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1.
Front Aging Neurosci ; 8: 85, 2016.
Article in English | MEDLINE | ID: mdl-27242507

ABSTRACT

The objective of our study was to evaluate the exercise and educational intervention in the city of Lubbock via GET FiT Lubbock (GFL) program. The GFL program was designed to increase exercise and educational opportunities, which positively impact health risk factors in Lubbock residents. The GFL program design included the recruitment of subjects to participate on a team that consisted of four individuals, each subject tracked their exercise minutes, and their educational session attendance. The tracking of exercise and educational sessions was done on the GFL website. Biometric testing was conducted pre- and post- intervention. The program was located within the Lubbock community in places that were close to their place of residence. The intervention included walking and educational sessions, including goal setting lectures, nutrition information, and exercise demonstrations. Study participants, included male and female adults who tracked their exercise time and educational sessions. Exercise minutes and educational session attendance were self-reported. Our data analysis revealed that significant difference was found between pre- and post- intervention measures, including weight, body mass index (BMI), high-density lipoprotein (HDL). Significant difference was found for weight, BMI, and HDL in females. Based on these findings, we conclude that the intervention showed positive effects on exercise and lifestyle.

2.
J Alzheimers Dis ; 48(2): 547-55, 2015.
Article in English | MEDLINE | ID: mdl-26402018

ABSTRACT

The Garrison Institute on Aging (GIA) is an established institute within Texas Tech University Health Sciences Center, whose mission is to promote healthy aging through cutting-edge research on Alzheimer's disease (AD) and other diseases of aging through innovative educational opportunities for students, clinicians, researchers, health care professionals, and the public. The GIA has multiple programs, including both research and education on healthy aging and AD, community outreach, caregiving, the Retired Senior Volunteer Program, Healthy Lubbock, the GIA Brain Bank, healthy aging seminars, research seminars, and collaborations and scholarships. The GIA programs connect basic and clinical researchers and health care professionals, and provide a unique environment to help our growing elderly population and patients with AD and their families.


Subject(s)
Academic Medical Centers , Alzheimer Disease/therapy , Health Services for the Aged , Alzheimer Disease/genetics , Alzheimer Disease/metabolism , Animals , Brain , Community-Institutional Relations , Geriatrics/education , Geriatrics/methods , Humans , Multiple Sclerosis/metabolism , Multiple Sclerosis/therapy , Patient Education as Topic , Texas , Tissue Banks , Volunteers
3.
Environ Geochem Health ; 37(3): 507-14, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25467206

ABSTRACT

Between 1564 and 1810, nearly 17,000 metric tons of mercury (Hg) vapor was released to the environment during cinnabar refining in the small town of Huancavelica, Peru. The present study characterizes individual exposure to mercury using total and speciated Hg from residential samples, total Hg in hair, and self-reported questionnaire data regarding factors influencing exposure (e.g., frequency of fish consumption, occupation). Total Hg concentrations in hair from 118 participants ranged from 0.10 to 3.6 µg/g, similar to concentrations found in the USA and lower than concentrations in other Hg-exposed populations around the world. Pearson's correlation coefficients for data in this study suggest that there is a positive correlation between concentrations of total Hg in hair and concentrations of total Hg in adobe bricks, dirt floors, and surface dust; however, these correlations are not statistically significant. Results of a one-way analysis of variance (ANOVA) identified that total Hg concentrations in hair were significantly related to gender (p < 0.001), living in a neighborhood where smelters were previously located (p = 0.021), smoking status (p = 0.003), frequency of house cleaning (p = 0.019), and frequency of fish consumption (p = 0.046). These results highlight the need for further studies to better characterize Hg exposure in Huancavelica, particularly as related to residential contamination. A comprehensive analysis of residential Hg contamination and exposure in Huancavelica will guide the development and implementation of mitigation and remediation strategies in the community to reduce potential health risks from residential Hg exposure.


Subject(s)
Environmental Exposure/analysis , Environmental Pollutants/analysis , Hair/chemistry , Mercury/analysis , Adult , Animals , Construction Materials/analysis , Dust/analysis , Environmental Monitoring , Female , Fishes , Floors and Floorcoverings , Food Contamination/analysis , Housing , Humans , Male , Mercury Compounds , Metallurgy , Peru , Sex Factors , Smoking
4.
Environ Geochem Health ; 37(2): 263-72, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25169738

ABSTRACT

Huancavelica, Peru, a historic cinnabar refining site, is one of the most mercury (Hg)-contaminated urban areas in the world. Exposure is amplified because residents build their adobe brick homes from contaminated soil. The objectives of this study were to compare two Hg-leaching procedures, and their application as risk-assessment screening tools in Hg-contaminated adobe brick homes in Huancavelica. The purpose was to evaluate potential health implications, particularly for children, after ingestion of Hg-contaminated particles. Hg was measured in adobe brick and dirt floor samples from 60 households by total Hg extraction, simulated gastric fluid (GF) extraction, and sequential selective extraction (SSE), which provides more detailed data but is resource-intensive. Most of the Hg present in samples was relatively insoluble, although in some households soluble Hg species were present at concentrations that may be of concern after ingestion. A strong correlation was identified between results from simulated GF extraction of adobe bricks and dirt floors and the more soluble fractions of Hg from SSE. Simulated GF extraction data were combined with ingestion and body mass characteristics for small children to compare potential risk of ingestion of Hg-contaminated soil with current health standards. Simulated GF extraction can be used as a risk assessment screening tool for effective allocation of time and resources to households that have measurable concentrations of bioaccessible Hg. Combining simulated GF extraction data with health standards enables intervention strategies targeted at households with the greatest potential health threat from ingestion of Hg-contaminated particles.


