1.
J Org Chem
; 89(13): 9450-9461, 2024 Jul 05.
Article
in English
| MEDLINE
| ID: mdl-38867507
ABSTRACT
Visible-light-promoted thiolation of benzyl chlorides with thiosulfonates is disclosed via an electron donor-acceptor complex strategy. In addition to efficiently delivering a series of arylbenzylsulfide compounds, versatile thioglycosides were also successfully constructed by applying the metal- and photocatalyst-free protocol. Preliminary mechanistic studies suggest that a radical-radical coupling process was involved in this transformation.