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J Pediatr ; 218: 228-230.e1, 2020 03.
Article in English | MEDLINE | ID: mdl-31748120

ABSTRACT

We describe 10 children with Alagille syndrome and inflammatory arthritis. In our centers, the prevalence of chronic arthritis in patients with Alagille syndrome is approximately 50 times higher compared with the general population. Arthritis was refractory to most treatment. Patients with Alagille syndrome should routinely be screened for musculoskeletal symptoms.


Subject(s)
Alagille Syndrome/complications , Alagille Syndrome/diagnosis , Arthritis, Juvenile/complications , Arthritis, Juvenile/diagnosis , Adolescent , Alagille Syndrome/epidemiology , Arthritis, Juvenile/epidemiology , Child , Child, Preschool , Chronic Disease , Contrast Media , Female , Humans , Inflammation , Liver Transplantation , Magnetic Resonance Imaging , Male , Pediatrics , Retrospective Studies , Rheumatology , Surveys and Questionnaires , Wrist/diagnostic imaging
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