1.
Agents Actions
; 13(4): 301-9, 1983 Jun.
Article
in English
| MEDLINE
| ID: mdl-6193695
Subject(s)
Cromolyn Sodium/pharmacology , Mast Cells/drug effects , Muscle Contraction/drug effects , Muscle Relaxation/drug effects , Muscle, Smooth/drug effects , Triazoles/pharmacology , Animals , Guinea Pigs , Histamine Release/drug effects , Immunoglobulin E/immunology , Lung/immunology , Male , Passive Cutaneous Anaphylaxis , Rats , Rats, Inbred Strains
2.
Monogr Allergy
; 18: 223-5, 1983.
Article
in English
| MEDLINE
| ID: mdl-6196629
3.
Int Arch Allergy Appl Immunol
; 59(4): 437-42, 1979.
Article
in English
| MEDLINE
| ID: mdl-87383
ABSTRACT
Rats actively sensitised to bovine serum albumin (BSA) in Freund's complete adjuvant were challenged by intraperitoneal injection of BSA. By washing out the peritoneal cavities at different times it was possible to divide the changes that occurred into two phases. The first was characterised by the release of histamine and slow reacting substance of anaphylaxis (SRS-A) with an associated extravasation of plasma proteins. The second phase was characterised by an increase in neutrophilic polymorphonuclear cells in the peritoneal cavity. Extracellular enzyme activites were also investigated. The kinetics of these events were studied and are discussed in terms of the possible mechanisms involved.