1.
Crit Rev Immunol
; 37(1): 39-58, 2017.
Article
in English
| MEDLINE
| ID: mdl-29431078
ABSTRACT
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease linked to profound defects in the function and phenotype of T lymphocytes. Here, we describe abnormal signaling pathways that have been documented in T cells from patients with SLE and discuss how they impact gene expression and immune function, in order to understand how they contribute to disease development and progression.