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1.
J Orthop Surg Res ; 17(1): 370, 2022 Jul 30.
Article in English | MEDLINE | ID: mdl-35907886

ABSTRACT

BACKGROUND: Femoroacetabular impingement (FAI) syndrome is an established pre-osteoarthritic condition. Diagnosis is based on both clinical and radiographic parameters. An abnormal manually calculated alpha angle in magnetic resonance imaging (MRI) is traditionally utilized to diagnose abnormal femoral head-neck offset. This pilot study aimed to assess the feasibility of automated alpha angle measurements in patients with FAI syndrome, and to compare automated with manual measurements data with regard to the time and effort needed in each method. METHODS: Alpha angles were measured with manual and automated techniques, using postprocessing software in nineteen hip MRIs of FAI syndrome patients. Two observers conducted manual measurements. Intra- and inter-observer reproducibility and correlation of manual and automated alpha angle measurements were calculated using intra-class correlation (ICC) analysis. Both techniques were compared regarding the time taken (in minutes) and effort required, measured as the amount of mouse button presses performed. RESULTS: The first observer's intra-observer reproducibility was good (ICC 0.77; p < 0.001) while the second observer's was good-to-excellent (ICC 0.93; p < 0.001). Inter-observer reproducibility between both observers in the first (ICC 0.45; p < 0.001) and second (ICC 0.56; p < 0.001) manual alpha angle assessment was moderate. The intra-class correlation coefficients between manual and automated alpha angle measurements were ICC = 0.24 (p = 0.052; observer 1, 1st measurement), ICC = 0.32 (p = 0.015; observer 1, 2nd measurement), ICC = 0.50 (p < 0.001; observer 2, 1st measurement), and ICC = 0.45 (p < 0.001; observer 2, 2nd measurement). Average runtime for automatic processing of the image data for the automated assessment was 16.6 ± 1.9 min. Automatic alpha angle measurements took longer (time difference: 14.6 ± 3.9 min; p < 0.001) but required less effort (difference in button presses: 231 ± 23; p < 0.001). While the automatic processing is running, the user can perform other tasks. CONCLUSIONS: This pilot study demonstrates that objective and reliable automated alpha angle measurement of MRIs in FAI syndrome hips is feasible. Trial registration The Ethics Committee of the University of Düsseldorf approved our study (Registry-ID: 2017084398).


Subject(s)
Femoracetabular Impingement , Animals , Femoracetabular Impingement/diagnostic imaging , Femoracetabular Impingement/pathology , Hip , Hip Joint/diagnostic imaging , Hip Joint/pathology , Magnetic Resonance Imaging/methods , Mice , Pilot Projects , Reproducibility of Results
3.
Clin Orthop Relat Res ; 477(5): 1007-1018, 2019 05.
Article in English | MEDLINE | ID: mdl-30516651

