ABSTRACT
BACKGROUND: This study is focused on the opening technique of the cervical vertebrae during laminoplasty which serves to substantially reduce the most severe adverse effects of the simple resection of posterior vertebral elements. This computational study aims to clarify by an optimisation approach what shape and position upon the lamina the groove should have. METHODS: The computational model was developed in the computational software COMSOL Multiphysics 5.6a based on a computer tomography data obtained from the C4 vertebra. For finding the optimal minimum or maximum of a function (surface), optimisation algorithms are developed following the Nelder-Mead algorithm. RESULTS: The reaction-opening force increases with a decreasing groove radius and an increasing position from the vertebra body. The created area increases with a decreasing groove radius and a decreasing position. As the opening happens mostly only above the groove, the opening area increases only in this location. Moreover, the von Mises stress peak value is almost twice as large as in the case of maximization of the opening area, which might result in breaking of the lamina as the thickness of the lamina would be reduced to its minimum. CONCLUSION: The groove radius and position can affect the opening force and the opening area in case of double door laminoplasty. The opening force is highly influenced by the groove position and radius. The best position for placing the groove is in the middle of the lamina and the radius of the groove should be as large as possible.
Subject(s)
Laminoplasty , Algorithms , Biomechanical Phenomena , Cervical Vertebrae/diagnostic imaging , Cervical Vertebrae/surgery , Humans , Laminoplasty/adverse effects , Tomography, X-Ray ComputedABSTRACT
The presented text deals with research into the influence of the printing layers' orientation on crack propagation in an AlSi10Mg material specimen, produced by additive technology, using the Direct Metal Laser Sintering (DMLS) method. It is a method based on sintering and melting layers of powder material using a laser beam. The material specimen is presented as a Compact Tension test specimen and is printed in four different defined orientations (topology) of the printing layers-0°, 45°, 90°, and twice 90°. The normalized specimen is loaded cyclically, where the crack length is measured and recorded, and at the same time, the crack growth rate is determined. The evaluation of the experiment shows an apparent influence of the topology, which is essential especially for possible use in the design and technical preparation of the production of real machine parts in industrial practice. Simultaneously with the measurement results, other influencing factors are listed, especially product postprocessing and the measurement method used. The hypothesis of crack propagation using Computer Aided Engineering/Finite Element Method (CAE/FEM) simulation is also stated here based on the achieved results.
ABSTRACT
BACKGROUND: The expansion of the cervical vertebrae lamina appears to be crucial to related surgical procedures. The dimensions of the groove influence the strain concentration within the lamina of the vertebra and, thus, the potential success or failure of respective surgical procedure. The aim of this computational study is to clarify both the role of the size of the groove with concern to both the open door and the double door laminoplasty techniques. METHODS: Finite element models were created via computer tomography with varying lamina groove dimensions. Displacements were applied to the models at the open side of the vertebral arch and the vertebral body was constrained prior to movement along all the axes. The maximal opening size measured on the inner side of the lamina and the percentage increase in the initial spinal areas were subsequently analyzed. FINDINGS: The elastic strain concentration value was observed for the groove in all cases, while the maximal principal elastic strain concentration value was observed at the opposite side to the groove cut into the lamina, also in all cases. The maximal area increase related to the 4 mm groove accompanied by the preservation of the ventral cortex of the bone. INTERPRETATION: The study suggested three conclusions a) the wider the groove, the greater is the opening potential, b) the maximal opening size following laminoplasty is not dependent on the depth of the bone cut for this type of groove, c) no benefit accrues in terms of the opening size following the cutting of a supplementary groove at the beginning of the lamina.
Subject(s)
Laminoplasty , Cervical Vertebrae/diagnostic imaging , Cervical Vertebrae/surgery , Humans , Retrospective Studies , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
The purpose of the study was to compare the stability of the plate osteosyntheses of intra-articular calcaneal fractures using various types of a sustentacular screw insertions. A geometrical model of a calcaneal fracture was created. The fracture was fixed with a plate and screws with a uniform distribution. The individual models differed regarding the position of the sustentacular screw. The screw was inserted using three different variants: Model A: into the tip of sustentaculum tali, Model B: under the sustentaculum tali, and Model C: into the inferior peripherial rim of the sustentacular fragment. In all three variants, the screw was either locked into the plate via threads or unlocked. The model was loaded with force in the vertical direction. The stiffness of individual models was evaluated using the finite element method, which was expressed as the maximum force (Fmax) that the system was able to transmit and by determining the magnitude and distribution of reduced stress (σred) on the individual parts of the model of a fixed calcaneal fracture. The greatest stiffness of the system was observed in the Model B (Fmax = 335.8 N). The least stiffness was observed in Model C (Fmax = 296.3 N). This model also produced the greatest load on bone tissue was observed (σmaxred = 67.5 MPa). The least load on bone tissue was measured in Model B (σmaxred = 53.7 MPa). The load on the plate was similar in all three models (814.0-820.0 MPa). The analyses suggest that in a plate osteosynthesis of a calcaneal fracture, the insertion of a sustentacular screw under the tip of the sustentaculum tali is acceptable in terms of osteosynthesis stability. This sustentacular screw position reduces the risk of the screw penetrating into the talocalcaneal joint.
