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1.
Eur Geriatr Med ; 2024 Mar 21.
Article in English | MEDLINE | ID: mdl-38512605

ABSTRACT

PURPOSE: Previous studies have shown an association between chronic pain and the occurrence of falls in community-dwelling older adults; however, the association between chronic pain and fall-related injuries in older adults with disabilities is unclear. This study aimed to determine the association between chronic pain and fall-related injuries in older adults with disabilities. METHODS: This 24-month prospective cohort study included older adults aged 65 years or older using Japanese long-term care insurance services. Chronic pain, defined as "pain that has persisted for more than three months to date," was assessed using a face-to-face questionnaire. Fall-related injuries, defined as "injuries requiring hospitalization or outpatient treatment due to a fall," were assessed using a fall calendar. Data were analyzed using a Cox proportional hazards model, with fall-related injury as the dependent variable, chronic pain as the independent variable, and confounders as covariates. RESULTS: Among 133 included participants, 15 experienced fall-related injuries. After adjusting for age and sex as covariates, chronic pain was significantly associated with fall-related injuries (hazard ratio: 5.487, 95% confidence interval: 1.211-24.853, p = 0.027). CONCLUSIONS: Chronic pain was associated with fall-related injuries in older adults with disabilities. In this population, a greater focus should be placed on treating chronic pain to reduce the occurrence of falls.

3.
Article in English | MEDLINE | ID: mdl-37297643

ABSTRACT

(1) Background: This prospective study aimed to identify predictors of falls and fall-related fractures in community-dwelling older people with pain; (2) Methods: Participants comprised 389 community-dwelling older people aged 70+ years who had musculoskeletal pain in the neck, back, hip, leg/knee and/or feet. Demographic, anthropometric, balance, mobility, cognitive function, psychological status and physical activity level measures were obtained at baseline. Falls were monitored with monthly falls calendars for 12 months. Logistic regression analyses were performed to identify predictors of falls and fall-related fractures during a 12-month follow-up; (3) Results: Of the 389 participants, 175 (45.0%) and 20 (5.1%) reported falls and fall-related fractures during the 12-month follow-up, respectively. Greater postural sway on foam, more depressive symptoms and lower physical activity levels at baseline were associated with falls during the 12-month follow-up. Slower walking speed at baseline was associated with fall-related fractures during the 12-month follow-up. These associations remained significant after adjusting for age, sex, body mass index, comorbidities and medication use; (4) Conclusions: This study suggests poor balance, low mood and a less active lifestyle are predictors of falls, and slower walking speed predicts fall-related fractures among community-dwelling older people with pain.


Subject(s)
Fractures, Bone , Musculoskeletal Pain , Humans , Aged , Prospective Studies , Fractures, Bone/epidemiology , Fractures, Bone/etiology , Risk Factors , Independent Living , Postural Balance
4.
Pain Res Manag ; 2023: 1383897, 2023.
Article in English | MEDLINE | ID: mdl-36814427

ABSTRACT

This study aimed to investigate the effect of a rehabilitation program combined with pain management targeting pain perception and activity avoidance on multifaceted outcomes in older patients with acute vertebral compression fractures (VCFs). We randomised 65 older adults with acute VCFs to either an intervention group (n = 32), involving usual rehabilitation combined with pain management that targeted pain perception and activity avoidance, or a control group (n = 33), involving only usual rehabilitation. The usual rehabilitation was initiated immediately after admission. All patients were treated conservatively. Pain management aimed to improve the patients' daily behaviour by increasing their daily activities despite pain, rather than by focusing on eliminating the pain. Pain intensity and psychological statuses such as depression, pain catastrophising, and physical activity levels were assessed on admission. Two weeks postadmission and at discharge, physical performance measures were assessed along with the above-given measurements. A significant main effect of the group was observed for the intensity of lower back pain, favouring the intervention group (F = 5.135, p = 0.027). At discharge, it was significantly better in the intervention group than in the control group (p = 0.011). A time-by-group interaction emerged for magnification of the pain catastrophising scale (p = 0.012), physical activity levels (p < 0.001), and six-minute walking distance (p = 0.006), all favouring the intervention group. Rehabilitation programs combined with pain management targeting pain perception and activity avoidance could be an effective conservative treatment for older patients with acute VCFs.


