Photodynamic therapy with BF-200 ALA gel for the treatment of actinic keratosis, Bowen´s disease and basal cell carcinoma in long term immunosuppressed patients after organ transplantation.

Continuous immunosuppression after organ transplantation is associated with an increased risk of developing keratinocyte neoplastic lesions. Topical photodynamic therapy represents a therapeutic approach for different keratinocyte neoplastic lesions. However, the specific efficacy and safety of this treatment in this immunocompromised population remains largely unknown. In this case report series, we show the efficacy and safety of photodynamic therapy with BF-200 ALA gel using red-light and daylight in immunocompromised patients. Out of 8 patients presented here, 1 was treated for 8 basal cell carcinomas, 1 for 2 Bowen´s disease lesions and 6 were treated for field cancerization including 4 to 10 actinic keratoses. Treatment response rates were above 75 %. The adverse events, including pain, did not differ from those already described for PDT. These data suggest that PDT with BF-200 ALA gel could be an effective and safe option to add to the treatment portfolio for neoplastic keratinocyte lesions in this high-risk population.

Quality of life in children with skin disease: A Spanish sample.

INTRODUCTION: The impact of skin diseases on quality of life varies widely, and some can have an impact similar to that of asthma or cystic fibrosis. MATERIAL AND METHODS: We conducted a cross-sectional, observational and descriptive study with the aim of describing the degree to which quality of life was affected in paediatric patients managed in a dermatology clinic by means of the Children's Dermatology Life Quality Index (CDLQI). RESULTS: In our study, the skin disease with the greatest impact on quality of life was atopic dermatitis, chiefly on account of symptoms like pruritus and insomnia. It was followed by acne, mainly due to the associated negative feelings (shame, sadness, etc.). Quality of life in patients with viral warts and molluscum contagiosum was mostly affected by the treatment, chiefly based on cryotherapy. Most patients with nevi or café-au-lait spots did not have a decreased quality of life, although up to one third of them had negative feelings in relation to their skin disease. DISCUSSION: Atopic dermatitis was the common skin disease that caused the greatest impairment in quality of life in our sample, although other diseases also had an impact on different dimensions of quality of life. We ought to underscore the recommendation to use less painful treatments than cryotherapy for viral warts and molluscum contagiosum, as the impairment in quality of life in paediatric patients with these conditions was mainly due to the treatment.

Estudio de la calidad de vida en Dermatología Pediátrica: un ejemplo de la población española / Quality of life in children with skin disease: A Spanish sample

Introducción: Las enfermedades cutáneas pueden afectar a la calidad de vida de forma muy variable; el impacto de algunas dermatosis puede ser similar al del asma o la fibrosis quística. Material y métodos: Realizamos un estudio observacional, descriptivo y transversal con el objetivo de describir el grado de afectación de la calidad de vida de los niños que acudieron a la consulta monográfica de Dermatología Pediátrica, mediante el Children's Dermatology Life Quality Index (CDLQI). Resultados: En este estudio la dermatosis con mayor impacto en la calidad de vida fue la dermatitis atópica, debido principalmente a síntomas como el prurito y el insomnio. El segundo grupo diagnóstico con mayor afectación fue el acné, debido principalmente a los sentimientos negativos (vergüenza, tristeza, etc.) asociados al mismo. Los pacientes con verrugas víricas y moluscos contagiosos tuvieron impacto en la calidad de vida debido principalmente al tratamiento de los mismos, que se realizó principalmente con crioterapia. La mayor parte de los pacientes con nevus o manchas café con leche no tuvieron afectación en la calidad de vida, si bien hasta un tercio de ellos tuvieron sentimientos negativos secundarios a su dermatosis. Discusión: La dermatitis atópica fue la enfermedad dermatológica común que más impactó en la calidad de vida en nuestra muestra de pacientes, aunque otros procesos también afectaron a la calidad de vida en distintos aspectos de la misma. Cabe destacar la recomendación de emplear en verrugas víricas y moluscos contagiosos tratamientos más indoloros que la crioterapia, ya que es el tratamiento lo que más impacta en la calidad de vida de los pacientes pediátricos. (AU)