Subject(s)
Calcaneus , Fractures, Bone , Biomechanical Phenomena , Bone Plates , Bone Screws , Calcaneus/surgery , Fracture Fixation, Internal , Fractures, Bone/surgery , HumansABSTRACT
Rigid polyurethane (PUR) foam, which has an extensive range of construction, engineering, and healthcare applications, is commonly used in technical practice. PUR foam is a brittle material, and its mechanical material properties are strongly dependent on temperature and strain rate. Our work aimed to create a robust FE model enabling the simulation of PUR foam machining and verify the results of FE simulations using the experiments' results. We created a complex FE model using the Arbitrary Lagrangian-Eulerian (ALE) method. In the developed FE model, a constitutive material model was used in which the dependence of the strain rate, damage initiation, damage propagation, and plastic deformation on temperature was implemented. To verify the FE analyses' results with experimentally measured data, we measured the maximum temperature during PUR foam drilling with different densities (10, 25, and 40 PCF) and at various cutting speeds. The FE models with a constant cutting speed of 500 mm/s and various PUR foam densities led to slightly higher Tmax values, where the differences were 13.1% (10 PCF), 7.0% (25 PCF), and 10.0% (40 PCF). The same situation was observed for the simulation results related to various cutting speeds at a constant PUR foam density of 40 PCF, where the differences were 25.3% (133 mm/s), 10.1% (500 mm/s), and 15.5% (833 mm/s). The presented results show that the ALE method provides a good match with the experimental data and can be used for accurate simulation of rigid PUR foam machining.
ABSTRACT
Rigid polyurethane (PUR) foam is products used as a biomedical material for medical device testing. Thermal stability is a very important parameter for evaluating the feasibility of use for testing surgical instrument load during drilling. This work aimed to perform experimental measurements to determine the dependence of the mechanical properties of a certified PUR on temperature, strain rate and density. Experimental measurements were realised for three types of the PUR samples with different density 10, 25 and 40 pounds per cubic foot. The samples were characterised in terms of their mechanical properties evaluated from tensile and compression tests at temperatures of 25 °C, 90 °C and 155 °C. Furthermore, the structures of the samples were characterised using optical microscope, their thermal properties were characterised by thermogravimetric analysis, and their density and stiffness with the effect of temperature was monitored. The results show that it is optimal not only for mechanical testing but also for testing surgical instruments that generate heat during machining. On the basis of experimental measurements and evaluations of the obtained values, the tested materials are suitable for mechanical testing of medical devices. At the same time, this material is also suitable for testing surgical instruments that generate heat during machining.
ABSTRACT
The aim of our study was to identify potential critical levels of implantation of an osseointegrated prosthesis for above-knee amputees. The implant used was the OPRA system. It was inserted in the femur at four different amputation heights, characterized by their residual limb ratios (0.299, 0.44, 0.58 and 0.73). The stress and strain distribution was evaluated in the bone-implant system during walking, considering a body mass of 100 kg. Considerably high stimulus (11,489 µÎµ) in the tissue near the tip was found at the highest implantation level. All models presented small non-physiologic stress values in the tissue around the implant. The results revealed that the implantation level has a decisive effect on bone-implant performance. Mainly, the analysis indicates adverse biomechanical conditions for implantations in very short residual limbs.
Subject(s)
Amputees , Knee/surgery , Osseointegration , Prosthesis Implantation , Amputation, Surgical , Femur/physiology , Femur/surgery , Humans , Male , Materials Testing , Middle Aged , Weight-BearingABSTRACT
The study was aimed at the clinical and biomechanical analyses of the sliding hip screw breakage with the use of finite element method. We have identified two patients with the sliding screw breakage. In the first patient, the biomechanical analysis revealed the reduced stress values σHMH not exceeding the yield limit or strength limit of the implant. The yield limit was exceeded in second one. Clinical and biomechanical analyses have demonstrated that adherence to technical requirements of the appropriate osteosynthesis implementation is the principal condition of timely healing since it prevents the material failure.