Subject(s)
Fractures, Compression , Spinal Fractures , Humans , Aged , Pain Management , Pain , Pain Perception
5.
Pain Med ; 24(5): 507-514, 2023 05 02.
Article in English | MEDLINE | ID: mdl-36322001

ABSTRACT

OBJECTIVE: To examine whether compared with a program without increased physical activity, an intervention program with increased physical activity can prevent the development of musculoskeletal pain in community-dwelling older adults. DESIGN: Randomized controlled trial. SETTING: Japanese community. SUBJECTS: Seventy-nine older adults without musculoskeletal pain were randomized into two groups: an intervention group (n = 40) that engaged in increased physical activity and an exercise class and a control group (n = 39) that participated only in the exercise class. METHODS: The exercise class consisted of weekly 60-min sessions over 24 weeks. The program to increase physical activity required the participants to record their daily step counts using pedometers. The primary outcome was the development of musculoskeletal pain, and secondary outcomes were physical function, psychological status, cognitive function, and physical activity levels. RESULTS: Twenty-four weeks after the intervention, the intervention group had a significantly lower prevalence of musculoskeletal pain (12.8%) than the control group (32.4%; P = .040). A time-by-group interaction emerged for cognitive function (P = .01) and physical activity levels (P < .001), both of which favored the intervention group. The intervention group also showed greater improvement in psychological status 24 weeks after the intervention than the control group (P = .018). CONCLUSIONS: The intervention program with increased physical activity prevented the development of musculoskeletal pain and improved cognitive function, physical activity levels, and psychological status more effectively than the program without increased physical activity. Our intervention program may be an effective pain prevention approach for older adults. TRIAL REGISTRATION: UMIN000032768; registered on June 1, 2018.


Subject(s)
Independent Living , Musculoskeletal Pain , Humans , Aged , Exercise , Counseling , Cognition , Exercise Therapy
6.
Physiother Theory Pract ; : 1-9, 2022 Nov 06.
Article in English | MEDLINE | ID: mdl-36335438

ABSTRACT

BACKGROUND: The relationship between chronic pain and the occurrence of falls in healthy older adults has been clarified in previous studies, but its relationship in older adults with disabilities has not. OBJECTIVE: This study aimed to determine whether chronic pain is related to the occurrence of falls in older adults with disabilities. METHODS: The participants were 101 older adults above 65 years old who used long-term care insurance services in Japan. Of these, 30 were fallers and 71 were non-fallers. Chronic pain, defined as pain lasting more than three months, was assessed using questionnaires, and the falls' occurrence was followed up for six months using a fall calendar. Logistic regression analysis was used to analyze the data, with falls as the dependent variable, chronic pain as the independent variable, and age, sex, body mass index, number of drugs, sleep disorders, and depression as covariates. RESULTS: After adjusting for covariates, chronic pain significantly influenced the occurrence of falls (odds ratio: 3.168, 95% confidence interval: 1.057-9.495, p = .04). CONCLUSION: Chronic pain was related to the occurrence of falls in older adults with disabilities. There is a need to focus on chronic pain presence in falls' prevention among older adults with disabilities.

7.
J Back Musculoskelet Rehabil ; 35(5): 1125-1133, 2022.
Article in English | MEDLINE | ID: mdl-35213346

ABSTRACT

BACKGROUND: Research on the multi-faceted characteristics of persistent severe acute lower back pain (LBP) resulting from acute vertebral compression fractures (VCFs) is lacking. OBJECTIVE: To investigate the psychological and functional status of older patients with persistent severe acute LBP after conservative treatment of VCFs. METHODS: This prospective study included women aged 50 years and older who had acute VCFs and were admitted to the hospital. Pain intensity, depression, pain catastrophizing, activities of daily living (ADL), muscle strength, and vertebral deformity were assessed on admission. At 2 and 4 weeks post-admission, physical performance tests were performed along with the above measures. RESULTS: We divided 131 participants into severe (n= 64) and mild (n= 67) groups according to their pain intensity at 4 weeks. Compared to the mild group, the severe group showed significantly higher levels of depression and catastrophizing, with significantly poorer muscle strength and endurance. There were no significant differences in ADL and vertebral deformities between the two groups. CONCLUSIONS: Our results suggest that older patients with persistent severe acute LBP resulting from VCFs tend to be depressed and pain catastrophizing. Furthermore, persistent severe acute LBP negatively impacts endurance and muscle strength but not ADL.