Subject(s)
Construction Materials/analysis , Environmental Pollutants/analysis , Mercury/analysis , Soil Pollutants/analysis , Biological Availability , Child , Cities , Environmental Exposure/analysis , Environmental Monitoring , Environmental Pollutants/chemistry , Floors and Floorcoverings , Housing , Humans , Mercury/chemistry , Peru , Soil Pollutants/pharmacokinetics
5.
PLoS One ; 8(9): e75179, 2013.
Article in English | MEDLINE | ID: mdl-24040399

ABSTRACT

This is the first study of adobe brick contamination anywhere in the world. Huancavelica, Peru is the site of historic cinnabar refining and one of the most mercury (Hg) contaminated urban areas in the world. Over 80% of homes in Huancavelica are constructed with adobe bricks made from Hg contaminated soil. In this study we measured total Hg concentrations in adobe brick, dirt floor, surface dust, and air samples from the interior of 60 adobe brick houses located in four neighborhoods. Concentrations of total Hg in adobe bricks, dirt floors, and surface dust ranged from 8.00 to 1070 µg/g, 3.06 to 926 µg/g, and 0.02 to 9.69 µg/wipe, respectively, with statistically significant differences between the four neighborhoods. Concentrations of Hg in adobe brick and dirt floor samples in Huancavelica were orders of magnitude higher than in Ayacucho, a non-mining town in Peru. A strong correlation exists between total Hg concentrations in adobe bricks and dirt floors which confirms that adobe bricks were being made on-site and not purchased from an off-site source. A strong correlation between surface dust and adobe bricks and dirt floors indicates that walls and floors serve as indoor sources of Hg contamination. Elemental Hg vapor concentrations were below detection (<0.5 µg/m(3)) in most homes; however in homes with detectable levels, concentrations up to 5.1 µg/m(3) were observed. No statistically significant differences in Hg vapor measurements were observed between neighborhoods. This study demonstrates that building materials used widely in developing communities, such as adobe bricks, may be a substantial source of residential Hg exposure in silver or gold refining communities where Hg is produced or used for amalgamation in artisanal gold production.


Subject(s)
Construction Materials/analysis , Environmental Monitoring , Environmental Pollutants/analysis , Housing , Mercury/analysis , Air/analysis , Cities/statistics & numerical data , Dust/analysis , Environmental Exposure/analysis , Environmental Pollutants/chemistry , Environmental Restoration and Remediation , Floors and Floorcoverings , Humans , Mercury/chemistry , Peru , Volatilization
6.
Sci Total Environ ; 426: 146-54, 2012 Jun 01.
Article in English | MEDLINE | ID: mdl-22542225

ABSTRACT

Detailed Spanish records of cinnabar mining and mercury production during the colonial period in Huancavelica, Peru were examined to estimate historical health risks to the community from exposure to elemental mercury (Hg) vapor resulting from cinnabar refining operations. Between 1564 and 1810, nearly 17,000 metric tons of Hg were released to the atmosphere in Huancavelica from Hg production. AERMOD was used with estimated emissions and source characteristics to approximate historic atmospheric concentrations of mercury vapor. Modeled 1-hour and long-term concentrations were compared with present-day inhalation reference values for elemental Hg. Estimated 1-hour maximum concentrations for the entire community exceeded present-day occupational inhalation reference values, while some areas closest to the smelters exceeded present-day emergency response guideline levels. Estimated long-term maximum concentrations for the entire community exceeded the EPA Reference Concentration (RfC) by a factor of 30 to 100, with areas closest to the smelters exceeding the RfC by a factor of 300 to 1000. Based on the estimated historical concentrations of Hg vapor in the community, the study also measured the extent of present-day contamination throughout the community through soil sampling and analysis. Total Hg in soils sampled from 20 locations ranged from 1.75 to 698 mg/kg and three adobe brick samples ranging from 47.4 to 284 mg/kg, consistent with other sites of mercury mining and use. The results of the soil sampling indicate that the present-day population of Huancavelica is exposed to levels of mercury from legacy contamination which is currently among the highest worldwide, consequently placing them at potential risk of adverse health outcomes.


Subject(s)
Air Pollution/statistics & numerical data , Environmental Monitoring/methods , Mercury/analysis , Soil Pollutants/analysis , Soil/chemistry , Air Pollutants/analysis , Mining , Peru
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