Subject(s)
Bone Screws , Hip Fractures/physiopathology , Prosthesis Failure , Stress, Mechanical , Aged, 80 and over , Biomechanical Phenomena , Female , Hip Fractures/diagnostic imaging , Humans , Male , Materials Testing , Middle Aged , Models, TheoreticalABSTRACT
Ankle fractures are complex injuries with variable prognoses that depend upon many factors. The aim of the treatment is to restore the ankle joint biomechanical stability with maximum range of motion. Most ankle fractures are fibular fractures, which have a typical oblique fracture line in the distal fibula located in the area of the tibiofibular syndesmosis. The aim of this study was to simulate numerically several fixation techniques of the distal fibular fractures, evaluate their stability, determine their impact on surrounding tissue load, and correlate the results to clinical treatment experience. The following three models of fibular fracture fixation were used: (a) plate fixation with three screws attached above/below and lag screws, (b) plate fixation with two screws attached above/below and lag screws, and (c) three lag screws only. All three fracture fixation models were analyzed according to their use in both healthy physiological bone and osteoporotic bone tissue. Based on the results of Finite Element Analysis for these simulations, we found that the most appropriate fixation method for Weber-B1 fibular fractures was an unlocked plate fixation using six screws and lag screws, both in patients with physiological and osteoporotic bone tissue. Conversely, the least appropriate fixation method was an unlocked plate fixation with four screws and lag screws. Although this fixation method reduces the stress on patients during surgery, it greatly increased loading on the bone and, thus, the risk of fixation failure. The final fixation model with three lag screws only was found to be appropriate only for very limited indications.
Subject(s)
Ankle Fractures/physiopathology , Ankle Fractures/surgery , Bone Plates , Fibula/injuries , Fibula/physiopathology , Fracture Fixation, Internal/instrumentation , Models, Biological , Compressive Strength , Computer Simulation , Equipment Failure Analysis , Fibula/surgery , Fracture Fixation, Internal/methods , Friction , Humans , Prosthesis Design , Stress, Mechanical , Tensile Strength , Treatment Outcome , Weight-BearingABSTRACT
The temporomandibular (TM) joint is one of the most active joints in the human body, and any defect in this joint has a significant impact on the quality of life. The objective of this study was to analyze changes in the force ratio after TM joint replacement on contralateral TM joint loading. Implantation of an artificial TM joint often requires removal of 3 of the 4 masticatory muscles (activators). In order to perform true loading of the TM joint, loading during mastication was investigated. Input kinematic variables and mastication force were experimentally examined. The inverse dynamics approach and static optimization technique were used for solution of the redundant mechanism. Muscle forces, and reactions in the TM joint were calculated. We modified the model for several different tasks. The m. temporalis and m. masseter were removed individually and together and the forces of mastication on the TM joint were calculated for each variation. To evaluate the results, a parametric numerical FE analysis was created to compare the magnitude of the TM joint loading during the bite process for four different muscle resections. The results show an influence relative to the extent of muscle resection on contralateral TM joint loading in a total TM joint replacement. The biggest increase in the loading magnitude on the contralateral TM joint is most evident after m. masseter and m. temporalis resection. The results from all simulations support our hypothesis that the greater the extent of muscle resection the greater the magnitude of contralateral TM joint overloading.
Subject(s)
Masticatory Muscles/physiology , Temporomandibular Joint/physiology , Biomechanical Phenomena , Humans , Mastication/physiology , MovementABSTRACT
In this paper we present a three-dimensional (3D) morphometrical assessment of human tibia sexual dimorphism based on whole bone digital representation. To detect shape-size and shape differences between sexes, we used geometric morphometric tools and colour-coded surface deviation maps. The surface-based methodology enabled analysis of sexually dimorphic features throughout the shaft and articular ends of the tibia. The overall study dataset consisted of 183 3D models of adult tibiae from three Czech population subsets, dating to the early medieval (9-10th century) (N = 65), early 20th century (N = 61) and 21st-century (N = 57). The time gap between the chronologically most distant and contemporary datasets was more than 1200 years. The results showed that, in all three datasets, sexual dimorphism was pronounced. There were some sex-dimorphic characteristics common to all three samples, such as tuberosity protrusion, anteriorly bowed shaft and relatively larger articular ends in males. Diachronic comparisons also revealed substantial shape variation related to the most dimorphic area. Male/female distinctions showed a consistent temporal trend regarding the location of dimorphic areas (shifting distally with time), while the maximal deviation between male and female digitized surfaces fluctuated and reached the lowest level in the 21st-century sample. Sex determination on a whole-surface basis yielded the lowest return of correct sex assignment in the 20th-century group, which represented the lowest socioeconomic status. The temporal variation could be attributed to changes in living conditions, the decreasing lower limb loading/labour division in the last 12 centuries having the greatest effect. Overall, the results showed that a surface-based approach is successful for analysing complex long bone geometry.
