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Poumon Coeur ; 33(4): 235-41, 1977.
Article in French | MEDLINE | ID: mdl-72386

ABSTRACT

The study of 9 cases of agammaglobulinemia in the adult shows the classical symptomatology of these diseases. The evolutive study deals with too small a series to demonstrate statistically the superiority of the substitutive treatment over a simple chemo-therapeutic prevention of the infection, but nevertheless it shows : 1) that prognosis is bad only in cases of gross anatomical and physiological alterations and when they are the sole responsible for a fatal evolution; 2) that the substitutive treatment is only really efficient when given at high doses; the minimum dose of 250 mg per day seems advisable.


Subject(s)
Agammaglobulinemia/drug therapy , gamma-Globulins/administration & dosage , Adolescent , Adult , Antibodies/therapeutic use , Dose-Response Relationship, Immunologic , Female , Humans , Injections, Intramuscular , Injections, Intravenous , Lung Diseases/prevention & control , Male , Middle Aged
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