ABSTRACT
Introduction We aimed to analyse health care services for adolescents and young adults (AYA) with sarcomas in Spain. Methods A survey was sent to all Spanish cancer centres, including questions about demographic, facilities, and treatment strategies for AYAs with sarcomas in the last 2 years. Results Thirty-five units participated in the survey, 17 paediatric and 15 adult units. There were three specialized AYA units. First line regimen varied depending on whether the treating unit was paediatric or not, for osteosarcomas, rhabdomyosarcomas, and non-rhabdomyosarcomas. By contrast, 91.4% of Ewing sarcomas were treated according to EE2012. In the relapse setting, differences between units were higher in all tumours. Additionally, 48% of the units reported not having trials for this population. Conclusion There are major differences in the treatment of AYAs with sarcomas between adult and paediatric units. Enormous efforts are needed to homogenize treatments and increase the access to innovation. (AU)
Subject(s)
Humans , Adolescent , Young Adult , Health Care Surveys , Bone Neoplasms/epidemiology , Bone Neoplasms/therapy , Osteosarcoma/epidemiology , Osteosarcoma/therapy , Neoplasm Recurrence, Local , SpainABSTRACT
INTRODUCTION: We aimed to analyse health care services for adolescents and young adults (AYA) with sarcomas in Spain. METHODS: A survey was sent to all Spanish cancer centres, including questions about demographic, facilities, and treatment strategies for AYAs with sarcomas in the last 2 years. RESULTS: Thirty-five units participated in the survey, 17 paediatric and 15 adult units. There were three specialized AYA units. First line regimen varied depending on whether the treating unit was paediatric or not, for osteosarcomas, rhabdomyosarcomas, and non-rhabdomyosarcomas. By contrast, 91.4% of Ewing sarcomas were treated according to EE2012. In the relapse setting, differences between units were higher in all tumours. Additionally, 48% of the units reported not having trials for this population. CONCLUSION: There are major differences in the treatment of AYAs with sarcomas between adult and paediatric units. Enormous efforts are needed to homogenize treatments and increase the access to innovation.
Subject(s)
Bone Neoplasms , Neoplasms , Osteosarcoma , Sarcoma , Soft Tissue Neoplasms , Adolescent , Bone Neoplasms/epidemiology , Bone Neoplasms/therapy , Child , Humans , Neoplasm Recurrence, Local , Neoplasms/epidemiology , Osteosarcoma/therapy , Sarcoma/therapy , Spain , Young AdultABSTRACT
Hasta el 5% de los tumores colorrectales diagnosticados tiene una causa hereditaria. Este tipo de tumores suele presentarse en pacientes más jóvenes y se pueden asociar a otros tumores extracolónicos. El conocimiento de los principales síndromes hereditarios permitirá un adecuado manejo de estos pacientes, incluyendo aspectos como el consejo genético, el diagnóstico precoz y la cirugía preventiva (AU)
Up to 5% of all diagnosed colorectal cancers has a hereditary cuase. Colon cancer arise in younger individuals, and extracolonic tumors are also frequent. A precise understanding of main syndromes will allow the proper managment of these patients, including genetic counselling, screening and prophylactic surgery (AU)
Subject(s)
Humans , Colonic Neoplasms/genetics , Colorectal Neoplasms, Hereditary Nonpolyposis/genetics , Microsatellite Instability , Adenomatous Polyposis Coli/genetics , Genetic Markers , Genetic Predisposition to DiseaseABSTRACT
Up to 5% of all diagnosed colorectal cancers has a hereditary cuase. Colon cancer arise in younger individuals, and extracolonic tumors are also frequent. A precise understanding of main syndromes will allow the proper management of these patients, including genetic counselling, screening and prophylactic surgery.