Subject(s)
Anthropometry/methods , Imaging, Three-Dimensional/methods , Sex Characteristics , Sex Determination by Skeleton/methods , Tibia/anatomy & histology , Adult , Anthropometry/instrumentation , Female , History, 20th Century , History, 21st Century , History, Medieval , Humans , Image Processing, Computer-Assisted/statistics & numerical data , Imaging, Three-Dimensional/instrumentation , Male , Principal Component Analysis/methods , Sex Determination by Skeleton/instrumentation , Tibia/physiologyABSTRACT
PURPOSE: Proximal femoral fractures are among the most commonly sustained fractures. The current treatment of stable proximal femoral fractures located in trochanteric region primarily involves the use of two systems: extramedullary dynamic hip screws and intramedullary hip nails. Given that these fractures are mainly found in the elderly population, the necessity of a repeat, due to failure of the first, may jeopardize the patient's life. Decisive factors contributing to the healing of a fracture (or the failure thereof) include fracture pattern, technical implementation of the operation (i.e., position of the implant), implant's properties and its changes in relation to the surrounding bone tissue during loading. Each screw insertion variant results in damage to various load-bearing bone structures, which can be expected to influence healing quality and stability of newly formed bone. METHOD: With the aid of a numerical model and finite element methods, the authors analyzed several different positions of IMHN/PFH-nails in the proximal femur, with the objective of determining positions with an increased risk of failure. RESULTS AND CONCLUSION: In model situations, it has been shown that in stable fractures results do not depend on absolutely precise positioning and small deflections in the nails and neck screws positions do not significantly increase the risk of failure for the entire fixation. Damage to load-bearing structures relative to various implant placements does not impact the resultant overall fixation stability. Therefore, it is not necessary to re-introduce implants in the ideal position, which can lead to reduced patient radiation doses during surgery.
Subject(s)
Bone Nails , Femur/surgery , Fracture Fixation, Intramedullary/methods , Hip Fractures/surgery , Aged , Biomechanical Phenomena , Femur/injuries , Finite Element Analysis , Fracture Fixation, Intramedullary/instrumentation , Humans , Models, Theoretical , Risk Factors , Treatment Failure , Weight-BearingABSTRACT
The aims of this study were to enable geometric morphometric sex classification using tibial proximal and distal sexual dimorphism and to evaluate the secular trend of tibial shape/form from the early 20th century to the present day. The study samples consisted of 61 adult tibias from an early 20th-century Czech population and 57 three-dimensional tibias from a 21st-century population. Discriminant function analysis with cross-validation was carried out to assess the accuracy of sex classification. Shape analysis revealed significant sex differences in both tibial extremities of the 21st-century sample and in the proximal tibia of the 20th-century population. Sex-based divergence varied between the analyzed samples, raising the issues of population specificity and diachronic change. Classification using tibial form was more successful than using tibial shape. The highest values of correct assignment (91.80% and 88.52%) were found using the form from the early 20th Czech population.
Subject(s)
Sex Determination by Skeleton/methods , Tibia/anatomy & histology , Tibia/diagnostic imaging , Adult , Aged , Discriminant Analysis , Female , Forensic Anthropology , History, 20th Century , History, 21st Century , Humans , Imaging, Three-Dimensional , Male , Middle Aged , Principal Component Analysis , Tomography, X-Ray Computed , Young AdultABSTRACT
Osteoarthritis (OA) can be used as a common name for a group of overlapping pathological conditions when the balance between the processes of degradation and synthesis, in individual parts of the cartilage, is disturbed and leads to gradual cartilage destruction. A preventive approach toward OA helps with a timely diagnosis and subsequent treatment of this disease. One of the significant risk factors affecting development of hip joint OA is the mechanism and magnitude of mechanical loading on the joint. The main motivation for this work was to verify the hypothesis involving a pathologic cycle (overloading - change of locomotion - overloading) as contributory to the development of OA and whether it can be stopped, or at least partly decelerated, by a suitable change of movement stereotypes. Providing that there is a natural balance of muscular action, from the beginning of OA, the development of OA can be significantly decelerated. The return to a natural force balance can be achieved using suitable exercise and strengthening of muscular structures. In order to verify the hypothesis, we undertook experimental measurements of gait kinematics and a computational analysis of the hip joint using the Finite Element Method.
