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1.
Immunol Allergy Clin North Am ; 43(3): 503-512, 2023 08.
Article in English | MEDLINE | ID: mdl-37394256

ABSTRACT

Acute coronary syndrome (ACS) in the setting of an allergic/immunologic reaction is known as Kounis syndrome. It is an underdiagnosed and underrecognized disease entity. One must keep a high index of suspicions when managing a patient presenting with cardiac as well as allergic symptoms. There are 3 main variants to the syndrome. Treating the allergic reaction may alleviate the pain; however, ACS guidelines should be followed if cardiac ischemia is present.


Subject(s)
Acute Coronary Syndrome , Hypersensitivity , Kounis Syndrome , Humans , Kounis Syndrome/diagnosis , Kounis Syndrome/etiology , Kounis Syndrome/therapy , Acute Coronary Syndrome/diagnosis , Acute Coronary Syndrome/etiology , Acute Coronary Syndrome/therapy
2.
Emerg Med Clin North Am ; 40(1): 69-78, 2022 Feb.
Article in English | MEDLINE | ID: mdl-34782092

ABSTRACT

Acute coronary syndrome (ACS) in the setting of an allergic/immunologic reaction is known as Kounis syndrome. It is an underdiagnosed and underrecognized disease entity. One must keep a high index of suspicions when managing a patient presenting with cardiac as well as allergic symptoms. There are 3 main variants to the syndrome. Treating the allergic reaction may alleviate the pain; however, ACS guidelines should be followed if cardiac ischemia is present.


Subject(s)
Kounis Syndrome/complications , Kounis Syndrome/immunology , Humans , Kounis Syndrome/physiopathology
3.
West J Emerg Med ; 18(3): 474-478, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28435499

ABSTRACT

Accelerated diagnostic pathways (ADP) have been designed to identify low-risk chest pain patients in the emergency department. This review article discusses the Asia-Pacific Evaluation of Chest Pain Trial (ASPECT) score, the Accelerated Diagnostic Protocol for Chest Pain Trial (ADAPT) score, the Emergency Department Assessment of Chest Pain Score (EDACS), the HEARTScore and the HEART pathway. These ADPs have been validated in various studies and aid the emergency provider with identifying the low-risk chest pain patient who is appropriate for discharge home, while at the same time highlighting those patients who would benefit from further in-patient work up. These approaches should be paired with patient input and shared decision-making strategies.


Subject(s)
Chest Pain/diagnosis , Critical Pathways , Emergency Service, Hospital , Point-of-Care Systems/statistics & numerical data , Biomarkers/blood , Chest Pain/blood , Chest Pain/therapy , Clinical Decision-Making , Electrocardiography , Humans , Medical History Taking , Patient Discharge , Risk Assessment , Time Factors , Troponin/blood
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