ABSTRACT

BACKGROUND: Rowing exposes the femoral head and acetabulum to high levels of repetitive abutment motion and axial loading that may put elite athletes at an increased risk for developing early hip osteoarthritis. QUESTIONS/PURPOSES: Do elite rowers demonstrate characteristic hip cartilage lesions on T2 MRI sequences compared with asymptomatic individuals who do not row? METHODS: This study included 20 asymptomatic rowers (mean age, 23 ± 3 years; nine females, 11 males) who had a minimum of 5 years of intensive (≥ 12 hours/week) training. The recruiting of the rowers took place from the central German federal rowing base, which has inherent intense training and selection requirements to declare these athletes as "elite rowers." We investigated one hip per study participant. MRI was performed on a 3-T scanner. The protocol included standard sequences, a double-echo steady-state sequence, and a multiecho data image combination sequence with inline T2 calculation (= the decay of transverse magnetization arising from molecular interactions [T2] and inhomogeneities in the magnetic field resulting from tissue susceptibility-induced field distortions and variations in the magnet itself), which detects changes in water content and the disruption of collagen structure. Although extrinsic and intrinsic influences on the T2 values including diurnal effects, MR technic-derived variations, and anatomic-related regional disparities need to be taken into account, low T2 values well below 20 ms indicate cartilage degeneration. Cartilage was morphologically analyzed in the anterior, anterosuperior, superoanterior, superior, superoposterior, posterosuperior, and posterior regions of the hip and graded as follows: Grade 0 = normal; Grade 1 = signal changes; Grade 2 = cartilage abrasion; Grade 3 = cartilage loss. Labrum was classified as follows: Grade 0 = normal; Grade 1 = partial tear; Grade 2 = full-thickness tear; Grade 3 = labrum degeneration. The T2 measurement was done through a region of interest analysis. For reliability assessment, morphologic evaluation and T2 measurement were performed by two observers while one observer repeated his analysis with a time interval > 2 weeks. Intra- and interobserver reliability was determined using κ analysis and intraclass correlation coefficients. Control T2 data were derived from a previous study on 15 hips in 15 asymptomatic volunteers of similar ages (seven males and eight females) who were not competitive rowers with similar MR hardware and imaging sequences. RESULTS: Compared with the control group of asymptomatic volunteers who were not competitive rowers, we noted a high level of labrum and cartilage degeneration in the cohort of elite rowers. In the group of elite rowers, cartilage degeneration was noted in all hips. Regarding the acetabular cartilage, 271 zones could be evaluated. Of those, 44% (120 of 271) were graded normal, 6% (15 of 271) revealed signal alteration, 45% (122 of 271) demonstrated cartilage abrasion, and 5% (14 of 271) were noted to have full-thickness cartilage loss. Morphologic cartilage degeneration in the femoral head was less frequent. T2 values were lower than the control hips in all zones except for the posterior central acetabular zone (global T2 acetabular: 20 ± 6 ms, range, 9-36 ms, 95% confidence interval [CI], 19-21 ms versus 25 ± 5 ms, range, 14-44 ms, 95% CI, 24-25 ms, p < 0.001; global T2 femoral: 23 ± 7 ms, range, 9-38 ms, 95% CI, 22-24 ms versus 27 ± 5 ms, range, 17-45 ms, 95% CI, 26-28 ms, p < 0.001). The difference in T2 between the two study groups was superior in the peripheral zone of the anterosuperior region (16 ± 3 ms; range, 10-22 ms, 95% CI, 15-18 ms versus 26 ms ± 5 ms, range, 18-38 ms, 95% CI, 24-29 ms, p < 0.001). CONCLUSIONS: We found signs of hip cartilage degeneration to a much greater degree in elite rowers than in asymptomatic controls. Although causation cannot be inferred, this is concerning, and future investigations including controlled longitudinal studies both on elite and nonelite athletes with sufficient cohort size are warranted to clarify our findings. LEVEL OF EVIDENCE: Level III, therapeutic study.


Subject(s)
Athletic Performance , Cartilage, Articular/diagnostic imaging , Hip Joint/diagnostic imaging , Water Sports , Adult , Athletes , Cartilage, Articular/pathology , Female , Hip Joint/pathology , Humans , Magnetic Resonance Imaging , Male , Young Adult
4.
Cartilage ; 9(1): 30-37, 2018 01.
Article in English | MEDLINE | ID: mdl-28466651

ABSTRACT

Objective To assess age-dependent and regional differences in T2* relaxation measurements in hip joint cartilage of asymptomatic volunteers at 3 T. Design Three age cohorts (cohort 1: age 20-30 years, 15 individuals; cohort 2: age 30-40 years, 17 individuals; cohort 3: age 40-50 years, 15 individuals) were enrolled. T2* values were obtained in the central and peripheral cartilage of the acetabulum and the femoral head in 7 regions (anterior to superior and posterior). Results T2* did not differ among age cohorts in acetabular cartilage (cohort 1: 24.65 ± 6.56 ms, cohort 2: 24.70 ± 4.83 ms, cohort 3: 25.81 ± 5.10 ms, P = 0.10) and femoral head cartilage (cohort 1: 27.08 ± 8.24 ms, cohort 2: 25.90 ± 7.82 ms, cohort 3: 26.50 ± 5.61 ms, P = 0.34). Analysis of the regional T2* distribution pattern indicates increased T2* values in the anterior, anterior-superior, superior-anterior, and the posterior-superior aspects of acetabular and femoral head cartilage. For acetabular cartilage, higher values were observed in the central region (25.90 ± 4.80 ms vs. 24.21 ± 4.05 ms, P < 0.0001) whereas femoral head cartilage did not reveal such differences (26.62 ± 5.74 ms vs. 26.37 ± 5.89 ms, P = 0.44). Conclusions The T2* analysis of presumably healthy hip joint cartilage does not seem to be stratified according to age in this population. Regional T2* variation throughout hip joint cartilage is apparent in this modality.


