ABSTRACT
The clinical signs of varicocele typically emerge during the puberty. Varicocele is found in 15% of men in the general population and 25-35% and 50-80% of males presenting with primary and secondary infertility, respectively. Factors contributing to the development and recurrence of varicocele include the abnormalities of the testicular venous drainage and outflow (varicose veins are more common on the left than on the right), the anatomical features of the veins of the testicular and prostatic venous plexus, the patients constitution, predisposition to constipation or diarrhea, physical activity. At present, the genetic defects, including the undifferentiated connective tissue dysplasia (UCTD) with hereditary insufficiency of venous valves and the weakness of the testicular vein walls, are thought to play a key role in the formation of a varicocele. Considering the importance of varicocele in the development of male infertility, the role of the UCTD in varicocele formation warrants a detailed investigation to provide an individual approach to patients and predict the disease recurrence.
Subject(s)
Undifferentiated Connective Tissue Diseases/complications , Varicocele/epidemiology , Varicocele/etiology , Age Factors , Humans , Male , Recurrence , Undifferentiated Connective Tissue Diseases/genetics , Varicocele/geneticsABSTRACT
Experiments were carried out to study the possibility and conditions of postmortem hemorrhage with special reference to the victims of blunt trauma. Comparative morphological characteristics of resulting injuries are exemplified. Cases of postmortem bleeding following gunshot wounds are described. Case reports are presented illustrating the possibility of bruise migration.
Subject(s)
Forensic Pathology , Hemorrhage/pathology , Postmortem Changes , Soft Tissue Injuries/pathology , Cadaver , Diagnosis, Differential , Hemorrhage/etiology , Humans , Soft Tissue Injuries/etiologyABSTRACT
Polyfepan, a sorbent, included in the complex of therapeutic measures for the patients with exacerbations of chronic enterocolitis, has considerably reduced the terms necessary to arrest the major symptoms of the condition vs. the reference group. The effect was the most manifest when the sorbent was combined with polyenzyme drugs. Laboratory tests and rat experiments have helped validate polyfepan action as the agent binding microorganisms and their toxins on its surface and fixing the enzyme vector at the site of the pathologic process.
