ABSTRACT
An ovarian enlargement (diameter, 8 cm) was identified and surgically excised from a 5-year-old female dog. Microscopic examination of the multinodular neoplasm revealed sheets of polygonal neoplastic cells with large nuclei, frequent mitosis, necrosis and haemorrhage. Immunohistochemically, the neoplastic cells were positive for vimentin and alkaline phosphatase but were negative for CD3, CD79a, cytokeratin, alpha-fetoprotein, inhibin-alpha and S-100. The histopathological diagnosis of the mass was unilateral ovarian dysgerminoma.
Subject(s)
Dog Diseases/diagnosis , Dysgerminoma/veterinary , Immunohistochemistry/veterinary , Ovarian Neoplasms/veterinary , Alkaline Phosphatase/analysis , Animals , Dog Diseases/pathology , Dog Diseases/surgery , Dogs , Dysgerminoma/diagnosis , Dysgerminoma/surgery , Female , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/surgery , Vimentin/analysisABSTRACT
Five new crown ether carboxyhc acid resins have been prepared by condensation polymerization of sym-(R)dibenzo-16-crown-5-oxyacetic acids with formaldehyde. Competitive alkali-metal cation sorption by these novel resins, which contain both ion-exchange and crown ether binding sites for metal ions, has been investigated. As the R-group was varied (methyl, ethyl, propyl, butyl, hexyl and decyl) both the alkali-metal cation sorption selectivity and efficiency were affected. The highest efficiency (loading) and Na(+) sorption selectivity were obtained when R = methyl, ethyl and propyl. The longer alkyl groups were found to be detrimental to both sorption efficiency and selectivity.