Subject(s)
Acetabulum/diagnostic imaging , Cartilage, Articular/anatomy & histology , Femur Head/diagnostic imaging , Hip Joint/diagnostic imaging , Magnetic Resonance Imaging/methods , Acetabulum/pathology , Adult , Age Distribution , Cartilage, Articular/pathology , Female , Hip Joint/pathology , Humans , Magnetic Resonance Imaging/trends , Male , Middle Aged , Volunteers , Young Adult
5.
J Orthop Res ; 36(5): 1526-1535, 2018 05.
Article in English | MEDLINE | ID: mdl-29087625

ABSTRACT

Legg-Calvé-Perthes disease (LCPD) and slipped capital femoral epiphysis (SCFE) are two common pediatric hip disorders that affect the 3-dimensional shape and function of the proximal femur. This study applied the principles of continuum mechanics to statistical shape modeling (SSM) and determined 3-D metrics for the evaluation of shape deformations in normal growth, LCPD, and SCFE. CT scans were obtained from 32 patients with asymptomatic, LCPD, and SCFE hips ((0.5-0.9 mm)2 in-plane resolution, 0.63 mm slice thickness). SSM was performed on segmented proximal femoral surfaces, and shape deformations were described by surface displacement, strain, and growth plate angle metrics. Asymptomatic normal femurs underwent coordinated, growth-associated surface displacements and anisotropic strains that were site-specific and highest at the greater trochanter. After size- and age-based shape adjustment, LCPD femurs exhibited large displacements and surface strains in the femoral head and neck, with associated changes in femoral head growth plate angles. Mild SCFE femurs had contracted femoral neck surfaces, and surface displacements in all regions tended to increase with severity of slip. The results of this paper provide new 3-D metrics for characterizing the shape and biomechanics of the proximal femur. Statement of Clinical Significance: Quantitative 3-D metrics of shape may be useful for understanding and monitoring disease progression, identifying target regions for shape modulation therapies, and objectively evaluating the success of such therapies. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1526-1535, 2018.


Subject(s)
Femur/pathology , Legg-Calve-Perthes Disease/pathology , Slipped Capital Femoral Epiphyses/pathology , Adolescent , Biomechanical Phenomena , Child , Femur/growth & development , Femur/physiopathology , Growth Plate/pathology , Humans
6.
Cartilage ; 8(4): 400-405, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28466650

ABSTRACT

Objective To identify if the time of day and pre-imaging exercise matter while performing T2* mapping of hip joint cartilage at 3 T. Design Nine asymptomatic healthy volunteers (mean age 27.4 ± 4.0 years) with no obvious morphological evidence of cartilage damage were enrolled. The MRI protocol included a double-echo steady state (DESS) sequence for morphological cartilage assessment and a multi-echo data image combination sequence for the T2* measurement. T2* values were obtained between 8 and 11 a.m., between 3 and 6 p.m., and after 50 knee-bends at several time points of each measurement (0, 15, 30, 45, 60 minutes). Results We observed no differences ( P = 0.47) between the T2* values obtained in the morning (T2* = 22.9 ± 3.0 ms) and those measured in the afternoon (T2* = 23.2 ± 3.2 ms). We also observed no statistically significant differences between the T2* values at different time points ( P = 0.67) or after 50 knee-bends ( P = 0.43). Conclusions Timing of the scan and pre-imaging exercise clearly did not matter in this modality. This study consolidates the value of T2* imaging in hip joint cartilage that seems to be independent of diurnal effects and physical activity prior to MRI.