Introduction: The impact of skin diseases on quality of life varies widely, and some can have an impact similar to that of asthma or cystic fibrosis. Material and methods: We conducted a cross-sectional, observational and descriptive study with the aim of describing the degree to which quality of life was affected in paediatric patients managed in a dermatology clinic by means of the Children's Dermatology Life Quality Index (CDLQI). Results: In our study, the skin disease with the greatest impact on quality of life was atopic dermatitis, chiefly on account of symptoms like pruritus and insomnia. It was followed by acne, mainly due to the associated negative feelings (shame, sadness, etc.). Quality of life in patients with viral warts and molluscum contagiosum was mostly affected by the treatment, chiefly based on cryotherapy. Most patients with nevi or café-au-lait spots did not have a decreased quality of life, although up to one third of them had negative feelings in relation to their skin disease. Discussion: Atopic dermatitis was the common skin disease that caused the greatest impairment in quality of life in our sample, although other diseases also had an impact on different dimensions of quality of life. We ought to underscore the recommendation to use less painful treatments than cryotherapy for viral warts and molluscum contagiosum, as the impairment in quality of life in paediatric patients with these conditions was mainly due to the treatment. (AU)

Revisión sistemática de estudios sobre intervenciones que promueven la salud en conductores profesionales

Resumen: Introducción: Los trabajadores que se dedican al rubro de conducción están expuestos a factores que dificultan su quehacer laboral, tales como: problemas asociados a la temperatura, ruidos y vibraciones, ventilación insuficiente e ineficiente, atascos y relacionamientos interpersonales con los pasajeros. Objetivo: Identificar, en el estado del arte disponible, qué intervenciones promueven la salud de los conductores profesionales. Material y método: Revisión sistemática, siguiendo las recomendaciones de Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA), orientada por la pregunta: ¿qué intervenciones promueven la salud de los conductores profesionales? Resultados: La búsqueda arrojó 1303 artículos, de los cuales se incluyeron 11; las intervenciones identificadas se asociaron a dispositivos portátiles y mensajería de salud móvil, entrevistas motivacionales, documentos interactivos, exposición a entornos naturales, programas intensivos, asesoramiento, cambios a nivel de políticas, cambios ambientales y de sistemas. Conclusión: Se identificaron intervenciones que incluyeron a la tecnología, entrevistas, el ambiente y control estratégico. Se recomienda la implementación de las intervenciones identificadas, pues se torna perentorio el abordaje de la salud de los conductores profesionales, considerando las características descritas en el presente estudio.

Resumo: Introdução: Os trabalhadores envolvidos na condução estão expostos a fatores que dificultam o seu trabalho, tais como: problemas associados à temperatura, ruído e vibrações, ventilação insuficiente e ineficiente, engarrafamentos e relações interpessoais com os passageiros. Objetivo: Identificar, a partir do estado da arte disponível, quais as intervenções que promovem a saúde dos condutores profissionais. Método: Revisão sistemática, seguindo as recomendações dos itens Preferred Reporting Items for Systematic Reviews e Meta-Analyses (PRISMA), orientada pela pergunta: Quais intervenções promovem a saúde dos condutores profissionais? Resultados: A pesquisa produziu 1303 artigos, dos quais 11 foram incluídos; as intervenções identificadas foram associadas a dispositivos portáteis e mensagens de saúde móveis, entrevistas motivacionais, documentos interativos, exposição a ambientes naturais, programas intensivos, aconselhamento, mudanças a nível político, mudanças ambientais e de sistemas. Conclusão: Foram identificadas intervenções que incluíram tecnologia, entrevistas, ambiente e controle estratégico; recomenda-se a implementação das intervenções identificadas, pois é imperativo abordar a saúde dos condutores profissionais, considerando as características descritas no presente estudo.

Abstract: Introduction: Workers engaged in the driving field are exposed to factors that hinder their work tasks, such as: problems associated with temperature, noise and vibrations, insufficient and inefficient ventilation, traffic jams and interpersonal relationships with passengers. Objective: To identify, in the available state of the art, which interventions promote the health of professional drivers. Method: Systematic review, following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), guided by the question: what interventions promote the health of professional drivers? Results: The search yielded 1303 articles, of which 11 were included; the interventions identified were associated with handheld devices and mobile health messaging, motivational interviewing, interactive documents, exposure to natural environments, intensive programs, counseling, policy-level changes, environmental and systems changes. Conclusion: Interventions were identified that included technology, interviews, the environment and strategic control; the implementation of the identified interventions is recommended, since it is urgent to address the health of professional drivers, considering the characteristics described in this study.

