anemia was the most frequent cause for donor rejection (32.8%). Permanent deferral accounted for 9.1% with hypertension being the most common cause (29.4%) in this category.


Subject(s)
Blood Banks/organization & administration , Blood Donors/statistics & numerical data , Adolescent , Adult , Blood Banks/statistics & numerical data , Female , Humans , India , Male , Middle Aged , Retrospective Studies , Young Adult
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