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1.
Pediatr Blood Cancer ; 69(7): e29686, 2022 07.
Article in English | MEDLINE | ID: mdl-35353440

ABSTRACT

Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an effective strategy to prevent serious coronavirus disease 2019 (COVID-19) and is important for oncology patients. mRNA-based COVID-19 vaccines are contraindicated in those with a history of severe or immediate allergy to any vaccine component, including polyethylene glycol (PEG)2000. Patients with acute lymphoblastic leukemia/lymphoma receive asparaginase conjugated to PEG5000 (PEG-ASNase) and those with PEG-ASNase-associated hypersensitivity may be unnecessarily excluded from receiving mRNA COVID-19 vaccines. We, therefore, surveyed oncologists on COVID-19 vaccine counseling practice and vaccination outcomes in COVID-19 vaccination-eligible patients and show safe receipt of mRNA vaccines despite PEG-ASNase hypersensitivity.


Subject(s)
Asparaginase , COVID-19 Vaccines , COVID-19 , Drug Hypersensitivity , Polyethylene Glycols , Asparaginase/adverse effects , COVID-19/prevention & control , COVID-19 Vaccines/administration & dosage , COVID-19 Vaccines/adverse effects , Counseling , Drug Hypersensitivity/etiology , Humans , Oncologists , Polyethylene Glycols/adverse effects , RNA, Messenger , SARS-CoV-2 , Vaccination/adverse effects
2.
Adv Ther ; 37(5): 2224-2235, 2020 05.
Article in English | MEDLINE | ID: mdl-32274750

ABSTRACT

INTRODUCTION: Despite improved understanding of the risks of influenza and better vaccines for older patients, influenza vaccination rates remain subpar, including in high-risk groups such as older adults, and demonstrate significant racial and ethnic disparities. METHODS: This study considers demographic, clinical, and geographic correlates of influenza vaccination among Medicare Fee-for-Service (FFS) beneficiaries in 2015-2016 and maps the data on a geographic information system (GIS) at the zip code level. RESULTS: Analyses confirm that only half of the senior beneficiaries evidenced a claim for receiving an inactivated influenza vaccine (IIV), with significant disparities observed among black, Hispanic, rural, and poorer beneficiaries. More extensive disparities were observed for the high-dose (HD) vaccine, with its added protection for older populations and confirmed economic benefit. Most white beneficiaries received HD; no non-white subgroup did so. Mapping of the data confirmed subpar vaccination in vulnerable populations with wide variations at the zip code level. CONCLUSION: Urgent and targeted efforts are needed to equitably increase IIV rates, thus protecting the most vulnerable populations from the negative health impact of influenza as well as the tax-paying public from the Medicare costs from failing to do so.


Subject(s)
Healthcare Disparities/statistics & numerical data , Influenza Vaccines/administration & dosage , Influenza, Human/prevention & control , Patient Acceptance of Health Care/psychology , Patient Acceptance of Health Care/statistics & numerical data , Vaccination/psychology , Vaccination/statistics & numerical data , Black or African American/psychology , Black or African American/statistics & numerical data , Age Factors , Aged , Aged, 80 and over , Ethnicity/psychology , Ethnicity/statistics & numerical data , Fee-for-Service Plans/statistics & numerical data , Female , Hispanic or Latino/psychology , Hispanic or Latino/statistics & numerical data , Humans , Influenza, Human/epidemiology , Male , Medicare/statistics & numerical data , United States/epidemiology , White People/psychology , White People/statistics & numerical data
3.
Psychiatr Serv ; 56(5): 551-6, 2005 May.
Article in English | MEDLINE | ID: mdl-15872163

ABSTRACT

OBJECTIVES: Structural stigma and discrimination occur when an institution like a newspaper, rather than an individual, promulgates stigmatizing messages about mental illness. This study examined current trends in the news media on reporting topics of mental illness. METHODS: All relevant stories (N=3,353) in large U.S. newspapers were identified and coded during six weeklong periods in 2002. Stories were coded by themes that fit into four categories: dangerousness, blame, treatment and recovery, and advocacy action (that is, calls for public policy and action that increase the quality of care or opportunities for those with mental illness). RESULTS: Thirty-nine percent of all stories focused on dangerousness and violence; these stories most often ended up in the front section. Few stories promulgated the idea that either the person or the family was responsible for mental illness (2 percent). Instead, stories about genetic or biological or environmental causation (for example, stress and trauma) were more common (15 percent). There were equal numbers of stories about biological and psychosocial treatments (13 and 14 percent, respectively). Four percent of all treatment-related stories addressed recovery. Twenty percent of stories contained themes that fell into the broad category of advocacy action. These stories addressed the shortage of resources in the public mental health arena, the need for better care, the absence of good-quality housing, and the goal of insurance parity. CONCLUSIONS: Data on how mental illness is represented in newspapers yield a useful perspective on structural stigma and the policies and standards that are applied by the news media. These findings have implications for influencing the press.


Subject(s)
Mental Disorders/psychology , Newspapers as Topic/statistics & numerical data , Stereotyping , Humans , Prejudice , United States
4.
Psychiatr Serv ; 56(5): 557-63, 2005 May.
Article in English | MEDLINE | ID: mdl-15872164

ABSTRACT

OBJECTIVE: This article discusses examples of structural stigma that results from state governments' enactment of laws that diminish the opportunities of people with mental illness. METHODS: To examine current trends in structural stigma, the authors identified and coded all relevant bills introduced in 2002 in the 50 states. Bills were categorized in terms of their effect on liberties, protection from discrimination, and privacy. The terms used to describe the targets of bills were examined: persons with "mental illness" or persons who are "incompetent" or "disabled" because of mental illness. RESULTS: About one-quarter of the state bills reviewed for this survey related to protection from discrimination. Within that category, half the bills reduced protections for the targeted individuals, such as restriction of firearms for people with current or past mental illness and reduced parental rights among persons with a history of mental illness. Half the bills seemed to expand protections, such as those that required mental health funding at the same levels provided for other medical conditions and those that disallowed use of mental health status in child custody cases. Legislation frequently confuses "incompetence" with "mental illness." CONCLUSIONS: Examples of structural stigma uncovered by surveys such as this one can inform advocates for persons with mental illness as to where an individual state stands in relation to the number of bills that affect persons with mental illness and whether these bills expand or contract the liberties of this stigmatized group.


Subject(s)
Human Rights/legislation & jurisprudence , Mental Disorders/psychology , State Government , Stereotyping , Humans , United States
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