Not a matter of shape: The influence of tool characteristics on electrodermal activity in response to haptic exploration of Lower Palaeolithic tools.

OBJECTIVES: Haptics involves somatosensory perception through the skin surface and dynamic touch based on the proprioceptive response of the whole body. Handling Palaeolithic stone tools influences the arousal and attentional engagement, which can be detected and measured through electrodermal activity. Although tool shape has generally been studied to consider tool functions or tool making, it is also a major factor in tool sensing and haptic perception. The purpose of this survey is to analyze whether the electrodermal reactions are influenced by stone tool morphology. METHODS: We first quantify the morphological variability of 72 stone tools through geometric morphometrics. Then, 12 stone tools from the previous sample were randomly selected to perform the electrodermal analysis in a sample of 46 right-handed adults. RESULTS: Elongation is the main factor involved in Lower Palaeolithic shape variation, followed by the position of the maximum thickness. Attention and manipulation time are mainly influenced by tool size, while arousal mostly correlates with tool weight. Electrodermal activity is apparently not influenced by the overall tool shape. Tool size, weight, and base morphology are the variables that mainly trigger an electrodermal reaction. CONCLUSIONS: Electrophysiological reaction is more sensitive to specific physical features of the tool than to its general outline. These features are not particularly different in worked pebbles and handaxes in terms of grasping, but underwent remarkable changes in other technological traditions. That changes associated with behavioral performances can be employed in cognitive archaeology to investigate the relationships between tool sensing and tool use.

The European Biological Variation Study (EuBIVAS): a summary report.

Biological variation (BV) data have many important applications in laboratory medicine. Concerns about quality of published BV data led the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) 1st Strategic Conference to indicate need for new studies to generate BV estimates of required quality. In response, the EFLM Working Group on BV delivered the multicenter European Biological Variation Study (EuBIVAS). This review summarises the EuBIVAS and its outcomes. Serum/plasma samples were taken from 91 ostensibly healthy individuals for 10 consecutive weeks at 6 European centres. Analysis was performed by Siemens ADVIA 2400 (clinical chemistry), Cobas Roche 8000, c702 and e801 (proteins and tumor markers/hormones respectively), ACL Top 750 (coagulation parameters), and IDS iSYS or DiaSorin Liaison (bone biomarkers). A strict preanalytical and analytical protocol was applied. To determine BV estimates with 95% CI, CV-ANOVA after analysis of outliers, homogeneity and trend analysis or a Bayesian model was applied. EuBIVAS has so far delivered BV estimates for 80 different measurands. Estimates for 10 measurands (non-HDL cholesterol, S100-ß protein, neuron-specific enolase, soluble transferrin receptor, intact fibroblast growth-factor-23, uncarboxylated-unphosphorylated matrix-Gla protein, human epididymis protein-4, free, conjugated and %free prostate-specific antigen), prior to EuBIVAS, have not been available. BV data for creatinine and troponin I were obtained using two analytical methods in each case. The EuBIVAS has delivered high-quality BV data for a wide range of measurands. The BV estimates are for many measurands lower than those previously reported, having an impact on the derived analytical performance specifications and reference change values.

Within- and between-subject biological variation data for tumor markers based on the European Biological Variation Study.

OBJECTIVES: Reliable biological variation (BV) data are required for the clinical use of tumor markers in the diagnosis and monitoring of treatment effects in cancer. The European Biological Variation Study (EuBIVAS) was established by the EFLM Biological Variation Working Group to deliver BV data for clinically important measurands. In this study, EuBIVAS-based BV estimates are provided for cancer antigen (CA) 125, CA 15-3, CA 19-9, carcinoembryonic antigen, cytokeratin-19 fragment, alpha-fetoprotein and human epididymis protein 4. METHODS: Subjects from five European countries were enrolled in the study, and weekly samples were collected from 91 healthy individuals (53 females and 38 males; 21-69 years old) for 10 consecutive weeks. All samples were analyzed in duplicate within a single run. After excluding outliers and homogeneity analysis, the BVs of tumor markers were determined by CV-ANOVA on trend-corrected data, when relevant (Røraas method). RESULTS: Marked individuality was found for all tumor markers. CYFRA 21-1 was the measurand with the highest index of individuality (II) at 0.67, whereas CA 19-9 had the lowest II at 0.07. The CV I s of HE4, CYFRA 21-1, CA 19-9, CA 125 and CA 15-3 of pre- and postmenopausal females were significantly different from each other. CONCLUSIONS: This study provides updated BV estimates for several tumor markers, and the findings indicate that marked individuality is characteristic. The use of reference change values should be considered when monitoring treatment of patients by means of tumor markers.