Subject(s)
Acute Pain , Fractures, Compression , Low Back Pain , Spinal Fractures , Activities of Daily Living , Aged , Catastrophization , Depression , Female , Humans , Middle Aged , Prospective Studies , Spinal Fractures/complications
8.
Arch Gerontol Geriatr ; 99: 104582, 2022.
Article in English | MEDLINE | ID: mdl-34847515

ABSTRACT

AIM: Previous studies have highlighted the causation between chronic pain and falls in the elderly, but the mediator variables between chronic pain and falls in the frail elderly have not been identified. The purpose of this study was to identify the mediator variable of chronic pain and falls. METHODS: This study is a prospective cohort study. Participants were 116 frail elderly individuals living in a community. Chronic pain (pain lasting more than 3 months) was assessed using a questionnaire, and the occurrence of falls was tracked using a falls calendar. Using logistic regression, a model was created with falls as the dependent variable and chronic pain and confounders as independent variables. The mediation analysis was conducted with chronic pain as the independent variable, falls as the dependent variable, and factors that showed significant differences between the chronic pain group and the non-chronic pain group as candidate mediators. RESULTS: Even after adjusting for covariates, chronic pain significantly influenced the occurrence of falls (odds ratio: 3.004, 95% CI [1.226, 7.363], p=0.016). The results of mediation analysis showed a significant direct effect between chronic pain and falls, and a significant indirect effect (partial mediation) of sleep disorders on the relationship between chronic pain and falls. CONCLUSIONS: Chronic pain in frail elderly mediates sleep disorders and influences falls. It is suggested that interventions for chronic pain and sleep disorders should focus on preventing falls in the frail elderly.


Subject(s)
Chronic Pain , Sleep Wake Disorders , Aged , Chronic Pain/epidemiology , Frail Elderly , Humans , Prospective Studies , Sleep Wake Disorders/complications , Sleep Wake Disorders/epidemiology
9.
J Knee Surg ; 35(8): 922-931, 2022 Jul.
Article in English | MEDLINE | ID: mdl-33241542

ABSTRACT

Severe acute pain after total knee arthroplasty (TKA) may cause delay in muscle strength and functional recovery, and it is a risk factor for chronic postoperative pain. Although pharmacological approaches are the typical firstline to treat acute pain; recently, nonpharmacological approaches such as exercise have been increasingly applied. The purpose of this investigation was to evaluate the effects of a rehabilitation program involving isometric quadriceps exercise with auditory and visual feedback to improve the short-term outcome after TKA. Sixty-two patients, planning a primary unilateral TKA, were randomly assigned to either an intervention group (n = 31) involving isometric quadriceps exercise with auditory and visual feedback in usual rehabilitation after TKA or a control group (n = 31) involving a standardized program for TKA. Patients in the intervention group performed the isometric quadriceps muscle exercise using the Quadriceps Training Machine from 2 to 14 days after TKA instead of the traditional quadriceps sets. Pain intensity, isometric knee extension strength, range of motion, timed up and go test (TUG), 10-m gait speed, 6-minute walking distance, the Western Ontario and McMaster University Osteoarthritis index (WOMAC), the hospital anxiety and depression scale, and the pain catastrophizing scale were assessed before TKA (baseline) and 1 to 3 weeks after TKA. Pain intensity significantly decreased in the intervention group than in the control group at 1 (p = 0.005), 2 (p = 0.002), and 3 (p = 0.010) weeks after TKA. Greater improvements in TUG (p = 0.036), 10-m gait speed (p = 0.047), WOMAC total score (p = 0.017), pain (p = 0.010), and function (p = 0.028) 3 weeks after TKA were observed in the intervention group. These results suggest that isometric quadriceps exercises with auditory and visual feedback provided early knee pain relief, possibly leading to better improvements in physical performance, and patient's perception of physical function in the early stages of postoperative TKA. Further studies should investigate whether this short-term effect is sustainable.


Subject(s)
Acute Pain , Arthroplasty, Replacement, Knee , Osteoarthritis, Knee , Acute Pain/surgery , Arthroplasty, Replacement, Knee/rehabilitation , Feedback, Sensory , Humans , Muscle Strength/physiology , Osteoarthritis, Knee/surgery , Postural Balance , Quadriceps Muscle/surgery , Range of Motion, Articular/physiology , Recovery of Function/physiology , Time and Motion Studies , Treatment Outcome
10.
Medicine (Baltimore) ; 100(41): e27533, 2021 Oct 15.
Article in English | MEDLINE | ID: mdl-34731148

ABSTRACT

ABSTRACT: Understanding the relationship between pain and physical activity (PA) levels is beneficial for maintaining good health status. However, the impact of pain on changes in PA during the coronavirus disease 2019 (COVID-19) pandemic is unknown. The purpose of this study was to examine whether PA levels pre-, during, and post-COVID-19 state of emergency differ between Japanese adults who had pain after the COVID-19 state of emergency and those who did not.Data were collected from a cross-sectional online survey conducted between October 19 and 28, 2020. The analytic sample consisted of 1967 Japanese adults aged ≥40 years who completed the online survey. Participants completed questionnaires on the presence of pain and duration of PA, defined as the total PA time per week based on activity frequency and time. Participants were asked to report their PA at 3 time points: October 2019 (before the COVID-19 pandemic), April 2020 (during the COVID-19 state of emergency), and October 2020 (after the COVID-19 state of emergency).Among participants aged ≥60 years who reported pain in October 2020, the total PA time was significantly lower than participants who did not report having pain. Furthermore, the total PA time in April 2020 was significantly lower than that in October 2019; however, no significant difference in total PA time was observed between April and October 2020. Among participants aged 40 to 59 years, no significant differences were observed in total PA times at the 3 time points between those with and without pain. In addition, the total PA time in October 2020 significantly increased compared to that in April 2020, although it significantly decreased in April 2020 compared to October 2019.This study suggests that older adults with pain have lower PA levels after the COVID-19 state of emergency.


Subject(s)
Exercise , Pain/epidemiology , Adult , Aged , Aged, 80 and over , COVID-19/epidemiology , Cross-Sectional Studies , Female , Humans , Japan/epidemiology , Male , Middle Aged , Pandemics , SARS-CoV-2 , Surveys and Questionnaires
11.
Geriatr Gerontol Int ; 21(6): 519-524, 2021 Jun.
Article in English | MEDLINE | ID: mdl-33890382

ABSTRACT

AIM: The aim of this prospective cohort study was to identify the predictors of the development and persistence of musculoskeletal pain (MSKP) in older people. METHODS: Participants comprised 431 community-dwelling older people aged 70+ years. Demographic, anthropometric, balance, mobility, cognitive function, psychological status and physical activity level measures were obtained at baseline. Participants were asked about the presence of MSKP in the neck/back, hip, knee/leg and/or feet at baseline and two-year follow-up. Logistic regression analyses were performed to identify predictors of the development and persistence of MSKP at two-year follow-up. RESULTS: Of 179 participants who reported no MSKP at baseline, 84 (46.9%) reported MSKP at two-year follow-up, which was associated with a higher body mass index (odds ratio (OR) 1.10, 95% confidence interval (CI) 1.02-1.18), more reported depressive symptoms (OR 1.30, 95% CI 1.05-1.61) and lower physical activity levels (OR 0.92, 95% CI 0.84-1.00) at baseline. Of 252 participants who reported MSKP at baseline, 202 (80.2%) reported MSKP at follow-up, which was associated with a slower 6-m walking time (OR 1.27, 95% CI 1.08-1.49) and more reported depressive symptoms (OR 1.39, 95% CI 1.09-1.78). These associations remained significant after adjusting for age, sex, comorbidities and medication use. CONCLUSIONS: This study suggests that higher body mass index, more depressive symptoms and less physical activity are predictors of developing MSKP, whereas slow gait speed and depressive symptoms are predictors of the persistence of MSKP among older people. The results highlight the importance of weight control, strategies to improve mental wellbeing and an active lifestyle for pain management among older people. Geriatr Gerontol Int 2021; 21: 519-524.


Subject(s)
Independent Living , Musculoskeletal Pain , Aged , Humans , Longitudinal Studies , Musculoskeletal Pain/diagnosis , Musculoskeletal Pain/epidemiology , Prospective Studies , Walking
12.
Pain Res Manag ; 2020: 8814290, 2020.
Article in English | MEDLINE | ID: mdl-33204378

ABSTRACT

Osteoporotic fractures are common among older people, and hip fractures (HF) can be devastating. Surgery is indicated for most cases of HF, and chronic persistent postoperative pain is likely to occur. This study investigated the multifaceted factors related to persistent pain occurring during the acute phase and subacute phase of recovery after HF surgery. We conducted a prospective 8-week study of older HF patients after surgery. We evaluated pain intensity, depression symptoms, the fear of falling, pain catastrophizing, cognition and attention, the ability to perform activities of daily living, and the physical performance at 2 weeks (acute phase) and at 4 weeks (subacute phase) after surgery. Patients were divided into the light group (Verbal Rating Scale (VRS) score ≤1) and severe group (VRS score ≥2) according to pain intensity at 8 weeks (recovery phase) after surgery. Factors affecting persistent postoperative pain during recovery were examined using logistic regression analysis. Seventy-two patients were analyzed: 50 in the light group and 22 in the severe group. In the severe group, pain with movement and Pain Catastrophizing Scale scores were higher than those of the light group at 2 weeks and at 4 weeks after surgery. The regression analysis showed that pain with movement at 2 weeks and at 4 weeks after surgery and pain catastrophizing at 4 weeks after surgery were related to persistent postoperative pain. HF patients may have persistent pain if they continue to experience pain and catastrophize their pain during the acute phase and subacute phase after surgery.


Subject(s)
Catastrophization/diagnosis , Catastrophization/psychology , Hip Fractures/psychology , Hip Fractures/surgery , Pain, Postoperative/diagnosis , Pain, Postoperative/psychology , Accidental Falls , Activities of Daily Living/psychology , Adult , Aged , Aged, 80 and over , Catastrophization/epidemiology , Chronic Pain/diagnosis , Chronic Pain/etiology , Chronic Pain/psychology , Fear/psychology , Female , Hip Fractures/epidemiology , Humans , Japan/epidemiology , Male , Middle Aged , Pain, Postoperative/epidemiology , Prospective Studies
13.
Article in English | MEDLINE | ID: mdl-32660067

ABSTRACT

(1) Background: The present study aimed to examine physical, cognitive and emotional factors affecting falls in community-dwelling older adults with and without pain; (2) Methods: Data from 789 older adults who participated in a community-based health survey were analyzed. Participants completed questionnaires on the presence of pain and previous falls. Muscle weakness (handgrip strength < 26.0 kg for men and < 18.0 kg for women) and low skeletal muscle mass (appendicular skeletal muscle mass index < 7.0 kg/m2 for men and < 5.7 kg/m2 for women) were determined. Mild cognitive impairment (MCI) and depressive symptoms were assessed using the National Center for Geriatrics and Gerontology-Functional Assessment Tool and 15-item geriatric depression scale (GDS-15), respectively; (3) Results: In participants with pain, MCI and GDS-15 were associated with previous falls after adjusting for age, sex, education and medication use. In participants without pain, muscle weakness and low skeletal muscle mass were associated with previous falls when adjusting for the above covariates; (4) Conclusions: Falls in participants with pain were associated with cognitive and emotional factors, whereas falls in those without pain were associated with physical factors. Fall prevention interventions for older adults with pain may require tailored strategies to address cognitive and emotional factors.


Subject(s)
Accidental Falls , Cognition , Independent Living , Pain , Aged , Female , Geriatric Assessment , Hand Strength , Humans , Knee , Low Back Pain , Male , Pain/complications , Risk Factors
14.
Age Ageing ; 49(6): 982-988, 2020 10 23.
Article in English | MEDLINE | ID: mdl-32417879

ABSTRACT

BACKGROUND: pain is associated with increased postural sway and falls in older adults. However, the impact of pain on reactive balance induced by postural perturbations and how this might predispose older adults to falls is not known. OBJECTIVE: to investigate whether any pain, back/neck pain and lower limb pain are associated with poor reactive balance and prospective fall outcomes in older adults. DESIGN: 12-month prospective cohort study. SETTING: community. SUBJECTS: 242 community-dwelling older adults aged 70+ years. METHODS: participants completed a questionnaire on the presence of pain and underwent force-controlled waist-pull postural perturbations while standing. Force thresholds for stepping, step initiation time, step velocity and step length were quantified. Falls were monitored with monthly falls calendars for 12-months. RESULTS: participants with lower limb pain had significantly lower force thresholds for stepping. Those with any pain or pain in the back/neck had longer step initiation time, slower step velocity and shorter step length. The three pain measures (any pain, back/neck pain, lower limb pain) were significantly associated with multiple falls when adjusted for age, sex, body mass index, use of polypharmacy, strength and walking speed. In mediation analyses, there was a significant indirect effect of reactive balance for the relationship between back/neck pain and falls with fractures. CONCLUSIONS: older people with pain have impaired reactive balance and an increased risk of falls. Reactive balance partially mediated the association between pain and fall-related fractures. Further research is required to confirm the findings of this study.


Subject(s)
Independent Living , Postural Balance , Aged , Humans , Neck Pain , Prospective Studies
15.
J Am Med Dir Assoc ; 21(5): 597-603.e8, 2020 05.
Article in English | MEDLINE | ID: mdl-32334772

ABSTRACT

OBJECTIVES: Pain is a risk factor for falls in older adults, but the mechanisms are not well understood, limiting our ability to implement effective preventive strategies. The aim of this study was to systematically review and synthesize the literature that has examined the impact of pain on static, dynamic, multicomponent, and reactive balance in community-dwelling older adults. DESIGN: Systematic review and meta-analysis. SETTING AND PARTICIPANTS: Studies from inception to March 2019 were identified from electronic databases (MEDLINE, EMBASE, PsycINFO, CINAHL), contact with the primary authors, and reference lists of included articles. METHODS: Cross-sectional and case-control studies that compared objective balance measures between older (minimum age 60 years) adults with and without pain were included. RESULTS: Thirty-nine eligible studies (n = 17,626) were identified. All balance modalities (static, dynamic, multicomponent, and reactive) were significantly poorer in participants with pain compared to those without pain. Subgroup analyses revealed that chronic pain (pain persisting ≥3 months) impaired balance more than pain of unspecified duration. The effects of pain at specific sites (neck, lower back, hip, knee, and foot) on balance were not significantly different. CONCLUSIONS AND IMPLICATIONS: Pain is associated with poor static, dynamic, multicomponent, and reactive balance in community-dwelling older adults. Pain in the neck, lower back, hip, knee, and foot all contribute to poor balance, and this is even more pronounced for chronic pain. Comprehensive balance and pain characteristic assessments may reveal mechanisms underlying the contribution of pain to instability and increased fall risk in older people.