Subject(s)
Hip Joint/physiopathology , Osteoarthritis, Hip/physiopathology , Biomechanical Phenomena , Cartilage, Articular/physiopathology , Computer Graphics , Female , Finite Element Analysis , Gait/physiology , Humans , Male , Osteoarthritis, Hip/rehabilitation , Physical Therapy Modalities , Postural Balance/physiology , Range of Motion, Articular/physiology , Risk Assessment , Software , Walking/physiology , Weight-Bearing/physiologyABSTRACT
Finite element (FE) analysis has been widely used to study the behaviour of bone or implants in many clinical applications. One of the main factors in analyses is the realistic behaviour of the bone model, because the behaviour of the bone is strongly dependent on a realistic bone material property assignment. The objective of this study was to compare isotropic and orthotropic inhomogeneous material models used for FE analyses of the "global" proximal femur and "small" specimens of the bone (cancellous and cortical). Our hypothesis was that realistic material property assignment (orthotropy) is very important for the FE analyses of small bone specimens, whereas in global FE analyses of the proximal femur, this assignment can be omitted, if the inhomogeneous material model was used. The three-dimensional geometry of the "global" proximal femur was reconstructed using CT scans of a cadaveric femur. This model was implemented into an FE simulation tool and various bone material properties, dependant on bone density, were assigned to each element in the models. The "small" specimens of cortical and cancellous bone were created in the same way as the model of the proximal femur. The results obtained from FE analyses support our above described hypothesis.
Subject(s)
Biomechanical Phenomena/methods , Bone Density/physiology , Femur/anatomy & histology , Algorithms , Cadaver , Computer Simulation , Elasticity , Femur/pathology , Finite Element Analysis , Humans , Models, Biological , Models, Statistical , Stress, Mechanical , Tomography, X-Ray Computed/methods , Weight-Bearing/physiologyABSTRACT
The aim of the study was to analyze the structure and course of osteons in the compact bone of individual regions of the upper end of the femur and to consider the possible association with the course of typical peritrochanteric fracture lines. The issue of the architecture of this region has been dealt with by a number of authors since the first half of the nineteenth century, but until the present structural analysis it has been examined only by a few authors. We analyzed the structure of bones on specimens prepared by the method of repeated grinding, impregnating and polishing of the bone surface. We grounded and subsequently evaluated the bone in 20 dry specimens of the proximal femur, where the courses of the central vascular canals were described in the region of the femoral neck, the lesser trochanter, the greater trochanter, the intertrochanteric crest and line. The osteons were incorporated into a biomechanical model of the proximal femur and compared with the FEM model and correlation with the distribution of surface stresses was described. Certain areas were identified in the region of the trochanters where the course of osteons coincided with the course of the typical fracture lines of peritrochanteric fractures with typical fragments.
Subject(s)
Femur Neck/anatomy & histology , Haversian System/anatomy & histology , Biomechanical Phenomena , Cadaver , Femoral Neck Fractures/pathology , Finite Element Analysis , Humans , Staining and Labeling , Surface PropertiesABSTRACT
Modification of ultrahigh-molecular-weight polyethylene (UHMWPE) consisting of a combination of gamma irradiation and subsequent thermal treatment has been performed in order to investigate the resultant changes to its supramolecular structure. In the first step the polymer was irradiated by gamma rays at laboratory temperature under nitrogen. Five radiation doses (25, 50, 100, 150, and 200 kGy) were applied at two dose rates (0.25 and 2.5 kGy/h). In the second step the irradiated samples were thermally treated above the UHMWPE melting temperature. Insoluble fraction, crystallinity (fraction), and lamellar periodicity were determined as functions of dose and dose rate for irradiated samples before and after thermal treatment. Both modification steps were shown to produce substantial changes in the UHMWPE structure.
Subject(s)
Joint Prosthesis , Polyethylenes/chemistry , Biocompatible Materials/chemistry , Calorimetry, Differential Scanning , Gamma Rays , Hot Temperature , X-Ray DiffractionABSTRACT
A new polymorph of pergolide mesylate or 8beta-[(methylsulfanyl)methyl]-6-propylergoline methanesulfonate, C(19)H(27)N(2)S(+).CH(3)SO(3)(-), is reported. Pergolide mesylate form II crystallizes in the trigonal system, which is unique for ergot derivatives. Although the hydrogen-bond system in form II differs completely from that in form I, the conformation of the pergolide moiety in various related structures is very similar.