ABSTRACT
In vitro tests have shown that a treatment of blood according to the principle of hemofiltration is suitable both for the normalisation of excessive norepinephrine plasma level, e.g. following severe burns, and also for the elimination of toxic quantities of barbiturate and bromide resulting from poisoning by sedatives.
Subject(s)
Barbiturates/blood , Bromides/blood , Filtration , Norepinephrine/blood , Humans , In Vitro Techniques , MethodsABSTRACT
With the modified Astrup-plate method a spontaneous peripheral proteolysis was often found in chronical infections of the skin and mucous membranes. The origin of this proteolysis and its effects on the bacterial growth and wound healing were discussed.
Subject(s)
Bacterial Infections/enzymology , Endopeptidases/metabolism , Escherichia coli/enzymology , Escherichia coli/growth & development , Fibrinolysis , Leukocytes/enzymology , Leukocytes/metabolism , Trypsin/pharmacology , Trypsin Inhibitors/pharmacology , Wound HealingABSTRACT
With a modificated Astrup-fibrin plate-method also an inhibition of proteolysis can be registrated. In various medical areas a spontaneous peripheral proteolysis had been found, especially so in chronical bacterial infections.
Subject(s)
Bacterial Infections/enzymology , Endopeptidases/metabolism , Fibrinolysis , Autolysis/enzymology , Bacteriological Techniques , Chronic Disease , Escherichia coli Infections/enzymology , Fibrinolysin , Humans , Leukocytes/enzymology , Pharyngeal Diseases/enzymology , Postoperative Complications , Proteus Infections/enzymology , Pseudomonas Infections/enzymology , Sinusitis/enzymology , Skin Ulcer/enzymology , Staphylococcal Infections/enzymology , Trypsin InhibitorsABSTRACT
With a modification of the Astrup - fibrin - plate method about 300 patients were investigated. In chronic infections of the skin and mucous membranes a spontaneous peripheral proteolysis was found. There is a connection between infections, proteolysis and chronic continuance.