ABSTRACT
INTRODUCTION: The effectiveness of the Enhanced Recovery After Surgery (ERAS) protocols in gastric cancer surgery remains controversial. METHODS: Multicentre prospective cohort study of adult patients undergoing surgery for gastric cancer. Adherence with 22 individual components of ERAS pathways were assessed in all patients, regardless of whether they were treated in a self-designed ERAS centre. Each centre had a three-month recruitment period between October 2019 and September 2020. The primary outcome was moderate-to-severe postoperative complications within 30 days after surgery. Secondary outcomes were overall postoperative complications, adherence to the ERAS pathway, 30 day-mortality and hospital length of stay (LOS). RESULTS: A total of 743 patients in 72 Spanish hospitals were included, 211 of them (28.4 %) from self-declared ERAS centres. A total of 245 patients (33 %) experienced postoperative complications, graded as moderate-to-severe complications in 172 patients (23.1 %). There were no differences in the incidence of moderate-to-severe complications (22.3% vs. 23.5%; OR, 0.92 (95% CI, 0.59 to 1.41); P = 0.068), or overall postoperative complications between the self-declared ERAS and non-ERAS groups (33.6% vs. 32.7%; OR, 1.05 (95 % CI, 0.70 to 1.56); P = 0.825). The overall rate of adherence to the ERAS pathway was 52% [IQR 45 to 60]. There were no differences in postoperative outcomes between higher (Q1, > 60 %) and lower (Q4, ≤ 45 %) ERAS adherence quartiles. CONCLUSIONS: Neither the partial application of perioperative ERAS measures nor treatment in self-designated ERAS centres improved postoperative outcomes in patients undergoing gastric surgery for cancer. TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT03865810.
Subject(s)
Enhanced Recovery After Surgery , Stomach Neoplasms , Adult , Humans , Perioperative Care , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Prospective Studies , Stomach Neoplasms/surgery , Stomach Neoplasms/complicationsABSTRACT
La cirugía endoscópica transluminal a través de orificios naturales (NOTES, del inglés Natural Orifice Translumenal Endoscopic Surgery), engloba un conjunto de nuevas vías de abordaje endoscópico de la cavidad abdominal, con ventajas potenciales sobre la cirugía laparoscópica convencional. Se fundamenta en la posibilidad de realizar técnicas quirúrgicas intraperitoneales mediante la entrada en la cavidad peritoneal a través de los orificios naturales perforando el órgano que permite la entrada directa a dicha cavidad (estómago, vagina, recto, vejiga). Posteriormente se ha postulado la posibilidad de este mismo acceso para acceder al retroperitoneo y al mediastino. A continuación se comenta como se ha desarrollado la técnica y cómo ha sido la aplicación en nuestro país, intentado dar una visión general sobre los riesgos y beneficios de la NOTES y las necesidades básicas para poder iniciarse en esta nueva cirugía (AU)
Natural orifice transluminal endoscopic surgery (NOTES), involves a group of new endoscopic approaches to the abdominal cavity, with potential advantages over conventional laparoscopic surgery. It is based on the possibility of performing intra-peritoneal surgical techniques through natural orifices by entering the peritoneal cavity through natural orifices perforating the organ that allows direct access to that cavity (stomach, vagina, rectum, bladder). The possibility of using this same route to access the retroperitoneum and mediastinum has subsequently been postulated. Comments are made on how the technique has been developed, as well as how it has been applied in our country, attempting to give a general view on the risks and benefits of NOTES and the basic requirements to be able to start in this new surgery (AU)
Subject(s)
Humans , History, 21st Century , Natural Orifice Endoscopic Surgery/history , Natural Orifice Endoscopic Surgery/methods , Risk Factors , SpainABSTRACT
Natural orifice transluminal endoscopic surgery (NOTES), involves a group of new endoscopic approaches to the abdominal cavity, with potential advantages over conventional laparoscopic surgery. It is based on the possibility of performing intra-peritoneal surgical techniques through natural orifices by entering the peritoneal cavity through natural orifices perforating the organ that allows direct access to that cavity (stomach, vagina, rectum, bladder). The possibility of using this same route to access the retroperitoneum and mediastinum has subsequently been postulated. Comments are made on how the technique has been developed, as well as how it has been applied in our country, attempting to give a general view on the risks and benefits of NOTES and the basic requirements to be able to start in this new surgery.
Subject(s)
Natural Orifice Endoscopic Surgery/history , History, 21st Century , Humans , Natural Orifice Endoscopic Surgery/methods , Risk Factors , SpainABSTRACT
The aim of this study was to describe a new technique to prevent the development of incisional hernias in trocar sites. Between March and June 2006, a pilot study was conducted to determine the feasibility of the safe port plug technique using the Bioabsorbable Hernia Plug to prevent incisional hernia in trocar sites. The device was implanted in the umbilical trocar site (10-11 mm) of 17 patients undergoing laparoscopic surgery during the study period. The mean follow-up of patients was 14.6 months. Implantation of the Bioabsorbable Hernia Plug device by the safe port plug technique was possible in all cases. No patient presented complications in the follow-up. Our preliminary experience suggests that this technique is simple and feasible, and we hypothesized that this technique could be superior to conventional fascial closure: a hypothesis that must be proven in a randomized prospective trial that is currently in progress.