7.
Eur Radiol ; 27(10): 4360-4371, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28432505

ABSTRACT

OBJECTIVES: To assess the diagnostic accuracy of a high-resolution, three-dimensional (3D) double-echo steady-state (DESS) sequence with radial imaging at 3 Tesla (T) for evaluating cartilage and labral alterations in the hip. METHODS: Magnetic resonance imaging (MRI) data obtained at 3 T, including radially reformatted DESS images and intraoperative data of 45 patients (mean age 42 ± 13.7 years) who underwent hip arthroscopy, were compared. The acetabular cartilage and labrum of the upper hemisphere of the acetabulum and the central femoral head cartilage were evaluated. Sensitivity, specificity, accuracy, and negative and positive predictive values were determined. RESULTS: Sensitivity, specificity and accuracy of the DESS technique were 96.7%, 75% and 93.7% for detecting cartilage lesions and 98%, 76.2% and 95.9% for detecting labral lesions. The positive and negative predictive values for detecting or ruling out cartilage lesions were 96% and 78.9%. For labral lesions, the positive and negative predictive values were 97.5% and 80%. CONCLUSION: A high-resolution, 3D DESS technique with radial imaging at 3 T demonstrated high accuracy for detecting hip cartilage and labral lesions with excellent interobserver agreement and moderate correlation between MRI and intraoperative assessment. KEY POINTS: • High-resolution, 3D DESS with radial imaging allows accurate cartilage and labrum evaluation. • DESS demonstrated high sensitivity, specificity, accuracy for detecting cartilage and labral lesions. • Highly accurate sequence may influence treatment decisions in patients with hip pain.


Subject(s)
Cartilage, Articular/diagnostic imaging , Hip Joint/diagnostic imaging , Magnetic Resonance Imaging/methods , Acetabulum/diagnostic imaging , Acetabulum/pathology , Adolescent , Adult , Aged , Arthroscopy , Cartilage, Articular/pathology , Female , Femur Head/diagnostic imaging , Femur Head/pathology , Hip Joint/pathology , Humans , Imaging, Three-Dimensional , Male , Middle Aged , Sensitivity and Specificity , Young Adult
8.
J Am Acad Orthop Surg Glob Res Rev ; 1(7): e038, 2017 Oct.
Article in English | MEDLINE | ID: mdl-30211362

ABSTRACT

INTRODUCTION: Nerve injuries can occur from major hip surgeries, and some may be significant. Our goal was to assess the feasibility and safety of neuromonitoring during hip preservation surgery and the incidence of alerting events during such monitoring. METHODS: Twenty-five adult patients underwent surgical hip dislocation for femoroacetabular impingement. Upper and lower extremity somatosensory evoked potentials, lower extremity transcranial motor evoked potentials, and lower extremity electromyography were recorded. RESULTS: We observed a temporary reduction of the monitored parameters in twelve patients (48%) during surgery. There were no clinically significant neurological deficits postoperatively in any cases. DISCUSSION: Neuromonitoring did demonstrate events during hip surgery in our case series. Although it may not be practical to use neuromonitoring in all major hip surgeries, it may be prudent from the perspective of patient safety to use it in high-risk cases, including those requiring prolonged surgical time; in patients with high body mass index, excessive deformity correction, and preexisting neuropathy; and in revision cases, among others.

9.
J Orthop Res ; 34(4): 717-24, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26466861

ABSTRACT

To obtain T2* values in histologically evaluated healthy ovine intervertebral discs of the cervical and lumbar spine. Intervertebral discs of nine sheep and nine lambs underwent histological assessment with the modified Boos score for grading of disc degeneration. Discs with a score <10 points (maximum = 40 points) underwent T2* mapping (n = 64). Mid-sagittal T2* values were obtained in five regions: Anterior annulus fibrosus, anterior nucleus pulposus, central nucleus pulposus, posterior nucleus pulposus, and posterior annulus fibrosus. We noted a zonal T2* distribution with high values in the central nucleus and low T2* values in the anterior and posterior annulus fibrosus. The T2* values were higher in lamb than in sheep IVDs for both cervical and lumbar spine (p < 0.001). The T2* values were also higher in the cervical than in the lumbar spine (p = 0.029 for sheep and p < 0.001 for lamb IVDs). The T2* values obtained in these ovine intervertebral discs can serve as baseline values for future T2* measurements both in health and disease.