The European Biological Variation Study (EuBIVAS): Biological Variation Data for Coagulation Markers Estimated by a Bayesian Model.

BACKGROUND: For biological variation (BV) data to be safely used, data must be reliable and relevant to the population in which they are applied. We used samples from the European Biological Variation Study (EuBIVAS) to determine BV of coagulation markers by a Bayesian model robust to extreme observations and used the derived within-participant BV estimates [CVP(i)] to assess the applicability of the BV estimates in clinical practice. METHOD: Plasma samples were drawn from 92 healthy individuals for 10 consecutive weeks at 6 European laboratories and analyzed in duplicate for activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen, D-dimer, antithrombin (AT), protein C, protein S free, and factor VIII (FVIII). A Bayesian model with Student t likelihoods for samples and replicates was applied to derive CVP(i) and predicted BV estimates with 95% credibility intervals. RESULTS: For all markers except D-dimer, CVP(i) were homogeneously distributed in the overall study population or in subgroups. Mean within-subject estimates (CVI) were <5% for APTT, PT, AT, and protein S free, <10% for protein C and FVIII, and <12% for fibrinogen. For APTT, protein C, and protein S free, estimates were significantly lower in men than in women ≤50 years. CONCLUSION: For most coagulation markers, a common CVI estimate for men and women is applicable, whereas for APTT, protein C, and protein S free, sex-specific reference change values should be applied. The use of a Bayesian model to deliver individual CVP(i) allows for improved interpretation and application of the data.

Características sociodemográficas, condiciones de trabajo y de salud de los conductores de autobuses chilenos / Sociodemographic characteristics, working and health conditions of Chilean bus drivers

OBJETIVO: Describir las características sociodemográficas, las condiciones de trabajo y de salud de los conductores de autobuses chilenos. MÉTODO: diseño descriptivo transversal. La población de estudio fueron los conductores de autobuses de la ciudad de Chile. Se llevó a cabo un muestreo probabilístico por conglomerado. Se necesitaba una muestra de 144 sujetos. La aplicación del cuestionario se realizó durante la jornada laboral. Se recogieron variables sociodemográficas, condiciones laborales y de salud de los conductores. Se realizó análisis descriptivo. RESULTADOS: 100% fue hombre. La edad media (DE) fue de 41 años (12,09). Prevalecen los sujetos con 9-12 años de estudios (nivel medio) (73,6%, n= 106). La mayoría cuenta con un contrato laboral de carácter indefinido (66,7%, n= 96). El 90,3% (n= 130) no supera los 828 dólares (660 mil pesos chilenos) de ingresos mensuales. El 51,4% (n= 74) cuenta con una experiencia laboral de 21 años o superior. El 20,8% (n= 30) presenta hipertensión arterial y el 17,4% (n= 25) diabetes. El 59,7% (n= 86) se caracterizó por tener sobrepeso u obesidad. El 81,9% (n= 118) tiene una vida sedentaria. El 41% (n= 59) reconoce fumar a diario, el 62,5 (n= 90) consume alcohol. Prevalecen las condiciones laborales negativas: horas de trabajo extras (75%, n= 108), ruidos elevados (72,9%, n= 105), agresión verbal (61,8%, n= 89) y agresión física (53,5%, n= 77). El 85,4% (n= 123) informa que nunca o casi nunca ha recibido cursos de formación para mejorar su actividad laboral (capacitación). CONCLUSIONES: las características sociodemográficas de los conductores, así como sus condiciones de salud y laborales les sitúa en una población de riesgo ante determinadas enfermedades cardiovasculares, así como ante posibles accidentes de tráfico

