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J Wildl Dis ; 54(4): 819-824, 2018 10.
Article in English | MEDLINE | ID: mdl-29863971

ABSTRACT

Decreased access to potent narcotics for wildlife applications has stimulated the need to explore alternative drug combinations for ungulate immobilizations. A combination of butorphanol, azaperone, and medetomidine (BAM) has been used for some ungulate species, but information on its use in bison ( Bison bison) is limited. We conducted field trials using BAM, in conjunction with atipamezole and naltrexone as antagonists, for reversible field immobilization of bison during ground- and helicopter-based operations. We compared times to induction and recovery, vital rates (rectal temperature and respiration rate), and the quality of induction, immobilization, and recovery between ground- and helicopter-based immobilizations of bison. Overall, 15 of 21 bison were induced with the volume we used (mean±SD=3.4±0.6 mL); two other animals darted from a helicopter required a full second dose, and four others (two darted from the ground and two from a helicopter) required a supplemental partial dose to achieve induction. All immobilizations achieved a sufficient plane of anesthesia to permit minor invasive procedures (e.g., skin biopsy and blood sampling). All animals recovered, and most (17 of 21) were reversed in ≤5 min. The mean time to induction was 10.8±7.3 min while that for recovery was 5.0±2.1 min. We found few differences in vital rates or the quality of immobilizations between ground- and helicopter-based captures. The drug combination provided good immobilization and was reliably reversed; however, inconsistent inductions at the doses we used may limit its use in field immobilizations of bison, particularly those animals being darted from a helicopter.


Subject(s)
Anesthetics, Combined/pharmacology , Azaperone/pharmacology , Bison/physiology , Butorphanol/pharmacology , Immobilization/veterinary , Medetomidine/pharmacology , Analgesics, Opioid/administration & dosage , Analgesics, Opioid/pharmacology , Anesthetics, Combined/administration & dosage , Animals , Animals, Wild , Azaperone/administration & dosage , Butorphanol/administration & dosage , Drug Combinations , Female , Hypnotics and Sedatives/pharmacology , Male , Medetomidine/administration & dosage
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