Subject(s)
Cervical Vertebrae/anatomy & histology , Intervertebral Disc/anatomy & histology , Lumbar Vertebrae/anatomy & histology , Sheep/anatomy & histology , Animals , Magnetic Resonance Imaging , Reference Values
10.
Front Surg ; 2: 34, 2015.
Article in English | MEDLINE | ID: mdl-26258129

ABSTRACT

Symptomatic femoroacetabular impingement (FAI) is now a known precursor of early osteoarthritis (OA) of the hip. In terms of clinical intervention, the decision between joint preservation and joint replacement hinges on the severity of articular cartilage degeneration. The exact threshold during the course of disease progression when the cartilage damage is irreparable remains elusive. The intention behind radiographic imaging is to accurately identify the morphology of osseous structural abnormalities and to accurately characterize the chondrolabral damage as much as possible. However, both plain radiographs and computed tomography (CT) are insensitive for articular cartilage anatomy and pathology. Advanced magnetic resonance imaging (MRI) techniques include magnetic resonance arthrography and biochemically sensitive techniques of delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), T1rho (T1ρ), T2/T2* mapping, and several others. The diagnostic performance of these techniques to evaluate cartilage degeneration could improve the ability to predict an individual patient-specific outcome with non-surgical and surgical care. This review discusses the facts and current applications of biochemical MRI for hip joint cartilage assessment covering the roles of dGEMRIC, T2/T2*, and T1ρ mapping. The basics of each technique and their specific role in FAI assessment are outlined. Current limitations and potential pitfalls as well as future directions of biochemical imaging are also outlined.

11.
BMJ Open ; 5(2): e006895, 2015 Feb 09.
Article in English | MEDLINE | ID: mdl-25667150

ABSTRACT

OBJECTIVES: Accurate assessment of cartilage status is increasingly becoming important to clinicians for offering joint preservation surgeries versus joint replacements. The goal of this study was to evaluate the validity of three-dimensional (3D), gradient-echo (GRE)-based T2* and T1Gd mapping for the assessment of various histological severities of degeneration in knee joint cartilage with potential implications for clinical management. METHODS: MRI and histological assessment were conducted in 36 ex vivo lateral femoral condyle specimens. The MRI protocol included a 3D GRE multiecho data image combination sequence in order to assess the T2* decay, a 3D double-echo steady-state sequence for assessment of cartilage morphology, and a dual flip angle 3D GRE sequence with volumetric interpolated breathhold examination for the T1Gd assessment. The histological sample analysis was performed according to the Mankin system. The data were then analysed statistically and correlated. RESULTS: We observed a significant decrease in the T2* and T1Gd values with increasing grades of cartilage degeneration (p<0.001) and a moderate correlation between T2* (r=0.514)/T1Gd (r=0.556) and the histological grading of cartilage degeneration (p<0.001). In addition, we noted a zonal variation in the T2* and T1Gd values reflecting characteristic zonal differences in the biochemical composition of hyaline cartilage. CONCLUSIONS: This study outlines the potential of GRE-based T2* and T1Gd mapping to identify various grades of cartilage damage. Early changes in specific zones may assist clinicians in identifying methods of early intervention involving the targeted joint preservation approach versus moving forward with unicompartmental, bicompartmental or tricompartmental joint replacement procedures. TRIAL REGISTRATION NUMBER: DRKS00000729.


Subject(s)
Cartilage Diseases/pathology , Cartilage, Articular/pathology , Femur/pathology , Knee Joint/pathology , Knee/pathology , Magnetic Resonance Imaging/methods , Severity of Illness Index , Adult , Aged , Aged, 80 and over , Humans , In Vitro Techniques , Male , Middle Aged , Reproducibility of Results
12.
Hip Int ; 25(2): 104-14, 2015.
Article in English | MEDLINE | ID: mdl-25362879

ABSTRACT

Slipped capital femoral epiphysis (SCFE) is a common hip condition that can be disabling. In this review, we provide an orientation on current trends in the clinical management of SCFE including conventional procedures and specialised surgical developments. Different methods of fixation of the epiphysis, risks of complications, and the rationale of addressing deformity, primarily or secondarily, are presented. Although improved understanding of the anatomy, vascularity and implications of residual deformity have changed management strategies, the best modality of treatment that would restore complete vascularity to the femoral head and prevent any residual deformity, impingement and early osteoarthritis remains elusive.


