ABSTRACT
ABSTRACT Coronavirus disease (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its main form of transmission is through respiratory droplets. Case reports have described the presence of this virus in biological materials such as blood, feces, urine, and tears, which generate hypotheses about other means thereby the disease is transmitted. In this report, we describe a case of SARS-CoV-2 identified on the eye surface of an asymptomatic health-care professional. The nasopharyngeal reverse transcription polymerase chain reaction test, using a sample collected on the same day, and the serological test, performed 3 months later, did not reveal any evidence of SARS-CoV-2 infection. These results alert on the possibility of a false-positive reverse transcription polymerase chain reaction result for the ocular surface or the presence of the virus in the conjunctival mucosa in individuals without infection.
RESUMO A COVID-19 é uma doença infeciosa causada pelo SARS-CoV-2, sendo sua principal forma de transmissão através de gotículas respiratórias. Já existem relatos de caso descrevendo a presença desse vírus em materiais biológicos como sangue, fezes, urina e lágrima, o que gera hipóteses sobre outros meios de transmissão da doença. Neste estudo, descrevemos um caso de identificação do vírus SARS-CoV-2 na superfície ocular de um profissional de saúde assintomático. A transcrição inversa da reação em cadeia da polimerase da nasofaringe, coletada no mesmo dia, e o teste sorológico, realizado três meses após, não detectaram qualquer evidência de infecção pelo SARS-CoV-2. Esses dados alertam para a possibilidade de resultado falso positivo da transcrição inversa da reação em cadeia da polimerase da superfície ocular ou a presença do vírus na mucosa conjuntival sem infecção.
ABSTRACT
Purpose: To report a case of multiple bilateral retinal pigment epithelial detachments (PEDs) in a woman with systemic lupus erythematosus (SLE). Methods: Case Report. Results: A 28-year-old female with mild blurred bilateral vision in both eyes (OU) without pain or any other symptom was admitted to the hospital due to worsening renal function and uncontrolled high blood pressure (HBP). Best-corrected visual acuity (BCVA) was 20/30 and 20/40, right and left eyes, respectively. She had SLE, glucose-6-phosphate dehydrogenase deficiency, and immune thrombocytopenic purpura. BP was over 150/90 mmHg for more than 1.5 years, and she used corticosteroids at varying doses for more than 4 years. During hospitalization, she was taking prednisone 60 mg daily as Class IV lupus nephritis was diagnosed. On fundoscopy, she had a lacy retinal pattern, remarkably on the macula in OU. Spectral-domain optical coherence tomography revealed multiple bilateral serous PEDs and pachychoroid. Angiofluoresceinography displayed multiple pooling hyperfluorescence areas. Six months afterward, while she was on prednisolone 10 mg daily, and antihypertensive medications, BCVA was improved to 20/25 OU. Nevertheless, she had no retinal or choroidal changes. Her findings could be related to SLE choroidopathy, central serous chorioretinopathy-like disease, and/or hypertensive choroidopathy. Conclusions: Ocular involvement affects nearly one-third of SLE patients. The findings are variable and can include nearly any part of the eyeball. Multiple bilateral PEDs have been described in the literature; however, in this case, it is probably multifactorial and not only related to SLE.
ABSTRACT
Coronavirus disease (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its main form of transmission is through respiratory droplets. Case reports have described the presence of this virus in biological materials such as blood, feces, urine, and tears, which generate hypotheses about other means thereby the disease is transmitted. In this report, we describe a case of SARS-CoV-2 identified on the eye surface of an asymptomatic health-care professional. The nasopharyngeal reverse transcription polymerase chain reaction test, using a sample collected on the same day, and the serological test, performed 3 months later, did not reveal any evidence of SARS-CoV-2 infection. These results alert on the possibility of a false-positive reverse transcription polymerase chain reaction result for the ocular surface or the presence of the virus in the conjunctival mucosa in individuals without infection.
