1.
Nat Prod Res
; 32(19): 2370-2374, 2018 Oct.
Article
in English
| MEDLINE
| ID: mdl-29252003
ABSTRACT
Stachartone A (1), a novel phenylspirodrimane dimer, was isolated from cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Its structure was elucidated by means of spectroscopic methods. At the same time, compound (1) was tested for its cytotoxicity against five human cancer cell lines.
Subject(s)
Sesquiterpenes/isolation & purification , Stachybotrys/chemistry , Antineoplastic Agents/chemistry , Antineoplastic Agents/isolation & purification , Antineoplastic Agents/pharmacology , Cell Line , Cell Line, Tumor , Dimerization , Humans , Mining , Molecular Structure , Polycyclic Sesquiterpenes , Sesquiterpenes/chemistry , Spiro Compounds/chemistry , Spiro Compounds/isolation & purification
2.
Fitoterapia
; 125: 94-97, 2018 Mar.
Article
in English
| MEDLINE
| ID: mdl-29288026
ABSTRACT
A new phenylspirodrimane dimer, named stachartarin A (1), was isolated from cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Its structures were elucidated by means of spectroscopic methods. At the same time, the compound was tested for its cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells.