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1.
Article in English | MEDLINE | ID: mdl-32878184

ABSTRACT

This study quantified the neck posture and fatigue using the flexion relaxation phenomenon (FRP) and craniovertebral angle (CVA); further, it compared the difference between the level of fatigue and neck posture induced by two types of monitors (regular fixed monitor and moving monitor). Twenty-three male participants were classified into two groups-the low-flexion relaxation ratio (FRR) group and the normal-FRR group, depending on the FRR value. All participants performed a document task for 50 min using both types of monitors. It was found that the FRR values significantly decreased after the documentation task. The CVA analysis showed that the moving monitor's frequency of forward head posture (FHP) was lower than that for the fixed monitor. Overall, the moving monitor worked better than the fixed monitor; this can be interpreted as proof that such monitors can reduce neck fatigue.


Subject(s)
Fatigue , Neck , Posture , Adult , Head , Humans , Male , Range of Motion, Articular
2.
Org Biomol Chem ; 7(23): 4960-4, 2009 Dec 07.
Article in English | MEDLINE | ID: mdl-19907787

ABSTRACT

A convenient method is disclosed for the synthesis of both 3-hydroxyisoquinolines and 2-hydroxy-1,4-naphthoquinones from beta-ketoesters using a one-pot aryne acyl-alkylation/condensation procedure. When performed in conjunction with a one-step method for the synthesis of the beta-ketoester substrates, this method provides a new route to these polyaromatic structures in only two steps from commercially available carboxylic acid starting materials. The utility of this approach is demonstrated in the synthesis of the atropisomeric P,N-ligand, QUINAP.


Subject(s)
Alkynes/chemistry , Isoquinolines/chemical synthesis , Naphthoquinones/chemical synthesis , Alkylation , Esters/chemistry , Isoquinolines/chemistry , Ketones/chemistry , Molecular Structure , Naphthoquinones/chemistry , Stereoisomerism
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