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1.
Med Tr Prom Ekol ; (3): 30-4, 2012.
Article in Russian | MEDLINE | ID: mdl-22702133

ABSTRACT

In the present work influence of perlite sand has been studied on a skin of Sprague-Dawley male rat (300-350 g). The biopsy of intact rat skin has been used as control. Contact of the perlite sand with animals' skin causes the reaction of an inflammation amplifying with increase of duration of the influence of substance. Therefore, despite an inert chemical compound, long contact with perlite sand in conditions of production can promote development of skin diseases. From the result of this investigation it is concluded that perlite sand causes irritating action on the skin and it is necessary to apply additional protective means to workers contacting to this substance.


Subject(s)
Aluminum Oxide/toxicity , Dermatitis, Contact/etiology , Dermatitis, Contact/pathology , Silicon Dioxide/toxicity , Skin/drug effects , Skin/pathology , Animals , Male , Occupational Exposure/adverse effects , Rats , Rats, Sprague-Dawley
2.
Biofizika ; 53(5): 886-93, 2008.
Article in Russian | MEDLINE | ID: mdl-18954020

ABSTRACT

The effect of negatively charged ions on respiratory organs and blood of rats has been studied. It was shown that the inhaling of negative air ions (NAI) for 60 min with a concentration of NAI at the place of location of animals 320-350 000 ions/cm2 activated the secretion of goblet cells without damaging the mucosa of the trachea and changed the spectrum of proteins of bronchopulmonary lavage. It was also found that the spontaneous production of reactive oxygen species (ROS) by cells of nonfractionated blood after the exposure to NAI increased in both males and females; the intensity of ROS generation induced by opsonized zymosan increased only in females. Different sensitivity of the antioxidant enzymes superoxide dismutase and glutathione reductase of blood to NAI in females and males was revealed. These results enable one to consider the effect of NAI as priming and a weak activation of the respiratory organs through the direct action on the mucosa of the primary target organs of the respiratory tract and then on the blood.


Subject(s)
Air , Glutathione Reductase/blood , Ions/pharmacology , Respiratory Mucosa/metabolism , Superoxide Dismutase/blood , Trachea/metabolism , Animals , Bronchoalveolar Lavage Fluid , Female , Male , Rats , Rats, Wistar , Reactive Oxygen Species/metabolism , Respiratory Mucosa/cytology , Time Factors , Trachea/cytology , Zymosan/pharmacology
3.
Arkh Patol ; 56(6): 71-4, 1994.
Article in Russian | MEDLINE | ID: mdl-7605224

ABSTRACT

Coronary artery walls in 18 autopsy cases of myocardial infarction, 18 cases of acute coronary failure, 21 cases of violent death of presenile and senile subjects with age-specific atherosclerosis and 25 cases of violent death of healthy young subjects were studied histometrically. Maximal content of mast cells in the coronary artery adventitia was found in the group of young healthy persons, minimal being in the group of old healthy persons. The count of mast cells in subjects who died of myocardial infarction and acute coronary failure was higher than in those with age-specific atherosclerosis, but lower than in young healthy persons. The number of mast cells in the walls of coronary arteries correlates with the degree of their lipidosis and to a less extent with the degree of plasmorrhagia.


Subject(s)
Arteriosclerosis/pathology , Coronary Vessels/pathology , Endothelium, Vascular/pathology , Mast Cells/pathology , Myocardial Ischemia/pathology , Acute Disease , Adult , Aged , Aged, 80 and over , Case-Control Studies , Evaluation Studies as Topic , Female , Humans , Lipidoses , Male , Middle Aged
4.
Biofizika ; 39(3): 548-53, 1994.
Article in Russian | MEDLINE | ID: mdl-8043645

ABSTRACT

This paper is devoted to the problem of biofeedback and self-regulation in the human neuromuscular system. On the base of our experimental data we revealed the existence of the three informative frequency band in the range 100-150, 140-210 and 180-300 p.s. The task of measuring of the autooscillations is solved by inserting the appropriate muscle area as the positive elements of electromechanical feedback generator including the amplifier and two electromechanical transducers. The tested muscle group being strained and actively or passively relaxed in turn. The integrated relationships between the autooscillations of the muscle group of the right and left hand turned out the family of straight lines. We got a mathematical expressions for the characteristics curves with the discrete constant coefficient.


Subject(s)
Biofeedback, Psychology , Muscles/physiology , Nervous System Physiological Phenomena , Humans
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