[Modulated kinesitherapy in rehabilitation of patients with cardiovascular diseases]. / Modulirovannaia kineziterapiia v reabilitatsii bol'nykh s zabolevaniiami serdechno-sosudistoi sistemy.

Modulated kinesitherapy (MK) is a new method based on synchronization of vegetative and motor components in walking at a pace corresponding to actual heart rate which is maintained during the procedure with cardiotrainer Marafon. MK produced the following therapeutic effects: optimization of cardiovascular functions (weakening of postload on the heart with lowering of arterial pressure; improvement of coronary blood flow, stabilization of the heart rate and cardiac pump function); marked antiarrhythmic effect, normalization of autonomic nervous system tonicity, neurohumoral and psychoemotional state. MK is indicated in ischemic heart disease, essential hypertension, cardiac arrhythmia, vegetovascular asthenia.

[Clinical efficacy of non-invasive evaluation of intra- and interatrial conduction in patients with ischemic heart disease]. / Klinicheskaia otsenka ispol'zovaniia neinvazivnogo metoda opredeleniia vnutri- i mezhpredserdnoi provodimosti u bol'nykh ishemicheskoi bolezn'iu serdtsa.

AIM: To try feasibility of non-invasive registration of intra- and interatrial conduction by means of simultaneous registration of echo-CG (in B and M modes) and ECG. MATERIALS AND METHODS: The time of intra- and interatrial conduction was measured at simultaneous registration of echo- CG (B and M modes) and ECG in standard lead II. The time of atrial conduction was registered in ms from the start of ECG wave "P" to beginning of echo-CG mechanical contractions. The results were compared to those obtained at the direct method (registration of atrial conduction by electrode fixed on the atrial myocardium). RESULTS: The data by the two above methods showed high correlation (for intraatrial conduction r = 0.93, for the interatrial one r = 0.85). The study confirmed the leading role of end-diastolic volume of the left ventricle and/or uneven wave movement along the atria in development of supraventricular arrhythmia in coronary heart disease. CONCLUSION: The proposed non-invasive method can find application for estimation of atrial conduction both in clinical practice and experiment. The time of exitation conduction through the atria measured by the new non-invasive method and the direct method is almost the same.

[The differentiated therapy of paroxysms of atrial fibrillation and flutter in patients with ischemic heart disease in relation to the duration of the arrhythmia before the start of treatment]. / Differentsirovannaia terapiia paroksizmov mertsaniia i trepetaniia predserdii u bol'nykh ishemicheskoi bolezn'iu serdtsa v zavisimosti ot prodolzhitel'nosti aritmii do nachala ee lecheniia.

AIM: To ascertain optimal antiarrhythmic therapy (AAT) in paroxysms of atrial fibrillation (AF) and atrial flutter (AFl) basing on their pretreatment duration. MATERIALS AND METHODS: A total of 2851 coronary heart disease (CHD) patients with AF and AFl paroxysms aged 40-75 years were treated from 1982 to 1996. The patients received sublingual or oral drugs (anaprilin, ethacizine, quinidine, etc.) or intravenous antiarrhythmic drugs (ritmilen, isoptin, novocainamide, etc). RESULTS: In pretreatment duration of AF and AFl up to 3 hours more pronounced effect was observed with sublingual and intravenous antiarrhythmic drugs. In the paroxysm duration up to 6 days, maximal antiarrhythmic effectiveness occurred in the use of intravenous antiarrhythmic drugs or quinidine, quinidine + verapamil. In the paroxysm duration from 7 days to several months, positive effect was achieved only in administration of quinidine or quinidine + verapamil. CONCLUSION: The principle of differentiated therapy of AF and AFl in CHD patients depending on the paroxysm duration before treatment allows choice of adequate therapy by enhancing its antiarrhythmic and weakening arrhythmogenic effects.

[Laser irradiation of venous blood for prevention of reperfusion syndrome in myocardial infarction]. / Primenenie lazernogo oblucheniia venoznoi krovi dlia preduprezhdeniia reperfuzionnogo sindroma pri infarkte miokarda.

The antioxidant effect encountered in laser irradiation of venous blood suggested the study of the possibility of its use for the prevention of the reperfusion syndrome in myocardial infarction (MI). Analysis of biochemical, electrophysiological, hemodynamic, and morphohistological data obtained in experiments on male rats and in clinical cases showed that irradiation of venous blood by the LG-75 helium-neon laser with a wavelength of 632.8 nm produced the best effect. The effect is realized through increase of collateral blood supply in the region of the MI and the antioxidant and antihypoxic action.