Subject(s)
Chronic Pain , Independent Living , Aged , Chronic Pain/epidemiology , Cross-Sectional Studies , Humans , Middle Aged , Postural Balance , Risk Factors
16.
Geriatr Gerontol Int ; 19(11): 1153-1156, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31646711

ABSTRACT

AIM: The present study aimed to determine whether measures of chronic pain are associated with social frailty in community-dwelling older adults. METHODS: Participants comprised 248 older adults who enrolled for community-based exercise classes. Chronic pain was defined as the presence of significant pain-related symptoms within the past month that had continued for at least 6 months. Social frailty was defined as positive responses to two of the following five questions (going out less frequently, rarely visiting friends, feeling unhelpful to friends or family, living alone and not talking with someone every day). Physical function was assessed using the Chair Stand and Timed Up and Go tests. RESULTS: A total of 55 participants (22.2%) met the criteria for social frailty. A total of 28 socially frail participants (50.9%) and 56 of the socially integrated participants (29.0%) reported chronic pain. The presence of chronic pain was significantly associated with social frailty after adjusting for age, sex and physical function measures (odds ratio 2.13, 95% confidence interval 1.01-4.48). Chronic pain was also significantly associated with three social frailty items: going out less frequently, rarely visiting friends and feeling unhelpful to friends or family. CONCLUSIONS: Chronic pain was independently associated with social frailty in community-dwelling older adults. Simple assessments of chronic pain and subsequent pain management interventions might be beneficial for older people with social frailty. Geriatr Gerontol Int 2019; 19: 1153-1156.


Subject(s)
Chronic Pain/etiology , Frail Elderly/psychology , Social Participation , Sociological Factors , Aged , Aged, 80 and over , Chronic Pain/epidemiology , Cross-Sectional Studies , Female , Humans , Independent Living , Male
17.
Eur J Cancer Care (Engl) ; 28(2): e12956, 2019 Mar.
Article in English | MEDLINE | ID: mdl-30357948

ABSTRACT

OBJECTIVE: In this study, we investigated the muscle function of patients with haematological malignancy and healthy controls and examined the effect of cachexia on muscle function. METHODS: Seventy-one patients with haematological malignancy, hospitalised for chemotherapy, and 71 healthy controls underwent examination of skeletal muscle mass (SMM; total body and upper and lower limbs), handgrip strength and isometric knee extensor strength. Patients with haematological malignancy were divided into three groups based on Glasgow Prognostic Score: non-cachexia (n = 31), pre-cachexia (n = 23) and cachexia (n = 17) groups. The evaluation items were compared among the groups. RESULTS: Patients with haematological malignancy had lower SMM of the total body and lower limbs, handgrip strength and isometric knee extensor strength than healthy controls. There was no significant difference in SMM of the upper limbs among the groups. When classifying patients with haematological malignancy according to GPS, there was no significant difference among the three groups for any of the evaluation items. CONCLUSIONS: In patients with haematological malignancy, although significant muscle wasting and weakness were observed in the lower limbs, the effect of cachexia was minimal. The reduction in muscle function involved disuse syndrome, which accompanied a decline in physical activity.


Subject(s)
Cachexia/physiopathology , Hematologic Neoplasms/physiopathology , Muscle, Skeletal/physiology , Aged , Case-Control Studies , Cross-Sectional Studies , Female , Hand Strength/physiology , Humans , Isometric Contraction/physiology , Knee Joint/physiology , Male , Muscle Strength/physiology , Prognosis
18.
Pain Res Manag ; 2018: 2132039, 2018.
Article in English | MEDLINE | ID: mdl-29849840

ABSTRACT

Objective: With the aim of developing a chronic pain prevention program, this randomized controlled trial examined whether exercise training combined with increased physical activity more effectively improves pain and physical activity than exercise training alone in community-dwelling older adults without chronic pain. Methods: We randomized 76 older adults without chronic pain into an intervention group (n=38) involving exercise training combined with increased physical activity and a control group (n=38) involving exercise training alone. The exercise training comprised weekly 60-min sessions for 12 weeks. The program to increase physical activity required participants to record their daily step counts using pedometers. Pain intensity, total number of pain sites, and physical activity were assessed before and 12 weeks after the intervention. Results: A time-by-group interaction was found for physical activity, with the intervention group showing significant improvement (p < 0.05). The intervention group also showed greater improvement in pain intensity and total number of pain sites at 12 weeks after intervention than the control group (p < 0.05). Conclusions: In older adults without chronic pain, exercise training combind with increased physical activity improves key outcome indicators more effectively than exercise training alone. "This trial is registered with UMIN000018503."


