1.
Molecules
; 21(9)2016 Aug 30.
Article
in English
| MEDLINE
| ID: mdl-27589710
ABSTRACT
Four new mexicanolide-type limonoids 1-4, along with two known limonoids 5-6, were isolated from the ethanolic extracts of roots of the Traditional Chinese Medicine Trichilia sinensis. Their structures were unambiguously determined by analysis of spectroscopic data, including 1D and 2D NMR as well as MS, and by comparison with literature data. In addition, the acetylcholinesterase (AChE) inhibitory activity of compounds 1-6 was evaluated by the Ellman method. All these compounds showed weak AChE inhibitory activity, with the inhibition percentages ranging from 18.5% to 27.8%.
Subject(s)
Cholinesterase Inhibitors , Limonins , Meliaceae/chemistry , Plant Roots/chemistry , Cholinesterase Inhibitors/chemistry , Cholinesterase Inhibitors/isolation & purification , Limonins/chemistry , Limonins/isolation & purification , Magnetic Resonance Spectroscopy , Molecular Structure
2.
Magn Reson Chem
; 54(11): 916-921, 2016 11.
Article
in English
| MEDLINE
| ID: mdl-27400676
Subject(s)
Ascomycota/chemistry , Furans/chemistry , Neuroprotective Agents/chemistry , Animals , Apoptosis/drug effects , Furans/isolation & purification , Furans/pharmacology , Hydrogen Peroxide/pharmacology , Magnetic Resonance Spectroscopy/standards , Molecular Structure , Neuroprotective Agents/isolation & purification , Neuroprotective Agents/pharmacology , Orthoptera , PC12 Cells , Rats , Reference Standards
3.
Magn Reson Chem
; 53(4): 317-22, 2015 Apr.
Article
in English
| MEDLINE
| ID: mdl-25594922