Subject(s)
Femoracetabular Impingement/surgery , Orthopedic Procedures/methods , Range of Motion, Articular/physiology , Slipped Capital Femoral Epiphyses/diagnostic imaging , Slipped Capital Femoral Epiphyses/surgery , Bone Nails , Bone Wires , Female , Femoracetabular Impingement/diagnostic imaging , Femur Head/diagnostic imaging , Femur Head/pathology , Follow-Up Studies , Humans , Male , Orthopedic Procedures/instrumentation , Osteoarthritis, Hip/prevention & control , Pain Measurement , Radiography , Risk Assessment , Severity of Illness Index , Treatment Outcome
13.
Eur J Radiol ; 84(2): 284-9, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25523822

ABSTRACT

OBJECTIVE: To study the effect of repetitive joint loading on the T2(*) assessment of knee joint cartilage. MATERIALS AND METHODS: T2(*) mapping was performed in 10 non-professional marathon runners (mean age: 28.7±3.97 years) with no morphologically evident cartilage damage within 48h prior to and following the marathon and after a period of approximately four weeks. Bulk and zonal T2(*) values at the medial and lateral tibiofemoral compartment and the patellofemoral compartment were assessed by means of region of interest analysis. Pre- and post-marathon values were compared. RESULTS: There was a small increase in the T2(*) after running the marathon (30.47±5.16ms versus 29.84±4.97ms, P<0.05) while the T2(*) values before the marathon and those after the period of convalescence were similar (29.84±4.97ms versus 29.81±5.17ms, P=0.855). Regional analyses revealed lower T2(*) values in the medial tibial plateau (P<0.001). CONCLUSIONS: It appears that repetitive joint loading has a transient influence on the T2(*) values. However, this effect is small and probably not clinically relevant. The low T2(*) values in the medial tibial plateau may be related to functional demand or early cartilage degeneration.


Subject(s)
Cartilage, Articular/pathology , Knee Joint/pathology , Magnetic Resonance Imaging , Weight-Bearing , Adult , Biomechanical Phenomena , Cartilage, Articular/anatomy & histology , Female , Humans , Knee Joint/anatomy & histology , Knee Joint/physiopathology , Male , Running
14.
Skeletal Radiol ; 43(10): 1429-45, 2014 Oct.
Article in English | MEDLINE | ID: mdl-24643762

ABSTRACT

With advances in joint preservation surgery that are intended to alter the course of osteoarthritis by early intervention, accurate and reliable assessment of the cartilage status is critical. Biochemically sensitive MRI techniques can add robust biomarkers for disease onset and progression, and therefore, could be meaningful assessment tools for the diagnosis and follow-up of cartilage abnormalities. T2* mapping could be a good alternative because it would combine the benefits of biochemical cartilage evaluation with remarkable features including short imaging time and the ability of high-resolution three-dimensional cartilage evaluation-without the need for contrast media administration or special hardware. Several in vitro and in vivo studies, which have elaborated on the potential of cartilage T2* assessment in various cartilage disease patterns and grades of degeneration, have been reported. However, much remains to be understood and certain unresolved questions have become apparent with these studies that are crucial to the further application of this technique. This review summarizes the principles of the technique and current applications of T2* mapping for articular cartilage assessment. Limitations of recent studies are discussed and the potential implications for patient care are presented.


Subject(s)
Cartilage Diseases/pathology , Cartilage, Articular/pathology , Magnetic Resonance Imaging/methods , Osteoarthritis/pathology , Humans , Image Interpretation, Computer-Assisted/methods , Imaging, Three-Dimensional/methods , Magnetic Resonance Imaging/trends
15.
Skeletal Radiol ; 43(4): 443-52, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24425347