OBJECTIVE: to describe the sociodemographic characteristics, work and health conditions of Chilean bus drivers. METHOD: a cross-sectional descriptive design. The study population were the bus drivers from the city of Chile. Cluster probability sampling was conducted. A 144-subject sample was required. The questionnaire was applied during working hours, and collected sociodemographic variables, as well as working and health conditions of the drivers. Descriptive analysis was used. RESULTS: 100% were male, with a mean age (SD) of 41 years (12.09). There was a prevalence of subjects with 9-12 years of education (middle level) (73.6%, n= 106). The majority had indefinite employment contracts (66.7%, n= 96), and 90.3% (n= 130) had a monthly income below 828 dollars (660 thousand Chilean pesos). 51,4% (n= 74) had ≥ 21-year work experience. 20.8% (n= 30) presented hypertension and 81.9% (n= 118) led a sedentary life. 41% (n= 59) admitted smoking every day, and 62.5 (n= 90) drank alcohol. Negative working conditions prevailed: extra working hours (75%, n= 108), high level of noise (72.9%, n= 105), verbal abuse (61.8%, n= 89) and physical assault (53.5%, n= 77). 85.4% (n= 123) of the sample reported that they had never or seldom received training courses in order to improve their work activity (qualification). CONCLUSIONS: the sociodemographic characteristics of drivers, as well as their health and working conditions, place them as high-risk population for certain cardiovascular diseases, as well as for potential traffic accidents

European Biological Variation Study (EuBIVAS): within- and between-subject biological variation estimates for serum biointact parathyroid hormone based on weekly samplings from 91 healthy participants.

BACKGROUND: The European Biological Variation Study (EuBIVAS) was created by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group on Biological Variation to establish high-quality biological variation (BV) estimates for clinically important measurands. In this study, the aim was to deliver reliable BV estimates for the biointact parathyroid hormone (PTH 1-84). METHODS: Serum samples were obtained from a population of 91 healthy individuals (38 men, 43 pre-menopausal women, and 10 post-menopausal women; 21-69 years) from 5 European countries, with all samples stored at -80 °C prior to analysis. PTH 1-84 analysis was performed at the San Raffaele Hospital (Milan, Italy) on the Roche Cobas e801. All samples from each individual were analysed in duplicate within a single run. CV-ANOVA was applied, after analysis of variance homogeneity and outliers, to obtain BV estimates for PTH 1-84 with 95% CIs. RESULTS: The within-subject BV [CVI (95% CI)] estimates were significantly different between men and women [13.0% (12.1-14.2%) and 15.2% (14.3-16.3%), respectively], while the between-subject estimates [CVG (95% CI)] were similar (men: 26.8% (21.4-35.1%), pre-menopausal women: 27.8% (22.7-36.1%)], allowing for delivery of updated analytical performance specifications and reference change values. CONCLUSIONS: Updated BV estimates for serum PTH 1-84 based on the large-scale EuBIVAS may be beneficial for the diagnosis and management of parathyroid glands and bone turnover pathologies.

Impacto de la fractura de cadera intervenida quirúrgicamente sobre la calidad de vida, el estado funcional y el estado de ánimo del anciano / Impact of surgically operated hip fracture on the quality of life, functional status and mood of the elderly

OBJETIVO: Determinar la calidad de vida relacionada con la salud, la capacidad funcional y el estado de ánimo previo a la fractura de cadera y al mes de la intervención quirúrgica. MÉTODO: Estudio descriptivo prospectivo desarrollado desde enero de 2015 a enero de 2016 en el Hospital Campo Arañuelo (Navalmoral de la Mata, Cáceres). Se recogieron variables sociodemográficas, capacidad funcional (índice de Barthel), dependencia (escala de Lawton y Brody), calidad de vida relacionada con la salud (cuestionario Euroqol-5D) y estado de ánimo (escala de depresión geriátrica de Yesavage) con anterioridad a la fractura de cadera y al mes de la intervención. RESULTADOS: En 96 pacientes mayores de 65años se produjo un descenso significativo de la capacidad funcional: la media fue de 86,66 antes de la fractura frente a 58,72 al mes de la intervención (p < 0,001). La dependencia media fue de 4,95, y al mes, de 2,24 (p < 0,001). Las puntuaciones medias sobre calidad de vida basal y posterior a la intervención en EQ-5D fue de 72,95 vs 59,45, respectivamente (p = 0,004). Aunque antes de la fractura el 94,10% no tenían alteración del estado de ánimo, al mes de la intervención presentaban probable depresión el 20,50% y depresión establecida el 11%. CONCLUSIONES: La fractura de cadera afecta a la funcionalidad de los ancianos y provoca dependencia para las actividades básicas e instrumentales de la vida diaria. También afecta a la calidad de vida, y esta disminuye de forma significativa al mes de la intervención quirúrgica. El estado de ánimo depresivo está inversamente relacionado con la calidad de vida percibida