ABSTRACT
Introdução: A adoção de práticas sustentáveis pode ser entendida como uma ação rumo a um consumo sustentável, diretamenteconectado às práticas cotidianas. Entendendo a necessidade de uma ação contínua e participativa, as Faculdades Integradas Padre Albino(FIPA) lançaram o Manual de Práticas Sustentáveis. Objetivos: Avaliar o conhecimento dos alunos do curso de Medicina sobre o Manual esua adesão às ações nele recomendadas. Material e Método: Estudo transversal, descritivo, realizado através da aplicação de questionárioaos alunos de todas as séries do curso de Medicina das FIPA, de Catanduva-SP, no período de junho a outubro/2016. As variáveisanalisadas foram: série em curso, idade, sexo e 13 questões relacionadas à prática de ações recomendadas no Manual e 01 ao seuconhecimento e leitura. Os resultados foram expressos em número, porcentagem, média e desvio-padrão. Resultados: Os participantesrepresentaram 89,1% dos matriculados, sendo 59,9% mulheres. A média de idade foi 23±3,2 anos e 86,8% desconheciam o Manual.Declararam ter preocupação diária de: economizar água (81,3%), economizar energia elétrica (84,8%), comprar eletrodomésticos maiseconômicos (73,4%), optar pelo uso de combustível mais econômico (64%), praticar carona solidária (70,2%), resolver assuntos evitandodeslocamentos desnecessários (85,4%), usar mídias regraváveis (79,2%), evitar imprimir material desnecessário (59,9%), evitar trocarequipamentos eletrônicos em bom estado (44,1%), preservar a vegetação (83%), evitar usar material descartável (26,9%), separar lixopara reciclagem (35,3%) e evitar usar sacolas descartáveis (22,5%). Conclusões: embora os alunos declarem não terem conhecimentodo Manual, em seu cotidiano, geralmente praticam as ações de sustentabilidade ambiental recomendadas nele.
Introduction: The adoption of sustainable practices can be understood as an action towards a sustainable consumption, directly connectedto daily practices. Understanding the need for a continuous and participatory action, the Integrated Faculties Padre Albino (FIPA), havelaunched the "Manual of Sustainable Practices". Objectives: To evaluate the medical students' knowledge about the Manual and theiradherence to the recommended actions. Material and Method: It was a a cross-sectional, descriptive study conducted through theapplication of a questionnaire to students of all the FIPA medical series, from Catanduva-SP, from June through October 2016. Theanalyzed variables were: current series, age, sex and 13 questions related to the practice of actions recommended in the Manual, as well01 to their knowledge and reading. The results were expressed in number, percentage, mean and standard deviation. Results: Participantsaccounted for 89.1% of the enrolled, being women 59.9% of them. The mean age was 23 ± 3.2 years and 86.8% were unaware ofthe Manual. They stated that they had a daily worry of saving water (81.3%), saving electricity (84.8%), buying more economicalappliances (73.4%), choosing to use cheaper fuel (64%), giving rides one to the other (70.2%), solving problems avoiding unnecessarydisplacements (85.4%), using rewritable media (79.2%), avoiding printing unnecessary material (59.9%), avoiding changing electronicequipment in good condition (1%), preserving vegetation (83%), avoiding using disposable material (26.9%), separating garbage forrecycling (35.3%) and avoiding using disposable bags (22.5%). Conclusions: Although students declare not knowing the Manual, theygenerally practice the environmental sustainability actions recommended in it.
Introducción: La adopción de prácticas sostenibles puede ser entendida como una acción hacia un consumo sustentable, directamenteconectado a las prácticas cotidianas. Entendiendo la necesidad de una acción continua y participativa, las Facultades Integradas PadreAlbino (FIPA) lanzaron el "Manual de Prácticas Sostenibles". Objetivos: Evaluar el conocimiento de los alumnos del curso de Medicinasobre el Manual y su adhesión a las acciones en él recomendadas. Material y método: Estudio transversal, descriptivo, realizado a travésde la aplicación de cuestionario a los alumnos de todas las series del curso de Medicina de las FIPA, de Catanduva-SP, en el período dejunio a octubre / 2016. Las variables analizadas fueron: serie en curso, edad, sexo y 13 cuestiones relacionadas a la práctica de accionesrecomendadas en el Manual y 01 a su conocimiento y lectura. Los resultados se expresaron en número, porcentaje, media y desviaciónestándar. Resultados: Los participantes representaron el 89,1% de los matriculados, siendo 59,9% mujeres. El promedio de edad fuede 23 ± 3,2 años y el 86,8% desconocía el Manual. Informó preocupación diaria: ahorrar agua (81.3%), ahorrar electricidad (84.8%),comprar electrodomésticos más económicos (73,4%), optar por el uso de combustible más económico (64%), compartir (70.2%), laresolución de problemas evitando desplazamientos innecesarios (85,4%), usar los medios regrabables (79,2%), evitar la impresión dematerial innecesario (59,9%), evitar el intercambio de equipos electrónicos en buen estado (44 , 1%) preservar la vegetación (83%)para evitar el uso de material desechable (26,9%), residuos por separado para su reciclaje (35,3%) y evitar el uso de bolsas desechables(22,5%). Conclusiones: Aunque los alumnos declaran no tener conocimiento del Manual, en su cotidiano, generalmente practican lasacciones de sustentabilidad ambiental recomendadas en él.
