Neonatal Appendicitis With Necrotizing Enterocolitis.

Acute appendicitis is an infrequent condition in neonates, especially in term infants. With around 100 cases in the last century and no specific diagnostic tool, this case report is an addition to the existing literature that helps in our understanding of the disease. A preterm infant who had greenish aspirates and dilated bowel loops on abdominal x ray and was treated on the lines of necrotizing enterocolitis failed to improve. Baby had issues of abdominal distension whenever feeds were started hence exploratory laparotomy was done on the 45th day of life which showed appendicitis with adherent terminal ileum, caecum, and appendix. Two months after the surgery, the patient was unable to respond to antibiotic therapy for septic condition leading to death.

A case report on fibular aplasia, tibial campomelia, oligosyndactyly syndrome variant in a male infant.

Fibular aplasia, tibial campomelia, and oligosyndactyly (FATCO syndrome) is a rare, genetic, congenital limb malformation characterised by unilateral or bilateral fibular aplasia, tibial campomelia, and lower limb oligosyndactyly involving the lateral rays. A newborn male born at term via a Caesarean Section presented with malformations consisting of tibial campomelia, unilateral fibular hypoplasia, and oligosyndactyly, a "FATCO variant" case. On radiographic examination, an anterolateral shortened and bowed right lower limb at the distal third of the tibia, a rudimentary right fibula and absence of three rays on right foot were revealed. "FATCO syndrome" although rare may be linked to involvement of different body systems with morbidity and mortality. Proper parent counseling is a key aspect of this syndrome. Timely diagnosis and management with a multidisciplinary approach is essential to avoid lifelong disability, which can be a hurdle in a developing country.

Insight into the Knowledge, Attitude, Practices, and Barriers Concerning Organ Donation Amongst Undergraduate Students of Pakistan.

BACKGROUND: In Pakistan, thousands are reported dead due to organ failure annually, owing to the huge discrepancy between the number of people waiting for organ donation and the number of organs available. It is imperative that the young generation, the future donor force, comprehends the concept and importance of organ donation. Hence, this study was conducted to assess the knowledge, attitude, and practices regarding organ donation amongst the youth of Pakistan, and to delineate the factors that motivate or demotivate the new generation for organ donation so our future campaigns may be more successful.  Methods: A cross-sectional study was conducted on undergraduate medical and non-medical students from various universities of Karachi, Pakistan. Using convenience sampling, 450 students were sent online, structured, 11-item questionnaires. The analysis was conducted using Statistical Package for Social Sciences (SPSS version 23.0, IBM Corp., Armonk, NY, US), and associations calculated through chi-square tests. A knowledge score was calculated to reflect a participant's familiarity with organ donation.  Results: 88.7% of students were familiar with organ donation; however, only 34.6% were willing to donate, and 0.6% had donated an organ. Belonging to a medical university and female gender were associated with higher knowledge scores. 'To save lives' (51.7%) was cited by most students as a factor that would motivate them to donate an organ, while 'Religion' (27.6%) was chosen as the most popular factor that demotivates them. CONCLUSION: Majority of the students had insufficient overall knowledge about organ donation, highlighting the need for inculcating this topic in the curriculum. The differences in knowledge between medical and non-medical students were inconsistent with their practices, indicating that future campaigns should focus on eliminating barriers to organ donation to facilitate an accepting attitude and increased practices with respect to this topic.