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J Cardiovasc Pharmacol ; 78(3): 336-345, 2021 09 01.
Article in English | MEDLINE | ID: mdl-34117179

ABSTRACT

ABSTRACT: Inotropes and inopressors are often first-line treatment in patients with cardiogenic shock. We summarize the pharmacology, indications, and contraindications of dobutamine, milrinone, dopamine, norepinephrine, epinephrine, and levosimendan. We also review the data on the use of these medications for acute decompensated heart failure and cardiogenic shock in this article.


Subject(s)
Cardiotonic Agents/therapeutic use , Heart Failure/drug therapy , Hemodynamics/drug effects , Myocardial Contraction/drug effects , Shock, Cardiogenic/drug therapy , Vasoconstrictor Agents/therapeutic use , Cardiotonic Agents/adverse effects , Contraindications, Drug , Heart Failure/diagnosis , Heart Failure/physiopathology , Humans , Recovery of Function , Shock, Cardiogenic/diagnosis , Shock, Cardiogenic/physiopathology , Treatment Outcome , Vasoconstrictor Agents/adverse effects
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