OBJECTIVES: To determine the quality of life related to health, functional capacity and mood to hip fracture and one month after surgery. METHOD: Prospective and descriptive study developed from January 2015 to January 2016 in Campo Arañuelo Hospital (Navalmoral de la Mata, Cáceres, Spain). Sociodemographic variables, functional capacity (Barthel Index), dependence (Lawton and Brody Scale), quality of life related to health (Questionnaire Euroqol-5D) and on mood (Yesavage geriatric depression scale GDS15) were collected, prior to the hip fracture and one month after the intervention. RESULTS: Significant decrease in functional capacity (Barthel), the mean score was 86.66 before the fracture, compared to 58.72 at the month after surgery (P<.001). Regarding the Lawton and Brody Scale, the mean was 4.95 and at 2.24months (P<.001). The mean scores on health related quality of life, baseline and post-intervention in the analog visual scale of the EQ-5D questionnaire were 72.95 vs 59.45 respectively (P=.004). Although before the fracture, 94.10% had no alteration in mood, one month after the intervention there was a possible depression of 20.50% and an established depression of 11%. CONCLUSIONS: The fracture of the head affects the functionality of the elderly, causing dependence for the basic and instrumental activities of daily life. It also affects the quality of life related to health and this decreases significantly in the month after surgery. Depressive mood is inversely related to perceived perceived quality of life

Analytical Performance Specifications for Lipoprotein(a), Apolipoprotein B-100, and Apolipoprotein A-I Using the Biological Variation Model in the EuBIVAS Population.

BACKGROUND: With increased interest in lipoprotein(a) (Lp[a]) concentration as a target for risk reduction and growing clinical evidence of its impact on cardiovascular disease (CVD) risk, rigorous analytical performance specifications (APS) and accuracy targets for Lp(a) are required. We investigated the biological variation (BV) of Lp(a), and 2 other major biomarkers of CVD, apolipoprotein A-I (apoA-I) and apolipoprotein B-100 (apoB), in the European Biological Variation Study population. METHOD: Serum samples were drawn from 91 healthy individuals for 10 consecutive weeks at 6 European laboratories and analyzed in duplicate on a Roche Cobas 8000 c702. Outlier, homogeneity, and trend analysis were performed, followed by CV-ANOVA to determine BV estimates and their 95% CIs. These estimates were used to calculate APS and reference change values. For Lp(a), BV estimates were determined on normalized concentration quintiles. RESULTS: Within-subject BV estimates were significantly different between sexes for Lp(a) and between women aged <50 and >50 years for apoA-I and apoB. Lp(a) APS was constant across concentration quintiles and, overall, lower than APS based on currently published data, whereas results were similar for apoA-I and apoB. CONCLUSION: Using a fully Biological Variation Data Critical Appraisal Checklist (BIVAC)-compliant protocol, our study data confirm BV estimates of Lp(a) listed in the European Federation of Clinical Chemistry and Laboratory Medicine database and reinforce concerns expressed in recent articles regarding the suitability of older APS recommendations for Lp(a) measurements. Given the heterogeneity of Lp(a), more BIVAC-compliant studies on large numbers of individuals of different ethnic groups would be desirable.

Condiciones laborales, salud y calidad de vida en conductores / Working Conditions, Health and Quality of Life among Drivers / Condições de trabalho, saúde e qualidade de vida em motoristas

Objetivo: Conocer las condiciones laborales, salud y calidad de vida de los trabajadores que se dedican al rubro de la conducción. Materiales y Métodos: Se realizó revisión integrativa en las bases de datos Medline/PUBMED, BVS, WEB OF SCIENCE, SCOPUS, referente a artículos publicados desde el año 2010 a 2019, en relación a la temática de salud, condiciones laborales y calidad de vida de trabajadores que se desempeñan en el área de la conducción, siguiendo los lineamientos planteados según Ganong. Resultados: 29 estudios cumplieron con los criterios seleccionados, los cuales fueron realizados en población trabajadora del ámbito de locomoción colectiva como buses, taxis, motocicletas y en el área de transportes, como camiones. Discusión: La realidad que experimentan estos trabajadores crea consciencia y abre un espacio para implementar políticas de salud que busquen su bienestar, y a la vez es una puerta de entrada a crear conocimiento sobre la necesidad de estudiar a este grupo poblacional. Conclusiones: La calidad de vida y las condiciones laborales de estos conductores, en su mayoría es deficiente y esto los afecta de manera negativa en distintos ámbitos. Por otra parte, la salud de este grupo de trabajadores se ve perjudicada por las condiciones en el trabajo que muchos de ellos puedan tener, así mismo la mayoría carece de buenas prácticas de salud, teniendo hábitos poco saludables, que se relacionan directamente con la labor que realizan.