ABSTRACT

OBJECTIVE: To establish baseline T2* values in healthy knee joint cartilage at 3 T. MATERIALS AND METHODS: Thirty-four volunteers (mean age: 24.6 ± 2.7 years) with no history or clinical findings indicative of any knee joint disease were enrolled. The protocol included a double-echo steady-state (DESS) sequence for morphological cartilage evaluation and a gradient-echo multi-echo sequence for T2* assessment. Bulk and zonal T2* values were assessed in eight regions: posterior lateral femoral condyle; central lateral femoral condyle; trochlea; patella; lateral tibial plateau; posterior medial femoral condyle; central medial femoral condyle; and medial tibial plateau. Statistical evaluation comprised a two-tailed t test and a one-way analysis of variance to identify zonal and regional differences. RESULTS: T2* mapping revealed higher T2* values in the superficial zone in all regions (P values ≤ 0.001) except for the posterior medial femur condyle (P = 0.087), and substantial regional differences demonstrating superior values in trochlear cartilage, intermediate values in patellar and central femoral condylar cartilage, and low T2* values in posterior femoral condylar cartilage and tibial plateau cartilage. CONCLUSION: Substantial regional differences in T2* measures should be taken into consideration when conducting T2* mapping of knee joint cartilage.


Subject(s)
Cartilage, Articular/anatomy & histology , Cartilage, Articular/physiology , Image Interpretation, Computer-Assisted/methods , Knee Joint/anatomy & histology , Knee Joint/physiology , Magnetic Resonance Imaging/methods , Adult , Female , Germany , Humans , Image Interpretation, Computer-Assisted/standards , Magnetic Resonance Imaging/standards , Male , Reference Values , Reproducibility of Results , Sensitivity and Specificity , Young Adult
17.
Orthop Rev (Pavia) ; 5(3): e29, 2013 Oct 02.
Article in English | MEDLINE | ID: mdl-24191189

ABSTRACT

The literature available on patient-orientated outcomes of operative management for clavicle fractures in adolescents is fairly limited. Open surgical treatment of displaced midshaft fractures of the clavicle continues to be a topic of controversy. Traditional treatment of clavicle fractures has been via non-operative methods in both children and adults. Management in adolescent patients remains controversial, and rightly so, as the traditional experience from non-operative methods has been regarded as satisfactory, while the literature on the more recent approach towards fixing some of these fractures is evolving. We present a review of relevant literature.

18.
Hip Int ; 23 Suppl 9: S61-70, 2013.
Article in English | MEDLINE | ID: mdl-23873509

ABSTRACT

The analysis and treatment of hips with healed Legg-Calvé-Perthes disease (LCPD) differs substantially from the treatment in the acute phase of the disease. More specifically, the treating orthopaedic surgeon is often faced with a complex three-dimensional pathomorphology of the hip that is difficult to understand and correct. To date, none of the current classification systems provide a useful decision-making algorithm with regards to the type of surgical intervention necessary to improve hip function in patients with sequelae of LCPD. The conceptual recognition of the femoroacetabular impingement (FAI) and the ability to safely dislocate the hip have revolutionised our diagnostic and therapeutic algorithm for joint-preserving surgery of hips with structural residuals of LCPD. We present a systematic approach to analyse femoral and acetabular pathomorphologic features. The resulting pathomechanisms and the surgical treatment options are presented.


Subject(s)
Femoracetabular Impingement , Legg-Calve-Perthes Disease , Orthopedic Procedures/methods , Algorithms , Femoracetabular Impingement/epidemiology , Femoracetabular Impingement/etiology , Femoracetabular Impingement/surgery , Global Health , Humans , Incidence , Legg-Calve-Perthes Disease/complications , Legg-Calve-Perthes Disease/epidemiology , Legg-Calve-Perthes Disease/surgery , Range of Motion, Articular
19.
J Bone Joint Surg Am ; 95(13): e90, 2013 Jul 03.
Article in English | MEDLINE | ID: mdl-23824395

