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1.
Br J Anaesth ; 132(5): 849-850, 2024 May.
Article in English | MEDLINE | ID: mdl-38538514

ABSTRACT

Patients who undergo laparotomy for major trauma are amongst the most critically unwell patients, and they have high morbidity and mortality rates. Despite 20 yr of improvements in resuscitation practices, those who present with hypotension continue to have mortality rates of up to 50%. Currently there is no mechanism for capturing national audit data on these patients, leading to their exclusion from potential quality improvement initiatives. We argue that there is an unmet need for quality assurance in this patient cohort and outline possible mechanisms to address this.


Subject(s)
Hypotension , Laparotomy , Humans , Medical Audit , Quality Improvement , United Kingdom , Retrospective Studies
2.
Eur J Trauma Emerg Surg ; 48(2): 1453-1461, 2022 Apr.
Article in English | MEDLINE | ID: mdl-34132821

ABSTRACT

PURPOSE: The burden of major trauma within the UK is ever increasing. There is a need to establish research priorities within the field. Delphi methodology can be used to develop consensus opinion amongst a group of stakeholders. This can be used to prioritise clinically relevant, patient-centred research questions to guide future funding allocations. The aim of our study was to identify key future research priorities pertaining to the management of major trauma in the UK. METHODS: A three-phased modified Delphi process was undertaken. Phase 1 involved the submission of research questions by members of the trauma community using an online survey (Phase 1). Phases 2 and 3 involved two consecutive rounds of prioritisation after questions were subdivided into 6 subcategories: Brain Injury, Rehabilitation, Trauma in Older People, Pre-hospital, Interventional, and Miscellaneous (Phases 2 and 3). Cut-off points were agreed by consensus amongst the steering subcommittees. This established a final prioritised list of research questions. RESULTS: In phase 1, 201 questions were submitted by 65 stakeholders. After analysis and with consensus achieved, 186 questions were taken forward for prioritisation in phase 2 with 114 included in phase 3. 56 prioritised major trauma research questions across the 6 categories were identified with a clear focus on long-term patient outcomes. Research priorities across the patient pathway from roadside to rehabilitation were deemed of importance. CONCLUSIONS: Consensus within the major trauma community has identified 56 key research questions across 6 categories. Dissemination of these questions to funding bodies to allow for the development of high-quality research is now required. There is a clear indication for targeted multi-centre multi-disciplinary research in major trauma.


Subject(s)
Biomedical Research , Aged , Consensus , Delphi Technique , Humans , Surveys and Questionnaires
4.
Interact Cardiovasc Thorac Surg ; 10(5): 803-4, 2010 May.
Article in English | MEDLINE | ID: mdl-20067987

ABSTRACT

Ewing's sarcoma is a neuroectodermal tumour characteristically presenting during the second decade of life and arising from bone. Extraskeletal Ewing's sarcoma is exceptionally rare. We present a case of a 44-year-old man who underwent pneumonectomy for a primary extraskeletal Ewing's sarcoma of the lung. This demonstrates a very rare pulmonary Ewing's sarcoma and highlights the importance of preoperative evaluation in aggressive tumours.


Subject(s)
Brain Neoplasms/secondary , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Sarcoma, Ewing/secondary , Sarcoma, Ewing/surgery , Adult , Biopsy, Needle , Brain Neoplasms/drug therapy , Brain Neoplasms/pathology , Chemotherapy, Adjuvant , Disease Progression , Fatal Outcome , Humans , Immunohistochemistry , Lung Neoplasms/diagnosis , Male , Neoplasm Staging , Pneumonectomy/methods , Positron-Emission Tomography , Sarcoma, Ewing/diagnosis , Tomography, X-Ray Computed
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