Objetive: This study is aimed to determine the working conditions, health and quality of life of workers involved in the driving industry. Materials and Methods: An integrative review was carried out in the Medline/PubMed, VHL, Web of Science, and Scopus databases, referring to articles related to working conditions, health, and quality of life of workers in the driving industry which had been published between 2010 and 2019, following the guidelines set forth by Ganong. Results: 29 studies met the selected criteria, which were conducted in the driver population working in the area of means of transport such as buses, taxis, motorcycles and the area of cargo transport such as trucks. Discussion: The reality experimented by these workers creates awareness and opens up a space to implement healthcare policies that seek their wellbeing, and at the same time, it is a gateway to creating knowledge about the need to study this population group. Conclusions: The quality of life and working conditions of these drivers are mostly inadequate, affecting them negatively in different ways. Moreover, the health of this group of workers is getting affected by the working conditions that many of them may have, and most of them lack good health practices, having unhealthy habits that are directly related to the work they do.

Objetivo: Conhecer as condições de trabalho, a saúde e a qualidade de vida dos trabalhadores dedicados ao campo da direção. Materiais e Métodos: Foi realizada uma revisão integrativa nas bases de dados Medline/PubMed, BVS, Web of Science, Scopus, referente a artigos publicados de 2010 a 2019, em relação à saúde, condições de trabalho e qualidade de vida de trabalhadores que trabalham na área de direção, seguindo as diretrizes estabelecidas de acordo com Ganong. Resultados: 29 estudos atenderam aos critérios selecionados, realizados na população trabalhadora no campo da locomoção coletiva, como ônibus, táxis, motocicletas e na área de transporte, como caminhões. Discussão: A realidade vivenciada por esses trabalhadores gera conscientização e abre espaço para a implementação de políticas de saúde que busquem seu bem-estar e, ao mesmo tempo, é uma porta de entrada para a criação de conhecimento sobre a necessidade de estudar esse grupo populacional. Conclusões: A qualidade de vida e as condições de trabalho desses motoristas são principalmente ruins e isso os afeta negativamente em diferentes áreas. Por outro lado, a saúde desse grupo de trabalhadores é prejudicada pelas condições de trabalho que muitos deles podem ter, assim como a maioria carece de boas práticas de saúde, possuindo hábitos pouco saudáveis, diretamente relacionados ao trabalho que realizam.

Impact of surgically operated hip fracture on the quality of life, functional status and mood of the elderly. / Impacto de la fractura de cadera intervenida quirúrgicamente sobre la calidad de vida, el estado funcional y el estado de ánimo del anciano.

OBJECTIVES: To determine the quality of life related to health, functional capacity and mood to hip fracture and one month after surgery. METHOD: Prospective and descriptive study developed from January 2015 to January 2016 in Campo Arañuelo Hospital (Navalmoral de la Mata, Cáceres, Spain). Sociodemographic variables, functional capacity (Barthel Index), dependence (Lawton and Brody Scale), quality of life related to health (Questionnaire Euroqol-5D) and on mood (Yesavage geriatric depression scale GDS15) were collected, prior to the hip fracture and one month after the intervention. RESULTS: Significant decrease in functional capacity (Barthel), the mean score was 86.66 before the fracture, compared to 58.72 at the month after surgery (P<.001). Regarding the Lawton and Brody Scale, the mean was 4.95 and at 2.24months (P<.001). The mean scores on health related quality of life, baseline and post-intervention in the analog visual scale of the EQ-5D questionnaire were 72.95 vs 59.45 respectively (P=.004). Although before the fracture, 94.10% had no alteration in mood, one month after the intervention there was a possible depression of 20.50% and an established depression of 11%. CONCLUSIONS: The fracture of the head affects the functionality of the elderly, causing dependence for the basic and instrumental activities of daily life. It also affects the quality of life related to health and this decreases significantly in the month after surgery. Depressive mood is inversely related to perceived perceived quality of life.