1.
Fitoterapia
; : 106000, 2024 May 08.
Article
in English
| MEDLINE
| ID: mdl-38729248
ABSTRACT
Five new characteristic cembrane-type diterpenoids (olibacartiols A-E, 1-5) were acquired from the gum resin of Boswellia carterii. The structures of these diterpenoids were characterized by detailed spectroscopic analysis, and compounds 1-3 were unambiguously confirmed by single-crystal X-ray diffraction experiments. The anti-inflammatory activities of the isolated compounds were evaluated using LPS-induced BV2 cell model and compounds 2-5 showed moderate NO inhibitory effects with IC50 values of 8.84⯱â¯1.02, 9.82⯱â¯1.95, 9.75⯱â¯2.24, and 7.39⯱â¯1.24⯵M, respectively.