ABSTRACT

BACKGROUND: Symptomatic femoroacetabular impingement is a known prearthritic condition. Impingement morphology is poorly defined in the adolescent population. The purpose of this study was to document the prevalence of radiographic impingement morphology in adolescents with no symptomatic hip problems. METHODS: Ninety anteroposterior images of the hip in forty-five consecutive adolescents with scoliosis met the inclusion criteria. Sex distribution was equal. The second cohort (ninety hips) was an age-matched group with no scoliosis. None had symptomatic hip problems. Images were analyzed for coxa profunda, protrusio acetabuli, Tönnis angle, anteroposterior alpha angle, center-edge angle, acetabular crossover, ischial spine sign, and neck-shaft angle. RESULTS: Of the 180 hips, 92.8% demonstrated at least one parameter suggesting impingement morphology, whereas 52.2% showed at least two signs. Evidence of coxa profunda was seen in 81.7% of the hips, while a negative Tönnis angle was seen in 31.1% and a center-edge angle indicative of acetabular overcoverage was seen in 15%. An acetabular crossover sign was detected in 27.2% of the hips, while an abnormal anteroposterior alpha angle was found in 5.6% of the hips in male patients and 6.7% of the hips in female patients. Statistical analysis revealed that abnormal alpha angles (p = 0.029), crossover signs (p = 0.029), and ischial spine signs (p = 0.026) were more common in the cohort without scoliosis, and coxa profunda was more common in females (p = 0.034). CONCLUSIONS: There was a high prevalence of radiographic impingement morphology beyond the spectrum of normal in this double-cohort study of adolescents. Femoroacetabular impingement remains a dynamic problem, and we caution against relying only on the use of hard-set static radiographic parameters when evaluating femoroacetabular impingement. This study raises the important question of what morphologic characteristics should be defined as abnormal, when at least one finding of impingement morphology is noted in such a large segment of the population. On the basis of the normative data obtained, reference values for radiographic parameters of femoroacetabular impingement morphology should be redefined. Normal values for a Tönnis angle were between -8° and 14°, the upper limit of the center-edge angle was 44°, and the normal values for femoral neck-shaft angle were between 121° and 144°. Surgical indications should be tailored to physical examination findings and not radiographic findings alone.


Subject(s)
Femoracetabular Impingement/diagnostic imaging , Adolescent , Adult , Biomechanical Phenomena , Child , Cohort Studies , Female , Femoracetabular Impingement/physiopathology , Femur Neck/anatomy & histology , Hip Joint/diagnostic imaging , Humans , Male , Physical Examination , Radiography , Reference Values , Scoliosis/diagnostic imaging , Scoliosis/physiopathology , Young Adult
20.
Pediatr Radiol ; 43(12): 1599-605, 2013 Dec.
Article in English | MEDLINE | ID: mdl-23794055

ABSTRACT

BACKGROUND: With recent changing approaches to the management of slipped capital femoral epiphysis (SCFE), the accurate radiographic assessment of maximum extent of displacement is crucial for planning surgical treatment. OBJECTIVE: To determine what plane best represents the maximum SCFE displacement as quantified by the head-neck angle difference (HNAD), whether HNAD can quantitatively differentiate the SCFE cohort from the normal cohort, based on CT, and how Southwick slip angle (SSA) compares to HNAD. MATERIALS AND METHODS: We reviewed 19 children with SCFE (23 affected hips) with preoperative CT scans and 27 age- and sex-matched children undergoing abdominal CT for non-orthopedic problems. Head-neck angle (HNA), the angle between the femoral epiphysis and the neck axis, was measured in three planes on each hip and the HNAD (affected - unaffected hip) was determined. SSA was measured on radiographs. RESULTS: The coronal HNAD (mean 8.7°) was less than both the axial-oblique (mean 30.7°) and sagittal (mean 37.4°) HNADs, which were also greater than the HNADs of the normal cohort. Grouping HNAD measurements by SSA severity classification did not consistently distinguish between SCFE severity levels. CONCLUSION: Axial-oblique and sagittal planes best represent the maximum SCFE displacement while biplanar radiograph may underestimate the extent of the displacement, thereby potentially altering the management between in situ pinning and capital realignment.


Subject(s)
Anatomic Landmarks/diagnostic imaging , Femur Head/abnormalities , Femur Head/diagnostic imaging , Patient Positioning/methods , Radiographic Image Interpretation, Computer-Assisted/methods , Slipped Capital Femoral Epiphyses/diagnostic imaging , Tomography, X-Ray Computed/methods , Adolescent , Algorithms , Child , Female , Humans , Male , Radiographic Image Enhancement/methods , Reproducibility of Results , Sensitivity and Specificity
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