Subject(s)
Aging/physiology , Chronic Pain/prevention & control , Exercise Therapy/methods , Exercise/physiology , Independent Living , Aged , Aged, 80 and over , Female , Humans , Male , Psychiatric Status Rating Scales , Retrospective Studies , Treatment Outcome
19.
Nihon Ronen Igakkai Zasshi ; 55(1): 124-130, 2018.
Article in Japanese | MEDLINE | ID: mdl-29503354

ABSTRACT

AIM: Efforts to improve the treatment of frail elderly patients in acute care hospitals are urgently needed because a low physical activity level due to hospitalization is reported to be associated with a risk of disability. The aim of this study was to clarify the characteristics of frail elderly patients in acute care hospitals. METHODS: We assessed 198 elderly patients who were admitted to acute care hospitals. The factors that were evaluated included the presence of frailty, the age, gender, and nutritional status of the patients, and complications that developed during hospitalization. In this study, frailty was evaluated using the Kihon checklist (KCL), and was defined by a total KCL score of ≥7 points. RESULTS: A total of 87 (43.9%) subjects met the definition of frailty and there was a female predominance (63.2%). The nutritional status of the subjects with frailty was significantly worse than that of the non-frail patients. In comparison to the non-frail subjects, the frail subjects were significantly older and the onset of complications during hospitalization was observed significantly more frequently. Moreover, a large number of frail subjects showed low scores on the KCL items related to their social activity, physical and oral functions, and psychological status. CONCLUSION: These findings suggest that efforts to improve the treatment of frail elderly patients in acute care hospitals are important because of the high incidence of frailty. Multifaceted assessments and the promotion of physical activity to prevent the onset of complications during hospitalization may be needed for frail elderly patients in acute care hospitals.


Subject(s)
Frail Elderly , Aged , Aged, 80 and over , Checklist , Female , Hospitalization , Humans
20.
Geriatr Gerontol Int ; 18(7): 1079-1084, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29582534

ABSTRACT

AIM: The present cross-sectional study investigated the relationship between frailty and chronic pain, activities of daily living (ADL), and physical activity in community-dwelling older adults. METHODS: Participants were 379 older adults who attended community-based exercise classes. Outcome measures were frailty as determined by the Kihon Checklist, full pain assessment (including the sensory, emotional and cognitive aspects of pain), ADL and physical activity. These outcomes were evaluated using validated tests and instruments. Assessments were carried out before beginning the exercise classes. Outcome measures were compared for participants with and without frailty. Frailty was defined as a total Kihon Checklist score ≥7, and chronic pain as the presence of related symptoms within the past month that had continued for at least 6 months and corresponded with a numerical rating scale score of at ≥5 at the site of maximum pain. RESULTS: In total, 134 (35.4%) participants met the frailty criteria; 60.4% of this group had chronic pain. The frail group had significantly worse scores for the sensory, emotional and cognitive aspects of pain, ADL and physical activity than the non-frail group (P < 0.05). Logistic regression analysis adjusted for age and sex showed the sensory and emotional aspects of pain were associated with frailty. CONCLUSIONS: For community-dwelling older adults with frailty, chronic pain can negatively influence sensory, emotional and cognitive aspects of pain, leading to a decline in ADL and lower physical activity. Full pain assessment focused on sensory and emotional aspects of pain is important to identify frailty among older adults. Geriatr Gerontol Int 2018; 18: 1079-1084.


Subject(s)
Activities of Daily Living , Chronic Pain/epidemiology , Exercise/physiology , Frailty/epidemiology , Musculoskeletal Pain/epidemiology , Quality of Life , Aged , Aged, 80 and over , Chronic Pain/diagnosis , Chronic Pain/therapy , Cross-Sectional Studies , Female , Frail Elderly , Frailty/physiopathology , Geriatric Assessment , Humans , Independent Living , Japan , Logistic Models , Male , Musculoskeletal Pain/diagnosis , Musculoskeletal Pain/therapy , Pain Management , Sickness Impact Profile , Statistics, Nonparametric
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