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2.
Tissue Antigens ; 76(3): 251-3, 2010 Sep.
Article in English | MEDLINE | ID: mdl-20412464

ABSTRACT

A novel human leukocyte antigen B allele, B*9552, has been identified by sequence-based typing in a donor of Chinese Marrow Donor Program, which has one nucleotide change at position 272 (C-->A) in exon 2 from the closest matching allele B*15010101, resulting in an amino acid substitution from Ser to Tyr at codon 91.


Subject(s)
Alleles , HLA-B Antigens/genetics , Tissue Donors , Amino Acid Substitution , Base Sequence , Bone Marrow Cells , China , HLA-B15 Antigen , Humans , Molecular Sequence Data , Polymerase Chain Reaction , Sequence Analysis, DNA , Sequence Homology, Nucleic Acid
3.
Tissue Antigens ; 74(4): 352-4, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19624612

ABSTRACT

A novel human leukocyte antigen DRB1 allele, DRB1*1219, has been identified in a Chinese leukaemia patient and his family by polymerase chain reaction sequence-based typing, which has one nucleotide change at position 341 (C-->T) in exon 2 from the closest matching allele DRB1*120201, resulting in an amino acid substitution from Ala-->Val at codon 85.


Subject(s)
HLA-DR Antigens/genetics , Leukemia/genetics , Leukemia/pathology , Sequence Analysis, DNA , Alleles , Amino Acid Sequence , Amino Acid Substitution , Base Sequence , China , HLA-DR Antigens/blood , HLA-DRB1 Chains , Humans , Leukemia/blood , Molecular Sequence Data , Polymerase Chain Reaction , Sequence Homology, Amino Acid , Sequence Homology, Nucleic Acid , Siblings
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