ABSTRACT
Common and usually self-limited diseases may occasionally have fatal consequences. Hydrocephalus is a very rare complication of mumps, with just a few cases reported in the literature. Here we report a fatal case of hydrocephalus presenting 19 years after mumps encephalitis. The long latency period between encephalitis and hydrocephalus-associated symptoms makes this case particularly interesting.
Subject(s)
Hydrocephalus/etiology , Meningoencephalitis/complications , Mumps/complications , Adult , Fatal Outcome , Humans , Hydrocephalus/virology , MaleABSTRACT
The pharmacological properties and anatomical distribution of alpha2-, beta1- and beta2-adrenoceptors in pigeon and chick brains were studied by both homogenate binding and tissue section autoradiography. [3H]Bromoxidine (alpha2-adrenoceptor-), [3H]CGP 12177 (beta-adrenoceptor) and [125I]cyanopindolol (beta-adrenoceptor) were used as radioligands. In both species, [3H]bromoxidine binding to avian brain tissue showed a pharmacological profile similar to that previously reported for alpha2-adrenoceptors in mammals. Regarding the anatomical distribution, the areas with the highest densities of alpha2-adrenoceptors in the pigeon brain included the hyperstriatum, nuclei septalis, tectum opticum and some brainstem nuclei. Most beta-adrenoceptors found in tissue membranes and sections from chick and pigeon brain were of the beta2 subtype, in contrast to what has been reported in the mammalian brain, where the beta1 subtype is predominant. A striking difference was found between the two species regarding the densities of these receptors: while pigeon brain was extremely rich in [125I]cyanopindolol binding throughout the brain (mainly cerebellum) in the pigeon, the levels of labelling in the chick brain were much lower; the exception was the cerebellum, which displayed a higher density than other parts of the brain in both species. Overall, our results support the proposed anatomical equivalences between a number of structures in the avian and mammalian encephalon.
Subject(s)
Brain/metabolism , Receptors, Adrenergic, alpha-2/metabolism , Receptors, Adrenergic, beta/metabolism , Adrenergic alpha-Agonists/pharmacology , Animals , Autoradiography , Brimonidine Tartrate , Chickens , Columbidae , Male , Quinoxalines/pharmacology , Receptors, Adrenergic, alpha-2/drug effects , Receptors, Adrenergic, beta/drug effects , Tissue DistributionABSTRACT
The death of a three-year-old child by asphyctic mechanism is described. The child was accidentally suspended by the neck from a half-opened car window. This report details the form in which the accident occurred. The influence of the type of window and the autopsy findings.
Subject(s)
Accidents, Home , Airway Obstruction/etiology , Asphyxia/etiology , Automobiles , Child, Preschool , Equipment Design , Humans , MaleABSTRACT
Se hace un estudio de los resultados obtenidos en 39 pacientes que presentaban pie varo equino congenito, en los cuales se utilizo la tecnica de Turco; de estos casos 10 lo presentaban en ambos pies, para un total de 58 pies operados. Los casos elegidos fueron de edades compreendidas entre los diez meses y los seis anos, aunque la mayoria se encontraba por debajo de los dos anos